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We further evaluated the synergistic cytotoxicity of TRAIL in combination with actinomycin D, cisplatin and paclitaxel in A549 cell lines in vitro and in vivo.

本实验选择了人肺腺癌A549细胞瘤株作为我们实验研究的对象,通过TRAIL对人肺腺癌A549细胞诱导凋亡研究,在A549的荷瘤裸鼠的动物模型上研究了其体内的抗肿瘤活性,并进一步研究了TRAIL与化疗药物放线菌素D(actinomycin D,Act D)、紫杉醇和顺铂(cisplatin,CDDP)的联合作用对人肺腺癌A549细胞的体外协同抗肿瘤活性,通过化疗药物协同增强TRAIL抗肿瘤活性作用机制的初步研究,为降低临床化疗药的用药量,减轻其对机体的不良反应提供一定的理论基础。

It can be demonstrated that Yichuanping capsule has the inhibiting effect on AHR in asthma, and one of mechanisms is refraining the production of ET1 and NO by airway epithelium.

易喘平胶囊对哮喘气道高反应性具有一定的抑制作用,降低气道上皮细胞分泌ET1和NO是这种作用发挥的机制之一。

Degradation of long residual herbicides and antidotal effective of TNA were tested by means of using bioassay methods combined in greenhouse and field test.

利用生物化学的方法研究谷胱甘肽转移酶、乙酰乳酸合酶、苯丙氨酸解氨酶和超氧化物歧化酶在除草剂作用下的反应和作保灵对相关酶、GSH,脯氨酸和多酚含量调控作用。

Caffeine - A derivative of coffee, is an efficient arouser of central nervous system capable to drive away fatigue, and improve renal circulation. Its stimulation on the cerebral cortex activates Neurotransmitter receptors in the cell membrane; the adenylyl cyclaseactivated on the other surface of the cell catalyzes Adenosine Triphosphate, forming Cyclic adenosine monophosphate, and thus set off series of bio-chemical reactions, like increase of passionate feel, prompt recovery from fatigue after working etc..

咖啡因—由于咖啡本身具有兴奋神经中枢,消除疲劳,增加肾脏血流量的作用,通过对大脑皮层的刺激,使神经递质作用于细胞膜受体,激活了膜另一侧的腺苷酸环化酶,被激活的腺苷酸环化酶催化三磷酸腺苷环化酶,被激活的腺苷酸环化酶催化三磷酸腺苷形成环磷酸腺苷,从而引起一系列生化反应,如增加愉快感和消除事后疲劳等。

Mechanism of carbon combustion reaction is deduced based on the flame temperature produced by coke burning in bloomery abdomen.

本文根据炼铁高炉炉腹内焦炭燃烧产生的火焰温度推测碳燃烧反应的机理为:第一步,氧气吸收光子形成游离态氧原子,每摩尔氧气吸收 1mol光子;第二步,碳与游离态氧原子作用生成CO ,每生成 1molCO发出 1mol光子;第三步,CO与氧分子作用生成CO2 ,该步骤既不吸收光子,也不发出光子。

Because the rate of ET and HT reactions is determined by the coupling term J, and in long range ET and HT systems the degeneracy of the π orbitals of donor and acceptor is lifted through mixing with the bridge orbitals of appropriate symmetry by an amount △E. Because the △E splittings are proportional to electronic coupling, so we can use the static quantity △E to exploring the dynamic quantity J, and to make a detailed study on the microscopic influence of coupling mechanism in ET and HT process.

