去势

Objective To analyze the effect of castration on risk factors for arteriosclerosis of patients with prostate cancer.

目的探讨前列腺癌患者接受手术去势治疗后由于雄激素水平降低对动脉粥样硬化危险因素的影响。

Methods: A rat model of endometriosis was established by autotransplant of endometria. Forty-eight endometriosis rats were randomly divided into 6 groups: untreated group, castrate group, mifepristone group (5 mg/kg) and low-(20 g/kg), medium-(40 g/kg) and high-dose (80 g/kg) CSG group.

采用自体移植法建立子宫内膜异位症大鼠模型，48只SD大鼠随机分为模型组、去势组、米非司酮(5mg/kg)组和低(20g/kg)、中(40g/kg)、高(80g/kg)剂量红藤颗粒剂组。

Hormone refractory prostate cancer is the progression of disease in the presence of castrate serum levels of testosterone with a median survival of approximately 1 year.

激素难治性前列腺癌是在中位存活时间约为1年的时间里出现睾酮的去势血清水平的疾病的进展。

At first, a castrated rat model was used to study the microcirculation of prostate post castration.

本研究首先采用去势大鼠动物模型，力图全面地观察大鼠去势后前列腺微循环的变化特点。

These results suggested that estradiol or testosterone had no effect on I〓 in castrated male rats; but in chronic eastadiol or testosterone treated females the I〓 density was higher in epicardium than in endocardium, and eastadiol group produced I〓 transmural dispersion.

雌二醇或睾酮对雄鼠去势后各组的I〓不产生影响；但慢性使用雌二醇或睾酮后使去势雌鼠心外膜的I〓密度比心内膜更高，且雌二醇组产生I〓跨室壁离散。

After treatment with the above hormones, the rats were established anesthesia with urethan (1g/kg, i. p.); polyethylene catheters were inserted into the external jugular vein and the common carotid artery for drug administration, and then blood pressure was recorded. The arterial catheter was connected to a pressure transducer, and the blood pressure was displayed on the channel of BL-310 Experimental System of Biological Function through IBM computer. We assessed the changes of resting arterial blood pressure, the pressor responses of angiotensin Ⅱ(Ang Ⅱ, 0.01mg/kg), noradrenaline (NA, 0.01mg/kg) and adrenaline (Adr, 0.016mg/kg). The depressor responses of Ach (0.006mg/kg) and carotid sinus baroreflex were also discussed after treatment with the hormones in OVX rats.

用不同雌激素处理21天后，将动物用25％的氨基甲酸乙酯腹腔麻醉（1g／kg），做颈总动脉插管，通过压力换能器，将血压变化输入计算机，通过BL-310智能型生物信号显示与处理系统的压力测定模块，观察去势鼠及不同雌激素替代治疗大鼠静脉注射血管紧张素Ⅱ（AngⅡ，0.01mg／kg）、去甲肾上腺素（NA，0.01mg／kg）、肾上腺素（Adr，0.016mg／kg）的升压反应以及乙酰胆碱（Ach，0.006mg／kg）的降压反应和压力感受性反射的变化。

ERα is the major subtype of estrogen receptor in vaginal tissue of rats. ERα and ERβ expressions are down-regulated in the vaginal tissues after ovariectomy. Our findings show that estradiol valerate can up-regulate the expression of ERα but ERβ.

ERα是大鼠阴道优势表达的雌激素受体亚型；去势后阴道ER亚型表达下调，以ERβ明显；戊酸雌二醇可明显上调去势大鼠阴道ERα的表达，但不上调ERβ的表达。

Considering the merits of in vivo studies in biotransformation i. e. activation or inactivation, protein-binding such as sex hormone binding protein , toxicokinetics, and more evaluative in hazard identification and risk assessment, we selected a battery of short-term and long-term in vivo studies, including uterotrophic assay in weaning mice and ovariectomized adult mice, an in vivo multiple endpoints assay, and a gestational and lactational exposure assay to identify the estrogenic effects of endosulfan on the offspring.

考虑到体内试验在代谢转化、血浆蛋白如性激素结合蛋白的结合、代谢动力学等方面比体外试验优越，在危害鉴定和危险度评定中更有价值，我们选择了多项体内试验，包括对幼年小鼠和卵巢切除成年小鼠的子宫增殖作用、对成年去势小鼠的体内多终点观察以及大鼠孕期和哺乳期接触对雄性子代生殖系统结构和功能的改变，即去雄性化或雌性化作用等，来验证硫丹的体内雌激素样作用。

The sham operation group only underwent the excision of fat tissues on back, and then sutured.

将去势对照组和去势加载组大鼠双侧背部卵巢切除，假手术组背部切口除去少量脂肪后，闭合伤口。

Sixteen Landrace×Yanan barrows(55 kgBW),16 Landrace×Yanan gilts(55 kgBW) and 32 Landrace×Yorkshire barrows(65 kgBW) were allocated to treatment (4 mg pST/pig·d)or control group (0 mg pSTs/pig.d) for 28 days to determine effects of exogenous somatotropin on somatotropin level in tissues.

选用长雅去势公猪和母猪各 16头，长约去势公猪 32头，按 2× 2× 2因子设计，每头每天分别注射生长激素 4mg或 0mg ，持续 2 8d ，测定外源生长激素对组织中生长激素水平的影响。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。