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去甲肾上腺素

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MAIN OUTCOME MEASURES: The contents of monoamine neurotranmitters of norepinephrine, adrenalin, dopamine and 5-serotonin (5-HA) and its metabolites of DHPR, 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid in the striatum and marginal area of brain in rats were observed.

主要观察指标:大鼠纹状体和脑边缘区单胺类递质去甲肾上腺素、肾上腺素、多巴胺和5-羟色胺及其代谢产物3,4-二羟苯乙二醇、5-羟吲哚乙酸、高香草酸的含量。

MAIN OUTCOME MEASURES: Content of monoamine transmitter such as levarterenol, adnephrin, dopamine, indoleacetic acid, homovanillic acid and 5-serotonin.

主要观察指标:测定各组大鼠脑组织单胺类神经递质去甲肾上腺素、肾上腺素、多巴胺、吲哚乙酸、高香草酸和5-羟色胺的含量,并进行组间对比。

Venous blood was drawn from 35 old hypertension patients when blood pressure was nomial and abnormal, respectively. Epinephrine. norepinephine, endothelins, angiotensin Ⅱ and calcitonin-gene-related peptide were determined by radio-immunity. The above five cytokines were also determined in 33 old healthy people. The cytokines levels were compared between the normal and abnormal blond pressure in hypertension patients and also between the old hypertension patients and healthy persons. The correlation between blood pressure and cytokines were analyzed.

35例老年EH患者,血压正常时和血压波动时各抽取静脉血一次,放射免疫法检测肾上腺素、去甲肾上腺素、内皮素、血管紧张素Ⅱ和降钙素基因相关肽水平,同时检测33例健康老年人群各因子水平,比较EH患者血压波动前后各因子水平的差异和血压正常范围时两组人群各因子水平差异,分析不同状态下血压和各因子水平之间的相关性。

There was no difference between the two groups withregard to plasmatic levels of norepinephrine, epinephrine, cortisol,or ACTH at any sample time, although the blood level of thesehormones significantly increased in each group with surgicalstimulation.

血中肾上腺素,去甲肾上腺素,皮质醇和促肾上腺皮质激素的值虽然由於手术刺激而增高,但是两组间没有差异。

Objective To discuss the methods and effects of the treatment under endoscope and the courses of massive hemorrhage of upper digestive tract after gastrectomy and esophagectomy.Methods Emergency endoscope ex-amination were carried out in20massive hemorrhage clients after gastrectomy and esophagectomy,after exposed and washed the bleeding part by cold0.9%NS,1∶10000adrenaline and hypertonic saline were injected in perifocal sub-mucosa.After stop bleeding and before move back the endoscope,spray some YunNanBaiYao and thrombase in the bleeding part to prevent secondary hemoorahge.

目的 探讨食管、胃切除术后上消化道出血的原因及内镜下治疗的方法、效果方法对食管、胃切除术后引起大出血的患者行急症内镜检查,用冰冻生理盐水100ml+去甲肾上腺素8mg反复冲洗,暴露出血部位后在病灶周围黏膜下注射1∶10000肾上腺素及高渗盐水,无出血后,退镜于出血部位喷洒云南白药及凝血酶,防止再次出血。

Methods Emergency endoscope ex-amination were carried out in20massive hemorrhage clients after gastrectomy and esophagectomy,after exposed and washed the bleeding part by cold0.9%NS,1∶10000adrenaline and hypertonic saline were injected in perifocal sub-mucosa.After stop bleeding and before move back the endoscope,spray some YunNanBaiYao and thrombase in the bleeding part to prevent secondary hemoorahge.

对食管、胃切除术后引起大出血的患者行急症内镜检查,用冰冻生理盐水100ml+去甲肾上腺素8mg反复冲洗,暴露出血部位后在病灶周围黏膜下注射1∶10000肾上腺素及高渗盐水,无出血后,退镜前于出血部位喷洒云南白药及凝血酶,防止再次出血。

Methods Emergency endoscope examination were carried out in 20 massive hemorrhage clients after gastrectomy and esophagectomy, after exposed and washed the bleeding part by cold 0.9% NS, 1:10000 adrenaline and hypertonic saline were injected in perifocal sub mucosa. After stop bleeding and before move back the endoscope, spray some YunNanBaiYao and thrombase in the bleeding part to prevent secondary hemoorahge.

对食管、胃切除术后引起大出血的患者行急症内镜检查,用冰冻生理盐水lOOml+去甲肾上腺素8mg反复冲洗,暴露出血部位后在病灶周围黏膜下注射1:10000肾上腺素及高渗盐水,无出血后,退镜前于出血部位喷洒云南白药及凝血酶,防止再次出血。

Results:The rats occurred rotational behavior to ipsilateral side of intranigral FeCl3 injection; the DA level of FeCl3 and FeCl2 injection side reduced significantly (P<0.01), the A, NA and 5-HT were uneffected.

结果: 注射FeCl3的大鼠出现向损毁同侧的旋转行为;注射FeCl3和FeCl2侧黑质内多巴胺水平显著降低,去甲肾上腺素、肾上腺素和5-羟色胺水平不受影响。

The hemodynamic changes after peritoneal insufflation of CO2 were measured with Swan-Ganz catheterization,and the plasma concentration of epinepherine and nonepinepherine were measured before and after CO2 being insufflated into peritoneal cavity with high performance liquid chromatography-electrochemical method.

20例行腹腔镜胆囊切除患者,随机分成全麻组(A组,11例)和硬膜外+全麻组(B组,9例),采用Swan-Ganz导管技术,监测气腹时血液动力学变化,用高效液相色谱——电化学检测气腹前后血浆肾上腺素和去甲肾上腺素浓度。

HR、MAP、ECG、SPO_2、PETCO_2 and Ppeak were monitored and the venous blood samples were obtained to measure serum concentrations of epinephrine, NE, IL-6 and IL-10 by ELISA at different perioperation time: 5 min before anesthesia (T_0), before the CO_2 was insufflated into peritoneal cavity (T_1)and 5 minutes after(T_2),20 minutes after(T_3), the end of peritoneal insufflation (T4)and 30 minutes after the end of peritoneal insufflation(T_5). Blood samples from artery were obtained atT_1、T_2、T_3、T_4、T_5 for blood gas analysis.

于麻醉前5min(T_0)、气腹前5min(T_1)、气腹开始后5min(T_2)、气腹开始后20min(T_3)、气腹结束时(T_4)及气腹结束后30min(T_5),抽静脉血标本,分离血浆,用ELISA法测肾上腺素、去甲肾上腺素、细胞因子IL-6、IL-10浓度,并于T_1、T_2、T_3、T_4、T_5各时点抽动脉血行血气分析。

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