及物地

Research usejP.Haggett"s pattern of spatial structure and system, analysis technique of tourism market space and data of spot check to analyze the evolvement of spatial structure and problems of tourism development from six faces, move, path, crunode, significance of crunode, ground and diffuse. The law of the evolvement of spatial structure: First, tourism development keeps rising. Second, AR of xi"an is very big and stable, Xi"an is tourism hotspot and center. Third, origin market space sticks out east, and isn"t continuous. Fourth, tourist proportion of XAZ follows the low of distance decay. Distance decay is very obvious in adjacent zone because of little attraction. Sixth, the spatial distribution of tourist origins has become less concentrated. Tourist origins of east China develop quickly. Three problems: First, tourism development is very unbalance between Xian and its adjacent zone.

西安及毗邻地区的国内客源市场空间结构的研究，采用了英国著名地理学家哈格特描述的空间结构模式与秩序，利用旅游市场空间分析技术，借助市场抽样调查、数量分析，从运动模式、路径、结点、结点层次、地面和扩散6个层方面进行了剖析，归纳总结出5个客源市场空间结构演变规律：(1)旅游业发展整体保持增长趋势；(2)客源吸引半径大而稳定，西安市是全国性的旅游热点城市和旅游中心城市；(3)客源市场分布突向东部，呈不连续分布；(4)游客比重的距离衰减普遍存在，毗邻地区吸引物及自然吸引物吸引力较小，距离率减明显；(5)客源集中度减小，客源市场发展呈现跳跃式增长的演变规律。3个市场拓展面临的问题：(1)西安与毗邻地区间旅游业发展不平衡现象明显；(2)客源市场区位不佳；(3)旅游产品单一老化，类型单调乏味。

The deformation mechanism is mainly the single-slip and cross-ship, the fracture mechanism is mainly the congregation of transgranular micro-hole, and large uniform deformation occurred before tough fracture, and therefore, the ability of plastic deformation and the mechanical properties of the material were remarkably improved. These fully indicate that the new melt-treatment developed in this work is an effective and advanced technique, and further testify that the improvement of metallurgical quality of the material is the key to enhance its mechanical properties, especially its plastic deformation performance. The results of tensile and compression tests at elevated temperature also indicate that the suitable hot-working temperature range is 400～450℃. 4. A steady-state plastic flow exists during the plastic deformation of the aluminum sheet used for pressure can at elevated temperature. A hyperbolic sine relationship can be satisfied between the steady-state flow stress and strain rate by introducing an Arrhenius term which involves some thermal activation parameters, i.

压力罐用铝材中的主要冶金缺陷为Al〓O〓夹杂物、气孔及富Fe杂质相；高效熔体处理显著改善了材料的冶金缺陷的存在形态，使含杂量明显减少、夹杂物尺寸变细小且分布均匀，富Fe杂质相变为细小、分布均匀的团球状或短棒状的复杂化合物，同时也明显细化了结晶组织；此外，由于高效熔体处理有效地减少了材料中裂纹萌生源数量，因而改变了材料的塑性变形微观过程及断裂方式，主要以单滑移和交滑移进行塑性变形，断裂方式为穿晶微孔聚集型，韧性断裂前产生了大量的均匀变形，不易出现变形失稳，从而显著提高了罐用铝材的塑变能力和力学性能。

The Diels-Alder cycloadditions of [60] fullerene for preparation of optical limitingmaterials are discussed in chapter 3 and 6. Soluble cycloaddition derivatives of 〓aresynthesized by the reaction of 〓 with indene,1,1'-biindene andcyclopentadiene derivatives.〓Particular, the Diels-Alder cycloaddition of 〓 with1,1'-biindene under controlled conditions affords the stable monoadduct 〓〓of novel structure, which was confirmed by HPLC, FTIR, FD-MS,〓NMR,〓 NMR, HMQC and HMBC spectra, Its two bridgehead cage carbons resonate at70.91ppm, The 〓 NMR spectra showed 38 lines consistent with the 〓 symmetryassociated with [6,6] addition. The 〓 shows similar optical limitingproperties to that of 〓 in toluene for 8ns laser at wave length 532nm. Moreover, thehigh solubility of this adduct in polar solvents such as THF, acetone enables itsincorporation into sol-gel glass matrix. The thin films prepared via the sol-gel methodshow improved OL behaviour compared to those of 〓. The langmuir-Blodgett filmformation and uv-visible absorption of 〓 are also investigated. LBmonolayer of this compound is prepared on the air-water interface at 〓 mol/l. In chapter 4, three water-soluble derivatives of [60] fullerene: fullerol(1), theaddition product (2)of fullerol (1)with polyvinylpyrrolidone and fumaric acidderivative of 〓(3) are synthesized and characterized.

