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The goal of this study was to compare long-term health outcomes and mortality after oophorectomy or ovarian conservation in 29,380 women participants of the Nurses' Health Study who had a hysterectomy for benign disease. Of these, 16,345 (55.6%) had hysterectomy with bilateral oophorectomy, and 13,035 (44.4%) had hysterectomy with ovarian conservation.

这项研究的目的在於比较卵巢切除术或是卵巢保留,对参与护理人员健康研究之29,380位因良性原因切除子宫之女性的影响;在这些病患中,16,345位(55.6%)接受子宫摘除与双侧卵巢切除,而13,035位(44.4%)接受子宫摘除与卵巢保留。

D. Bimanual examination confirms uterine position and size, and uterine sounding confirms the direction of the endocervical canal.

d。双合诊检查确定子宫的位置和大小,探宫腔确定宫颈管的方向。

D. Bimanual examination confirms uterine position and size, anduterine sounding confirms the direction of the endocervicalcanal.

d。双合诊检查确定子宫的位置和大小,探宫腔确定宫颈管的方向。

Widely separated and loosely clustered irregular but branched glands embedded in broad zones of cellular myofibromatous stroma to those possessing crowded, markedly complex, branching glands separated by sparse intersecting fascicles of fibromuscular tissue.

显微镜下的特点是双相增生,两种成份,子宫内膜腺体和细胞呈非典型性增生,还有子宫肌瘤样间质成份,子宫肌瘤样间质成份弥漫分隔松散的,成片状排列,但不规则的分技状子宫内膜样腺体,这些腺体也可以呈拥挤的,明显复杂性增生。

Methods 30 patients with various kinds of uterus tumor and postpartum hemorrhea were treated with uterus arterial embolism with PVA microparticle whose diameter was 300~500 μm, iodized oil emulsion and/or gelatin sponge stick through super-selectivity unilateral or bilateral uterus arte.

方法对30例各类子宫肿瘤和产后大出血患者,通过超选择性双侧或单侧子宫动脉插管,用直径300~500μm的PVA微粒、碘油乳剂和/或明胶海绵条将子宫动脉栓塞。

Objective To investigate the relation of the position of double-lumen balloon catheter and the failure to display the homolateral oviduct in Hystersalpingography.

在使用双腔球囊导管行子宫输卵管造影(hys-terosalpingography,HSG)159例检查中,偶尔见到少数病例的导管顶端紧靠一侧子宫角部,该侧输卵管未能显示。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病,不管是急性淋巴性白血病或是急性骨髓性白血病,在染色体11q23部位有染色体易位的情况;这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是,单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%;并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且,这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后,而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖,遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以,白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

The pathological state in rats with uterine leiomyoma is marked by the high levels of sex steroids, low immune function. The cells of uterine unstriated muscle were in a state of distinct proliferation and activity. Double Modle Method was better than Single Modle Method by comprehensive evaluation.

结果 两种方法均能制备子宫肌瘤大鼠模型,子宫肌瘤大鼠出现血清性激素水平升高、免疫功能低下及肌细胞高度增生活跃的病理状态,综合评价双模法优于单模法。

Objective To explore possibility and efficacy of two side round ligaments suspended crossly tow side uterosacral ligaments for uterine prolapse of reserve cervices or uterines.

导读:目的探讨双侧圆韧带交叉悬吊双侧子宫骶骨韧带治疗子宫脱垂的可行性及疗效。

After bilateral dissection of internal and external iliac vessels, the transplanted uterus was placed in orthotopic position, the cervix was sutured to the vaginal vault, uterosacral ligament was reconstructed and extended, uterine vessels were anastomosed to respective external iliac veins and arteries.

经过清理双侧髂内血管和髂外血管,移植的子宫被放置在原来的正常位置。医生对患者的子宫颈与阴道穹窿进行了缝合,又重建并延伸了子宫骶韧带,同时将子宫血管分别与髂外静脉和髂外动脉进行缝合。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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