由于电子转移和空穴转移反应速率的大小决定于反应的耦合因子,在长程电子转移和空穴转移体系中,给体和受体的简并π轨道由于与饱和桥之间的TB作用而产生一定的分裂能,此分裂能又与耦合因子的数值成正比,因此,我们可以用静态的分裂能数值间接地表征动态的耦合因子,从而详细研究电子转移和空穴转移过程中耦合机理的微观影响因素。

The following main results are obtained: The TiO_2 photocatalyst with small crystallite size, high surface area, narrow and uniform pore size distribution, and microporous frameworks could be prepared out by applying MW radiation in the preparation process. The microwave-induced fluorescence technique verified for the first time that microwave enhanced the formation rate of hydroxyl radical, leading to the increase in the photocatalytic efficiency. Compared with the conventional catalyst, TiO_2 prepared by MW dielectric heating owns a higher UV absorption ability, and its optical absorption edge and photovoltaic response are shifted toward the short wavelength region, resulting in increase of photooxidation efficiency. The photocatalytic conversion and the mineralization ratio of acetaldehyde are increased respectively by 30% and 40% over the TiO2 prepared by MW radiation when compared to the TiO2 prepared by the conventional heating. For the MW-assisted photocatalytic reaction over the MW-prepared TiO2, production of hydroxyl radicals is enhanced by 22.5%, and the photocatalytic conversion is accordingly increased by 20%. Similarlly, applying MW also increased the photocatalytic conversion and the mineralization ratio of acetaldehyde over TiO2/Al2O3 sample.

论文得到如下主要结果和结论:(1)微波介电加热TiO_2 溶胶可得到晶粒度小、光催化活性高、比表面积大和孔径分布窄而均一,且微孔发达的TiO_2光催化剂;在溶胶干燥处理过程中微波可使催化剂表面缺陷增加,进而导致光催化反应过程有更多的活性羟基自由基产生;(2)微波制备能显著增强TiO_2 样品的紫外光吸收率,并使其光吸收和光伏响应阈值发生蓝移,从而提高TiO_2的氧化还原能力;(3)与常规加热法所制TiO_2比较,微波法制备的TiO_2对乙醛的光催化降解转化率提高30%,CO_2生成率提高40%以上;(4)与未加微波辐射时相比,发现在光催化反应过程中施加微波,TiO_2 的羟基自由基生成速率提高了22.5%,相应CH_3CHO 光催化降解转化率提高了20%;对Al_2O_3/TiO_2催化剂,CH_3CHO 光催化降解转化率甚至提高了33%,同时CO_2 的生成率也都大幅度提高;(5)微波辐射可改变光催化降解乙醛的产物分布,推断施加微波时乙醛光催化降解按照羟基自由基引发的链式反应机理进行,微波&非热效应&起主要作用。

Psychology of a conditioned response; caused to die out because of the absence or withdrawal of reinforcement.

指一种条件反应;因为强化作用的消失或者减弱而导致条件反应的渐渐消失。

Single component and multi\|component of iron system colloidal catalyst \Ali\|Bu\-3CH\-2CHCH\-2Cl\ were mixed by different ratios in hydrogenated gasoline medium at 25℃.This paper studied the relationship between the nonaqueous systematic electroconductivity and the concentration of catalyst components.In combination with Tyndall effect,polymerization experimental results,Ali\|Bu\-3 existed in associated state and dissociated into ionpair.The reaction between Ali\|Bu\-3 and Fenaph\-2 was the main reaction which formed colloidal core.Ali\|Bu\-3 reacted on CH\-2CHCH\-2Cl and Ali\|Bu\-2Cl was yielded which joined the formation of active center on the surface of colloidal core.The excessive Ali\|Bu\-3 was dissociated into ionpair which formed double electrode layer,and the double electrode layer kept the colloidal particles relatively stable.

研究了在25℃加氢汽油介质中,铁系胶体催化剂[Fenaph2Ali-Bu3―CH2==CHCH2Cl]单组分、多组分按不同配比混合,非水体系电导率与浓度的关系,结合Tyndall效应,聚合实验结果,得出Ali-Bu3以缔合状态存在并解离成离子对它同环烷酸亚铁的作用是形成胶核的主要反应,与氯丙烯反应生成的氯化异丁基铝,在胶核表面参与形成活性中心由过量Ali-Bu3解离的离子对形成的双电层结构,使胶粒保持相对稳定。

The rate enhancement in homogeneous Suzuki reaction by Lewis acid has been investigated.

研究了Lewis酸在Suzuki反应中的促进作用,考察了Lewis酸、溶剂及碱性试剂对目的产物收率的影响,并优化了反应条件。

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