通过Diels-Alder环加成反应，用茚〓和1，1'-联茚〓及取代茂合成了一系列可溶性的〓环加成衍生物，发现可控制反应条件，使1，1'-联茚与〓反应，并高产率地得到具有新颖结构的单加成物，用HPLC、FTIR、FD-MS 及〓、HMQC、HMBC等多种波谱技术对其结构进行表征，测得它的两个〓杂化的桥头碳的化学位移为〓ppm，证明生成的衍生物为6∶6闭式环加成，〓NMR谱中共给出38个信号，表明〓联茚衍生物分子具有〓对称性；在波长532nm，脉冲宽度8ns的激光下，〓联茚衍生物的甲苯溶液的光限幅性能与〓的甲苯溶液相近，由于〓联茚单加成衍生物熱稳定性好，在四氢呋喃，丙酮等极性溶剂中溶解性好，能分别均匀地掺入溶胶-凝胶中，已发现它的溶胶(so1)光限幅性能优于纯〓的光限幅性能；使用Langmuir-Blodgett技术将〓联茚衍生物在空气和水的界面进行了LB单层膜和多层膜实验以及UV-Vis吸收谱研究，通过等温压缩曲线测试，证明浓度为〓〓时，〓联茚衍生物能够形成单层膜。

Functional requirements of habitat for these two species, expressed as habitat suitability and marginal density efficiency, and factors reflecting human disturbances such as the weighted road density and buildup density, were used in the calculation of a cost surface for Least Cost Analysis.

因此挑选杂食性的台湾黑熊及草食性的台湾长鬃山羊为目标物种，利用物种对於两个栖地因子（栖地适宜度、边际密度效应）及人为干扰因子（道路加权密度、建物密度）的反应强弱，制作成本曲面图。

Degradation test in vitro was carried out in phosphate buffer solution (0.1M, pH7. 4) at 37 ℃. The buffer solution was changed daily. Degradation test in vivo was implanted the sample to subdermal in adult ICH rat in the scapular area lateral to the dorsal midline. At suitable time the samples were recovered. Molecular weight changes in surface layer and bulk of polymer sample were measured by GPC and weight loss was determined gravimetrically. It was found that the degradation behavior can be regulated by changing the composition of copolymers. The critical compositions from surface to bulk degradation behavior for PGCA, PLCA, PLMCA, PLDCA systems were 15-20, 20-30, 30- 40, 40 of mol percent GA or LA unit in copolymers, respectively. The degradation behavior of PGCA, PLCA, PLMCA, PLDCA systems were compared and analysed. Some factors influencing the degradation character, such as copolymer composition, hydrophobicity, crystallinity and enzyme affect etc. played important role.

体外实验中材料降解环境为37℃，0.1M，pH7.4磷酸缓冲溶液，每天换液，定期取样；体内实验中将聚合物试样埋置于ICH小白鼠背部肩胛骨皮下部位，定期处死小鼠，取样，将体内体外样品进行重量损失及试样内外层分子量变化测定，分析各聚合物试样降解行为特性，实验结果证明，改变共聚物组成，可以调节各聚合体系降解行为特性，对PGCA，PLCA，PLMCA，PLDCA共聚体系，交酯摩尔百分含量15-20％，20-30％，30-40％，40％分别为各体系内降解行为特性由表面降解型向本体降解型过渡的临界转折点，交酯含量较低的聚合物不同程度地表现表面降解行为特性，论文对各共聚体系体内外降解行为作了分析对照，例如共聚物组成对材料降解速度与降解行为的影响；生物体内酶对降解行为的影响；材料亲疏水性，聚合物链段结晶行为及碳酸酯结构对材料降解行为的影响等，得出交酯/环碳酸酯共聚体系降解行为一些共性和规律。

