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We show that in mammalian cells, the Sir2 homolog SIRT1 appears to control the cellular response to stress by regulating the FOXO family of Forkhead transcription factors, a family of proteins that function as sensors of the insulin signaling pathway and as regulators of organismal longevity.

在哺乳动物Sir2同源物SIRT1似乎通过调节FOXO Forkhead转录因子家族来控制细胞对应激的反应,该转录因子家族可以作为胰岛素信号转导的传感器和生物寿命的调节因子。

Any consequence of a response that increases the frequency of that response.

增加反应发生的可能性或频度的任何刺激物。

The mechanism of color changes between Fuchsine Acid and Bovine Serum Albumin was studied by spectra probe. And the influence of different experimental conditions on the absorption spectra of FA-BSA mixtures was investigated.

摘 要:利用光谱探针技术研究了酸性品红(Fuchsine Acid,FA)与牛血清白蛋白(Bovine Serum Albumin,BSA)的变色反应机理,考察了不同实验条件对FA-BSA复合物吸收光谱的影响。

To elucidate the relationship of GSE expression and gametogenesis, mRNA (0.5μg each) from mouse testis and ovary on different postnatal days were analyzed by RT-PCR with specific primers for GSE cDNA. The GSE mRNA in the testis of mouse was first detected at Day 14 postpartum, when cells at mid-pachytene are likely to appear.

为了阐明GSE表达与配子发生的关系,从0~49日龄小鼠睾丸和卵巢中提取mRNA(每样品0.5μg,将其与特定的GSE cDNA引物进行RT-PCR反应,分析的结果发现,GSE mRNA在出生后第14天的小鼠睾丸中首先被检测到,这一时间正是中粗线期精母细胞很可能出现的时期。

In ovary, PNA receptors appeared in the oocyte cytoplasm of second phases of oogenesis; the positive granules gradually increased from third to forth phases, and they exhibit a maximum expression before vitellogennic stage in cytoplasm of oocyte; from vitellogennic stage to chorionation stage, the positive granules gradually reduced. Binding sites on follicle cells were changed with their morphological variation in every stage of oogenesis.The staged and specific expression of oncogene c-kit, the tyrosine-kinase receptor, is closely related with gametogenesis.

2在中华蚱蜢卵子发生的早期,PNA受体是由卵母细胞自身合成;在卵黄发生前的准备时期,卵母细胞质中的PNA受体一部分来源于自身合成,另一部分则来源于滤泡细胞,而糖复合物的大量出现可能直接与卵黄发生有关;卵黄发生期PNA受体的减少可能是在卵黄物质形成中部分发生了修饰;卵黄和卵壳的相继形成过程中,阳性反应的出现说明PNA受体参与了卵黄膜及卵壳的形成,而这些受体物质是由滤泡细胞分泌的。

Coli mainly in a form of inclusion body. The expressed product contained about 25% of total somatic protein and showed good reactogenicity as proved by Western blot. The IgG level against GAMP induced by GAMP-CRM197 conjugate was significantly higher than those by GAMP and by the mixture of CAMP and rCRM197. Repeated immunization with the conjugate induced immunopotentiation, indicating the effect of CRM197 as a carrier protein.

结果重组CRM197在大肠杆菌中主要以包涵体形式表达,表达量占菌体总蛋白的25%左右;Western blot证明重组rCRM197具有良好的反应原性;各针接种后,结合物诱生的多糖特异性IgG水平均显著高于GAMP组和GAMP+rCRM197混合物组,具有较强的免疫原性;多次接种产生了免疫增强效应,重组CRM197具有载体蛋白的作用。

This process was studied by following the substrate reaction of GPa in this paper.

本文第五章用底物反应动力学的方法研究了糖原磷酸化酶的磷酸化过程。

Nicotianamine synthase gene has an important function in the Fe-deficiency response of graminaceous monocots, and it catalyzes substance to nicotianamine which plays an important carrier in the internal transport of Fe(superscript 2+) and other divalent metal ions. Nicotianamine can bind with Fe(superscript 2+) to form Fe(superscript 2+)-NA complex and protect plants from toxicity in acidic soil.

烟酰胺合成酶基因在单子叶禾本科的缺铁胁迫应答反应中起着关键作用,它的催化产物烟酰胺是铁及其他二价金属离子在体内吸收和转运的重要载体,且能与Fe(上标 2+)结合形成Fe(上标 2+)-NA复合物,从而使植物在酸性土壤中免受铁毒害。

The polymerization of styrene were catalyzed by the schiff base metal complexes / Grignard Reagent catalytic system.

用合成出的西佛碱金属配合物与助催化剂格氏试剂组成催化体系,系统研究了这种新型催化体系对苯乙烯的催化聚合反应的规律。

In Chapter 3 and Chapter 4, this kinetic method was applied to the studies of inactivation kinetics of Chinese hamster dihydrofolate reductase by urea or guanidine hydrochloride.

在第三、四两章中,我们将酶活性不可逆抑制底物反应动力学理论应用于中华仓鼠二氢叶酸还原酶的脲和盐酸胍失活动力学研究。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。