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Objective To investigate the effects of all-trans retinoic acid,arsenic trioxide(As2O3) and daunorubicin on tissue factor expression in acute promyelocytic leukemia cell line NB4 cells.

目的 探讨全反式维甲酸、三氧化二砷(As2O3)及柔红霉素对急性早幼粒细胞白血病细胞株NB4细胞组织因子表达的影响。

Objective:To observe the therapeutic efficacy and side effect of all-trans retinoic acid combined with arsenic trioxide(As2O3)on newly-diagnosed patients with acute promyelocytic leukemia.

目的:观察全反式维甲酸联合三氧化二砷(As2O3)治疗初发急性早幼粒细胞白血病的疗效和不良反应。

AbstractObjectiveTo observe the therapeutic efficacy of all-trans retinoic acid combined with arsenic trioxide(As2O3) on acute promyelocytic leukemia.

中文摘要:摘要目的研究全反式维A酸联合三氧化二砷治疗急性早幼粒细胞性白血病可产生的协同作用。

Objective To study the effects of all-trans retinoic acid and arsenic tioxide on the cell growth and the expression of NF-кB and ROS in NB4 cells. Methods NB4 cells were treated with ATRA alone or in combination with As2O3 in different concentrations.

目的 探讨全反式维甲酸联合三氧化二砷(As2O3)对NB4细胞的生长以及核因子-кB、活性氧表达的影响。

Acute promyelocytic leukemia ; All-transrefinoic acid ; Arsenic

急性早幼粒细胞白血病;全反式维甲酸;砷剂

Over the past year, the group evaluated the seven-year follow-up results of therapeutic effects of all-trans retinoic acid and arsenic trioxide (As2O3) combined treatment in newly diagnosed acute promyelocytic leukemia. We also studied the mechanism of therapeutic effects of Imatinib and As4S4 combined treatment in CML cell line and animal model. These two papers were published on PNAS.

过去的一年中,本课题组总结完成了全反式维甲酸和三氧化二砷联合治疗初发急性早幼粒细胞白血病的七年临床随访资料的疗效评估;在慢性粒细胞性白血病,完成了应用As4S4和STI571联合治疗作用的细胞、分子和整体动物水平的机制研究,这两部分工作均已发表于PNAS。

Telomerase ; Ovarian neoplasms ; Azidothymidine ; Cisplatin ; All trans retinoic acid

端粒酶;卵巢癌;叠氮胸苷;顺铂;全反式维甲酸

The city's Board of Health has ordered them to get artificial trans fats out of their food by July 1 - or face heavy fines.

健康中心已经下令,在七月一日前在食物中不可参入人工反式脂肪,否则会罚重款。

Based on Britten and Davidson's gene regular model, it is very possible that human sex determining is regulated by transactivative model of multiple integrator genes plus multiple receptor sites.

根据Britten和Davidson提出的基因凋节模式,我们认为人类性别决定可能是一个多整合子/多受子的反式活化作用来调控的。

The results show that the styrene is better than trans 2 butene as working gas, and the deposition rate is about 3~4 μm/h for styrene, 1 μm/h for the trans 2 butene.

使用反式 2 丁烯为工作气体的沉积速率相对较慢,最高为 1μm/h ,而使用苯乙烯时,沉积速率提高到 3~ 4μm/h。

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And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47:5 法老对约瑟说,你父亲和你弟兄们到你这里来了。

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