These compounds are of substantial interest both inviewpoints of theory and practical applications, mainlyunder the stimulus to achieve synthetic models either foractive sites of iron-sulfur proteins or for transitionmetal catalysts. This thesis describes the synthesis, structures andconformations of 51 new iron-sulfur cluster complexes,which have been characterized by elemental analysis andstandard spectroscopic methods. In addition, single-crystalX-ray diffraction analyses were performed for 4 representa-tive new compounds. Reactivities of μ-〓 with mono- and di- Grig-nard reagents derived intermediates toward various organicelectrophilic substrates were studied, along with complexa-tion of arynyl-containing iron-sulfur clusters by 〓Thus, several bridged, non-bridged, monomeric, dimeric,homonuclear, heteronuclear iron-sullfur and iron-sulfur co-balt-carbon cluster complexes were synthesized. A novelreaction and convenient route for the synthesis in highyield of tetranuclear iron complexes 〓 containing atetracoordinated sulfur atom was discovered, whereas aplausible mechanism based on experimental results was propo-sed for the formation of the new cluster type.

鉴于有机铁硫原子簇化学在基础理论发展和应用方面的重要意义，因此我们开展了这一课题的研究，并取得以下主要成果： 1、本文共合成了51个新有机铁硫及含钴碳簇基的有机铁硫原子簇配合物，除用元素分析，NMR，IR，MS法表征其结构和构象外，还用X-光衍射技术测得四个代表性配合物的单晶结构和构象； 2、我们业已发现炔基Grignard试剂同〓可形成一种&开环&与&闭环&中间物的平衡混合物，研究该平衡混合物同各种亲电试剂的反应； 3、研究发现了一种可高产率地形成〓含〓四配位硫挛合簇的新化学反应并对此反应提出了—种有趣的反应机理； 4、首次由1，4-二溴丁烷双Grignard试剂与〓制得一种新型铁硫簇双硫阴离子活性中间体，并进而研究了它的亲核反应性能； 5、找到了通过〓的光化学反应来合成簇合物〓-〓的一条有实用价值的新路线。

The nanoplex were smaller than the unmodified nHAP; thelipiodol/nanoplex emulsion, with the mean diameter at 75±11.8nm can disperse moreuniformly and be more soluble and stable, contrary to the unmodified nHAP and nanoplex Conclusion: Nanoplex/pDNA mass ratios greater than 15 had exhibited completepDNA absorption onto positive charged polyplex and pDNA protection from thedestruction of nucleinase in rabbit serum. Unmodified nHAP may can\'t induce effectivegene delivery.PartⅡThe construction of the recombint eukaryotic expressive vector ofwild-type human p53 and RbObjective: To construct the recombint eukaryotic expressive vector of wild-type humanp53 and Rb by utilizing the theory of molecular medicine.

结果nHAP颗粒本身大小小于100nm，但由于颗粒表面本身带负电，不能包括有效地结合及保护DNA；经Ca~(2+)修饰后，颗粒可带正电，可一定程度地结合和保护DNA，但聚合物本身的中性电与带负电的细胞膜结合，而且本身的颗粒则变地容易聚集而成为很大的颗粒，也不利于细胞的吞噬；经PLL修饰后，颗粒溶解性提高，直径变小，表面带正电，电泳结果显示PLL-nHAP颗粒可包括有效地结合和保护DNA免受兔血清的破坏，而且复合物表面的正电也包括有利于与细胞膜的结合与吞噬。

Our report is of the first description of the fatty acid amide and fatty nitrile in the paleolake sediments and provides the basis for the nitrogen-containing lipids investigation in lake sediments.

本文首次在古湖相沉积物中报道了系列脂肪酸酰胺分子化石及系列脂肪腈化合物这两类物质，为我们更好地理解含氮类脂物分子化石在湖泊沉积物中的转化过程提供了一定的理论依据。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池，将lipid A包被于非衍生样品池，分别建立以PGN、CpG DNA及lipid A为靶点的技术平台，对114种抗炎中药水提物进行筛选、评价其活性物质含量，并评估出针对上述三种病原分子均具有较高结合活性的中药；(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术，从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分；在体外实验中，测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力；MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响；ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用；在体内实验中，采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌，建立细菌脓毒症小鼠模型，观察活性组分对脓毒症模型小鼠的保护作用。

Having MREE enrichment and evident minus-abnormity of cerium, the total REE in south coral reefs sediments is largely lower than that in other ocean zones, which indicate the dominately biologic sources of the sediment.

3铅同位素组成及三维拓扑投影矢量V_1、V_2值示踪结果显示：东北部海域沉积物铅同位素组成与珠江、华南地体的铅同位素组成及V_1、V_2值范围一致，反映其物源主要是珠江以及经台湾海峡输入的华南陆源物质。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。