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Result: General rate of side-effect of application ionic-contrast is 5.04%; Generant rate of side-effect of application non-ioni...

合理选择造影剂、严格筛选高危人群和预防性给药以及完备的抢救措施能明显降低造影剂的副反应率和致死率。

Despite the poor response rates in the chemotherapy-alone group, Dr. Burstein believes that metronomic chemotherapy combined with bevacizumab should be investigated further, given the tolerability of the agents and the preclinical rationale for efficacy. When asked why cyclophosphamide and methotrexate were selected for metronomic chemotherapy, he observed that many patients in this setting are already somewhat chemotherapy-resistant.

尽管只接受化学疗法的病患反应率很低,Burstein医师相信节律性化学疗法加上bevacizumab应该进一步研究,因为该药物的耐受性良好,而且临床前实验认为是有效的;当被问到为什么选择cyclophosphamide与methotrexate作为节律性化学疗法的药物,他观察发现,许多病患在这个时候已经对许多化学疗法产生抗药性。

Despite the poor response rates in the chemotherapy-alone group, Dr. Burstein believes that metronomic chemotherapy combined with bevacizumab should be investigated further, given the tolerability of the agents and the preclinical rationale for efficacy. When asked why cyclophosphamide and methotrexate were selected for metronomic chemotherapy, he observed that many patients in this setting are already somewhat chemotherapy-resistant.

尽管只接受化学疗法的病患反应率很低,Burstein医师相信节律性化学疗法加上bevacizumab应该进一步研究,因为该药物的耐受性良好,而且临床前实验认为是有效的;当被问到为什麼选择cyclophosphamide与methotrexate作为节律性化学疗法的药物,他观察发现,许多病患在这个时候已经对许多化学疗法产生抗药性。

PurposeThe present study was designed to pursue the kinetic characteristics of acrosome reaction of sperm in the fallopian tube in vivo, to evaluate the effect of human oviductal epithelial cell on the AR capacity of sperm and the possible mechanisms through the application of coculture system with HOEC in vitro.

目的 通过检测与人输卵管上皮细胞共培养的人精子在不同时间的顶体反应率,探讨精子在输卵管内AR过程的特点,分析HOEC对精子AR的影响和可能机制。

The basic structural parameters of pitch2based spherical activated carbon were characterized ,such as specific surface area by BET model , total pore volume , micropore and mesopore volume , sphericity , hardness and content of heavy metal ions . Its adsorption capacity to creatinine and vitamin B 12 , which are typical small and medium toxic molecules in blood , were measured. Hemolysis ratio , number of particles released , pyrexic source and germ count in a man2made kidney made of PSAC were checked .

表征了沥青基球状活性炭的基本结构参数(如比表面积、孔容量、球形度、强度、重金属含量等),测定了其对血液中典型中、小毒性分子的吸附性能(肌酐和VB12 )和溶血反应率,分析了以沥青基球状活性炭为吸附剂的人工炭肾的微粒释放量、热源和细菌含量,并进行临床试验。

The rates of positive reaction to thalassinidea, mussel, and peanut were higher in alimentary allergens. The results were 15.2%, 24.1%, and 16.4%, respectively.

食物性变应原中以海虾、蚌类、花生的阳性与强阳性反应率较高,分别为15.2%、24.1%和16.4%。

Titers and affinity constant of McAb were determined with indirect ELISA, and cross reactivity of McAb with indirect competitive ELISA.

用间接ELISA检测该McAb的效价和亲和性,用间接竞争ELISA检测与其他结构类似物的交叉反应率

The cross reactivity with other SAs was less than 1×10~(-3)%. The affinity constant of the anti-SQ monoclonal antibody SQ_(12)A_(10) was 1.40×10~9L/mol.

经鉴定,三株单抗与其他八种磺胺类药物交叉反应率<1×10~(-3)%,其中SQ_(12)A_(10)单克隆抗体亲和常数为1.40×10~9L/mol,。

The relative cross-reactivity of PA with AFB-1,ZON,T-2,FB were less than 0.01%and with an affinity constant for PA of about 1.54×10~8 liters per mol.It offered a foundation for developing immunoassay method for PA.

单克隆抗体与黄曲霉毒素B1、玉米赤霉烯酮、T-2毒素和伏马毒素B1均无交叉反应率,单抗的亲和常数为1.54x10~8 L/mol,为进一步建立青霉酸的免疫学快速检测方法提供了基础。3。

A competitive ELISA kit for detect ENR was developed with ENR mAb and its traits were tested.Two hybridoma lines were filtered and the best one was 4G1-B3,which secreted ENR mAb with indirect ELISA titers of 1∶1.024×10~6 in ascites.Isotype of the two mAb was IgG_1.ENR mAb had a high affinity constant with 9×10~(10)L/mol.The ENR-Kit had the linear detection range of 0.05~101.6μg/L,the sensitivity of 0.05 μg/L and a good sensitivity with an IC_(50) of 1.1μg/L to ENR,cross-reactivity to other compounds less than 0.01%.The average recoveres of ENR spiked in chicken,liver,fish and milk were 81.5%,87.6%,84.3% and 95% respectively.The coefficient variation was below 10%.

结果表明:筛选出的2株杂交瘤细胞,单抗亚类均为IgG1型,其中4G1-B3株的ENR mAb间接ELISA效价为1:1.024×106,亲和常数为9×1010L/mol;竞争ELISA试剂盒的线性检测范围为0.05~101.6μg/L、灵敏度0.05μg/L、半数抑制浓度(IC50)1.1μg/L,与其他化合物的交叉反应率均小于0.01%,鸡肉样、鸡肝样、鱼肉样和牛奶样的平均添加回收率分别为81.5%8、7.6%、84.3%和95%,不同基质添加恩诺沙星标准品做竞争ELISA对ENR-Kit检测结果影响小,试剂盒保存期6个月以上。

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