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Starting from boldine (56), secoboldine (57) was prepared by ring opening at N6 position. Then the resulting secondary amine, secoboldine (57), was treated with various substituted benzaldehydes, to form a series of diarybutanoid-like tertiary amine alkaloids.

以波尔定碱(boldine, 56)做起始物,在N 6位置做开环反应可以得到次波尔定碱(secoboldine, 57),再用还原胺化反应在二级胺上接上不同的苯醛,可以得到一系列的三级胺生物碱化合物。

The thermal reaction of Karamay residue oil with three kinds of fine carbonous particle additives was carried out in a batch reactor under N 2 atmosphere to investigate the effect of additives on coke formation .

在高压反应釜中研究了三种不同碳质颗粒添加物对克拉玛依常压渣油420℃氮气气氛下热反应生焦的影响。

Eighteen SSR primer pairs were designed and synthesized.The factors which affected on the SSR reaction of Toona ciliata var.

利用所合成的引物优化SSR反应体系,对影响SSR反应的各个因子进行了探讨。

Three reservoir clay minerals such as montmorillonite, kaolinite and illite were selected. Alkali consumption was investigated to define coeffect between these minerals and their corresponding mixtures under three amount ratios, solid/liquid ratios, and at different temperature conditions.

选择蒙脱石,高岭石,伊利石等三种在储层中最常见的储层粘土矿物,两两分别按2:0,1:1,0:2质量配比组成复配物系列;在30℃、50℃温度下按1:5,1:8,1:10固/液比分别与1.6%的Na2CO3溶液反应8h、120h、360h;监测反应前后碱液浓度的变化;计算了各条件下各自的绝对碱耗量。

Imatinib, a BCR-ABL tyrosine kinase inhibitor, is able to induce a complete cytogenetic response in more than 85% of patients with CML. However, the researchers note that patients with a complete cytogenic response tend to relapse when imatinib is discontinued, and less than 10% of patients achieve a molecular remission, defined by an undetectable residual disease using real-time quantitative–polymerase chain reaction.

Imatinib是一种BCR-ABL酪胺酸激酶抑制物,可以在85%以上的CML病患诱导完整的细胞生成反应;不过,研究者指出,完整细胞生成反应的病患倾向在停用imatinib时复发,不到10%的病患达到分子生物学上的缓解,其定义为以即时定量聚合酶连锁反应侦测不出残余疾病。

Imatinib, a BCR-ABL tyrosine kinase inhibitor, is able to induce a complete cytogenetic response in more than 85% of patients with CML. However, the researchers note that patients with a complete cytogenic response tend to relapse when imatinib is discontinued, and less than 10% of patients achieve a molecular remission, defined by an undetectable residual disease using real-time quantitative–polymerase chain reaction.

Imatinib是一种BCR-ABL酪胺酸激酶抑制物,可以在85%以上的CML病患诱导完整的细胞生成反应;不过,研究者指出,完整细胞生成反应的病患倾向在停用imatinib时復发,不到10%的病患达到分子生物学上的缓解,其定义为以即时定量聚合酶连锁反应侦测不出残餘疾病。

The catalytic action of various kinds of functional coordination compound and metallomicelles which are made from the complex and micelle, as mimic hydrolase or peroxidase, have been studied respectively in catalyzing the carboxylic ester and phosphatic diester hydrolysis, and the phenolic derivant oxidation in this paper. Some novel results of academic significance have been obtained.

本文以不同类型的功能配合物及其与表面活性剂形成的金属胶束作为水解酶和过氧化物酶的模拟酶模型,分别研究它们对羧酸酯、磷酸二酯水解反应和酚类氧化反应的催化作用,取得了新的有学术意义的成果。

The first asymmetric synthesis of trans-β-hydroxy-γ-butyrolactones:-(3R, 4R, 5S)-4-(1-acetoxy-isopropyl)-3-hydroxy-butyrolactone 65a was achieved starting from isobutylaldehyde through nine steps. The key steps involve the construction of three chiral carbon centers by the Sharpless's asymmetric epoxidation and Substrate directable chemical reaction.

以异丁醛为起始原料,经过九步反应首次设计合成了具有三个手性中心的trans-β-羟基-γ-丁内酯:-(3R,4〓,5S)-4-(1-乙酰氧基-异丙基)-3-羟基-丁内酯65a,关键步骤是Sharpless不对称环氧化和底物定向不对称合成反应。

The results lent support to the concerted electron-hydrogen atom transfer mechanism for the formal hydride transfer in BNAH mediated reductions of activated ethylenic compounds.

我们也把反应的底物进行了拓展,对反应的机理进行了研究,找到了更多的证据说明了部分协同的电子转移和氢原子转移机理是存在的。

Analogous complexes 3a" and 4a"= CpRu(PPh32, Ar = para-C6H4OMe containing methoxy group at the para-position of gem-diphenyl group were similarly obtained from protonation of the corresponding acetylide complexes via formation of vinylidene intermediate. But only complex 3a'= CpRu(PPh32, Ar2 = fluorenyl is stable in solution, and decomposed to unidentified complex when heated to reflux in THF. Deprotonation of complex 4a in the presence of base gives neutral acetylide complex 6a.

在两个相邻位置的苯基对位位置上接有一甲氧基的衍生物3a&和4a&也可利用类似的质子化反应合成,唯有错合物3a'= CpRu(PPh32, Ar2 = fluorenyl 可以稳定於溶液中,不会进行上述反应,如将其溶於四氢呋喃溶液加热至沸腾则会分解产生无法鉴定的化合物。

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