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The levels of schistosome circulating cathodic antigen in serum and urine were detected parallelly by McAb-Dot-ELISA. In 81 acute cases, the positive rates in serum and urine were 96.30% and 66.67%(P<0.01) but the combined positive (positive in serum and/or in urine) rate reached 100%, while in 109 chronic cases, they were 77.06% and 10.09%(P<0.01) but the combined positive rate was not increased. In 100 healthy individuals from non-endemic areas, no positives were detected in serum and urine with false positive rate of 0%. The cross reaction rates in serum and urine of 51 cases with clonorchiasis were 9.43% and 0% but all were 0% in 48 cases with ancylostomiasis.

提要 应用McAb-Dot-ELISA平行检测血吸虫病人的血清和尿样(浓缩20倍)中日本血吸虫肠相关趋阴极循环抗原。81例急性血吸虫病患者的血清和尿样的阳性率分别为96.30%和66.67%,而血清和尿样组合检测的阳性检出率提高至100%。109例慢性血吸虫病患者的血清和尿样的阳性检出率分别为77.06%和10.09%,组合检测的阳性检出率没有提高。100份健康人的血清和尿样的假阳性率均为0%。54例华支睾吸虫病患者的血清和尿样的交叉反应率分别为9.43%和0%。48例钩虫病患者的血清和尿样的交叉反应率均为0%。

The limited detectable concentration was 85μg/L. The cross-reaction rate between PAb and other pyrethroid pesticides was low, except deltamethrin.

以抗体与甲氰菊酯的反应率为100%,抗体与其他4种菊酯类农药交叉反应率很低,与溴氰菊酯交叉反应较高。

The overall response rate was 95%, and the complete response rate was 75%.

整体的反应率为95%,而完全反应率为75%。

The results were as follows:(1) The spectral sensitivity response at 14 monochromatic light selected through 340nm to 605nm occurred in curve with multiple peaks, the primary peak in 340nm (ultra-violet) is the highest response rate of phototaxis (21%), the secondary in 524nm, and the rest in 400-440nm and 483nm in order;(2) The response rate of phototaxis is increasing as the relative intensity of light, it is showed as curves with inverse "L" shape in white light and the monochromatic light of 483nm, as an upward ladder at 524nm and a near straight line at 340nm. However, the response rate could be detected at the lowest intensity and not arrived to the summit at the strongest yet;(3) The effect of sex to response to the spectral sensitivity and intensity is not significant;(4) There was not significant photophobism response to light for the ladybird, the behavior probably derived from phototaxis or partly due to random movements. It can be concluded that both the spectrum and intensity of light stimulus gave rise to the phototaxis of P.

结果显示:(1)在340~605nm波谱内其光谱趋光行为反应为多峰型,峰间主次不明显,紫外340nm处峰最高,趋光反应率达21%,其它各峰依大小次序分别位于绿光524nm、蓝光400~440nm和483nm处;(2)随光强增强其趋光反应率增大,白光和483nm刺激时其光强趋光行为反应呈一倒"L"型式样,524nm时呈一阶梯型,340nm时为一较平直的线型;光强最弱时仍均有一定趋光率,最强时均未出现高端平台;(3)性别对其光谱和光强度行为反应均有一定影响,但影响不大;(4)龟纹瓢虫无明显的避光反应,其避光行为可能是趋光行为衍生或其随机活动造成。

The results showed that the population administered with free adjuvant cholera vaccines,both low dose group and common dose group,occurred the weak adverse reaction with 10 ̄25% rate.The reaction rates between two dose groups of the same vaccine have not significant difference;The reaction rate of the first inoculation(19 ̄25%) is higher than those of the second inoculation(10 ̄15%)(P 05);The inoculating local reaction is very light ,only the very few subject occurred the scleroma with 15 mm of diameter.The reaction of aluminum absorbed cholera vaccine is slightly stronger than those of other groups.

结果表明,不加铝佐剂的O139型霍乱菌苗及O1群霍乱菌苗,不论是低剂量组(两剂全程接种45亿菌体)抑或常剂量组(全程接种90亿)接种人群均可产生10~25%的体温呈轻度升高的弱反应,并且同种菌苗的两剂量组的反应率无显著差异;第一剂接种的反应率(19~25%)较第二剂接种的(10~15%)高,P<0.05;接种局部反应轻微,只有个别受试者出现直径小于15mm的硬结;加佐剂的O1群吸附霍乱菌苗的反应较其它组强。

Then the reaction rates of IgE and IgG in asthmatic patients serum to chenopodium album pollen were counted by immunoblotting. RESULTS: Twelve bands of protein were obtained through SDS PAGE. The molecular weight of each band was 92, 63.1, 61, 52, 45, 43, 39.7, 38.9, 34, 31.6, 28.4 and 18.5~12 ku. Immunobloting identified 4 protein bands recognized by sIgE, molecular weights being 92, 34, 31.6 and 18.5~12 ku, which reacted with 70%, 50%, 80% and 90% of asthmatic patient serum.

