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Objective To investigate the effects of demethylbellidifolin on activation of hepatic stellate cells and its underlying mechanism.

目的 研究去甲基雏菊叶龙胆酮对肝星状细胞活化的影响及其机制。

"Anti-platelet drugs are often used to reduce intima thickening, for example, restenosis...after angioplasty. Perhaps a different method of inhibiting platelet activation would be to drink dealcoholized beer," Dr. Bassus says."Conversely, the acute consumption of alcohol beverages causes an increase of thrombin generation, suggesting a thrombotic risk in case of acute alcoholic intoxication."

抗血小板药物一般被用来降低血管内膜的肥厚症状,如该药物可预防血管修复手术后的血管狭窄现象,Bassus表示,也许抑制血小板活化的另一种方法就是投予去醇啤酒,然而,过度的酗酒反而会造成凝血酵素的增生,也就是说,急性酒精中毒通常会有缺血的风险。

However, at the beginning of PVR process, stimulated and activated by the initiative factors, RPE begin to dislocate from Bruchs membrane , migrate, proliferate, dedifferentiate, transdifferentiate and secrete provisinal extracellular matrix proteins, followed by membrane formation and contraction on both surfaces of the neuroretina and in the vitreous body, resulted in tractional retinal detachment.

PVR发生后,RPE受到始动因素的刺激,开始活化,脱离原位,去分化,移行、增生、发生表型转化等,并分泌细胞外基质(extracellular matrix, ECM),最终在视网膜前后表面和玻璃体内形成具有收缩能力的增生膜,造成牵拉性视网膜脱离。

Furthermore,activation of nicotinic receptors facilitates the release ofnorepinephrine in the spinal cord.

而且,胆碱能受体的活化有助于脊索的去甲肾上腺素的释放。

CD45, a prototypic receptor-like protein tyrosine phosphatase plays a critical role in the control point for T cell life and death.

CD45是ㄧ个典型的受体型酪胺酸去磷酸酶,主要扮演调节免疫T细胞活化与死亡的角色。

This paper deals with the application of thermoluminescent dosimeters in measuring the doses to patient's gonad and eyes by C.

电脑断层摄影扫描是目前愈来愈普徧的放射线诊断方法,本文系探讨应用自制高敏度镝活化硫酸钙热发光剂量计,在检查过程中实际去测量病人眼都及性腺等器官所接受之辐射剂量。

One practical package of technological formula and parameter about electroplating tinting for ABS plastic are provided, including stress riddance, unoil, coarsing, sensitization, activating, revive treatment, and five-colored electroplating tinting .

介绍(丙烯腈/丁二烯/苯乙烯)共聚物制品的表面预处理、化学镀铜、电镀光亮铜和镀铜层着色等工艺,提供了一整套ABS 电镀着色的实用配方和工艺参数,包括去应力、除油、粗化、敏化、活化、还原处理及镀铜层五色系实用着色等。

Enucleated rabbit oocytes would be used as recipients were activated by electric stimulus before nuclear transfer.

兔去核卵母细胞先经单个电脉冲进行活化刺激,然后进行核移植。

AR signalling can be activated in HR tumours through several mechanisms. First, activation of intracellular signal transduction pathways can sensitize the AR to castrate levels of androgens. Also, mutations in the AR can change AR ligand specificity, thereby allowing it to be activated by non-steroids or anti-androgens. Finally, overexpression of the wild-type AR sensitizes itself to low concentrations of androgens.

HRPC的AR信号通路活化机制包括:胞内信号传导途径可以增加 AR对于去势治疗后低水平雄激素的敏感性;AR的突变也可改变其对于配体的选择,使得非甾体类激素甚至抗雄激素药物也能够激活AR;此外,野生型AR的过表达也促进了自身对于低浓度雄激素的敏感性。

We demonstrated that decapsulated KP, but not capsule polysaccharide fraction or heat-killed KP, triggered up-regulation of BiP/Grp78 and Calreticulin, Caspase12 activation, and enhancements of HLA-B27 homodimers formation and protein degradation in a dose- and time-dependent manner.

实验结果显示并非荚膜或是热杀死之KP,而是去荚膜化后的KP对於细胞株随给予剂量及时间可以引起BiP/Grp78和Calreticulin的高度表现以及活化Caspase12,并促使HLA-B27 homodimers的形成且同时伴随有B27重链蛋白质降解的情形产生。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力