结果: 藜草花粉经电泳后得到12条蛋白质区带,分子质量依次为92, 63.1, 61, 52, 45, 43, 39.7, 38.9, 34, 31.6, 28.4和18.5~12 ku;免疫印迹可见4条sIgE反应带,蛋白分子质量依次为92, 34, 31.6和18.5~12 ku;与患者血清反应率分别是70%, 50%, 80%和90%;与血清sIgG结合的反应带有8条,蛋白分子质量为92, 61, 52, 45, 43, 39.7, 31.6和18.5~12 ku;与患者血清反应率分别是80%, 40%, 10%, 20%, 80%, 10%, 10%和100%。

Nickel sulfate was the most frequent sensitizer, followed by Thimerosal, Potassium dichromate, Fragrance mix and Formaldehyde. Frequencies of contact allergy to Thiuram mix, Mercapto mix, Imidazolidinyl urea, and bronopol were relatively low.

结果: 1 129 例受试者中,阳性反应747例,阳性反应率较高的变应原依次是:硫酸镍、硫柳汞、重铬酸钾、芳香混合物、甲醛,阳性反应率较低的变应原有:秋兰姆混合物、硫氢基混合物、咪唑烷基尿素、溴硝丙二醇。

Meta-analyses showed that the response rate of TP (topotecan + cisplatin) regimen had no significant difference compared with EP regimen (etoposide + cisplatin) with OR 0.83 and 95%CI 0.63 to 1.09, but myelo-suppression such as leucopenia and thrombopenia was more severe with TP regimen; the response rate of monotherapy with topotecan was similar with that of CE (carboplatin + etoposide) regimen with OR 0.59 and 95%CI 0.22 to 1.60; the response rate of TEP (topotecan + etoposide + cisplatin) regimen was comparable with that of EP regimen with OR 1.37 and 95%CI 0.82 to –2.28, but myelosuppression and anemia were more severe with TEP regimen; the response rate with OR 0.97 and 95%CI 0.60 to –1.57, median time to progression with WMD –2.32 and 95%CI –5.72 to 1.09 and median survival time with WMD –1.65 and 95%CI –7.13 to 3.83 of IV topotecan were similar to those of oral topotecan, while neutropenia was more severe with IV topotecan.

Meta分析结果表明,TP 方案与EP方案的反应率相似 [OR 0.83, 95%CI (0.63,1.09)],但具有相对高的致血小板下降的骨髓毒性;单药拓朴替康与CE方案的反应率相似 [OR 0.59, 95%CI (0.22,1.60)];TEP方案(拓扑替康+足叶乙甙+顺铂)与EP方案的反应率相似 [OR 1.37, 95%CI (0.82,2.28)],TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案;口服拓扑替康与静脉滴注拓扑替康的化疗后反应率 [OR 0.97, 95%CI (0.60,1.57)]、中位疾病进展期 [WMD –2.32, 95%CI (–5.72, 1.09)]、中位生存期 [WMD –1.65, 95%CI (–7.13,3.83)] 相似,口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

Meta-analysis based on included studies showed that response rate of TP regimen has no statistic significance compared with EP regimen[OR0.83,95%CI(0.63-1.090)],but myelo-suppression such as leucopenia and thrombopenia is more severe; response rate of single topotecan has no statistic significance compared with CE regimen[OR0.59,95%CI(0.22-1.60)]; response rate of TEP regimen has no statistic significance compared with EP regimen [OR1.37, 95%CI(0.82-2.28)], but myelo-suppression such as leucopenia, thrombopenia and anemia is more severe; response rate of IV topotecan has no statistic significance compared with Oral topotecan[OR0.97, 95%CI(0.60-1.57)],so as median time to progression[WMD-2.32, 95%CI(-5.72,1.09)] and median survival time[WMD-1.65, 95%CI(-7.13,3.83)],while neutropenia is more sever in IV topotecan than Oral topotecan.

分析表明,TP方案与EP方案的反应率相似[OR0.83,95%CI(0.63-1.090)],但具有相对高的致白细胞和血小板下降的骨髓毒性;单药拓扑替康与CE方案的反应率相似[OR0.59,95%CI(0.22-1.60)];TEP方案与EP方案的反应率相似[OR1.37,95%CI(0.82-2.28)],TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案;口服拓扑替康与静脉滴注拓扑替康的化疗后反应率[OR0.97,95%CI(0.60-1.57)]、中位疾病进展期[WMD-2.32,95%CI(-5.72,1.09)]、中位生存期[WMD-1.65,95%CI(-7.13,3.83)]相似,口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

This reaction model can be used in coarse mesh as compared with other reaction model.

与其他反应率模型相比,这种反应率模型可以应用于较粗的网格。

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