原纤维间的

This study investigated the mechanisms that induce EMT and the significance of extracellular signal-regulated kinase cascade in this course in vitro.

本文旨在研究酸性成纤维细胞因子对上皮-间质转分化的影响，探讨有丝分裂原激动蛋白激酶的ERK信号传导途径在此过程中的作用，为肾小管-间质纤维化的防治提供理论依据。

The corium is under the epidermis, it's made up of connective tissue that contains collagenous fiber, elastic fiber, reticular fiber and ground substance between fasciculus, it's very important for the elasticity and lusty of the skin, malnutrition, ageing and long-time excessive exposure to the sun would all lead to wrinkles and sagging of the skin, the reason of this is denature or fracture of collagenous fiber and elastic fiber.

真皮在表皮之下，由胶原纤维、弹力纤维和网状纤维组成的结缔组织，与纤维束间的无定形基质构成，对皮肤的弹性光泽和弹力等有着重要作用，营养不良、衰老或长期过度日晒会使皮肤发生皱纹、弹性松弛，是胶原纤维及弹力纤维变性或断裂的结果。

Atrophy of myocardium, expansion of mitochondria,destruction of myofibril and interstitial fibrosis are the main morphological changes of diabetic cardiomyopathy, and lipid peroxidation and NO may be involved in it.

糖尿病大鼠心肌病变主要为心肌萎缩、线粒体扩张及肌原纤维破坏，间质纤维增生，脂质过氧化作用及NO所致的损伤可能参与其中。

2Cm bone defect was established in ulna of rabbits, the capacity of different therapeutic measures in bone defect repairment was determined in groups A , B (implanted BMP, TGF -β〓 and carrier) and C . It was found that the appearance of osteoblasts and formation of bone union were earlier and the number of osteoblasts more in group B than in group A. The amino acid analysis revealed that the volume of ossein was significantly higher in group B than in group A at the early stage.

分别用bBMP及载体bBMP、TGF-〓及载体和单纯载体修复兔尺骨1.2cm骨缺损的实验模型来比较三者间的成骨效果，结果表明B组比A组成骨细胞出现早、形成数量多、骨连接形成提前，骨胶原氨基酸分析在骨缺损修复早期胶原形成量B组均高于A组，且B组以形成Ⅰ型胶原为主，C组表现为一纤维形成过程。

The microstructure of the scaffold was observed under photomicroscope and scanning electron microscopy,and the in vitro degradation time,permeability,tensile-strength,porosity,shrinka...

实验结果显示：支架中的成纤维细胞、脂肪细胞及组织纤维间质完全去除，胶原纤维得到了松散，并维持其原有的天然三维网络多孔结构；该材料透水汽性处于3000g.m-2.d-1左右，适合创面恢复；体外降解时间处于25～50h之间，并可根据需要调整工艺条件控制降解时间；拉伸强度介于10.20～11.50MPa之间，具有良好的拉伸强度；收缩温度介于70～85℃之间。上述结果表明该材料已解决了猪脱细胞真皮基质渗透性差、降解速度过慢的缺点，并且其透气性和拉伸强度高、降解性优良且可控，符合组织工程支架材料的要求。

Six weeks after implantation, small amount of oval lacunae appeared. PGA fibers began to be absorbed. The amount of collagen increased and Safranin O stained positively. Eight weeks after implantation, cartilage with single or occasionally double chondrocytes in round lacunae was found.

体内埋植4周后可见PGA纤维间被不成熟的软骨细胞充填。6周时出现椭圆形软骨陷窝，PGA纤维开始吸收，胶原增多，番红花—"O"有阳性染色。8周时软骨陷窝呈圆形，单个，双个对称或多个排列。

Demonstrative green tea can reduce gland purine to be damaged to the qualitative pathology between bandicoot kidney, green tea has fight the action that qualitative fiber changes between kidney, and can restrain hyperplasia of fibrous of I,Ⅲ collagen, this may be green tea qualitative fiber is changed between kidney of prevention and cure, one of mechanisms that defer chronic kidney failure to develop a process.

说明绿茶能够减轻腺嘌呤对大鼠肾间质的病理损害，绿茶有抗肾间质纤维化的功能，并且能抑制I、Ⅲ型胶原纤维的增生，这可能是绿茶防治肾间质纤维化、延缓慢性肾衰竭发展进程的机制之一。

The alveolitis that produces fibroblast proliferation and collagen deposition is progressive over time.

肺间质发生成纤维细胞的增生，成纤维细胞可以分泌大量的胶原纤维，最终导致了肺间质纤维化。

Purpose To study the role of pulmonary macrophages in the collagen deposition of fibrotic interstital lung disease.

目的：探讨肺泡巨噬细胞在纤维性间质性肺病胶原纤维异常沉积中的作用。

RESULTS The degenerative changes of nerve ending in Meissner's corpuscles were observed after 1 month of denervation, and the basic structure of the corpuscles had no obvious changes. After 3 months, the axons of corpuscles were disappeared, and the volume of corpuscles was shrunk. The basic structure of nerves was disappeared, and the lemmocyte and neurolemma plate were changed after 5 months.

结果 失神经1个月时触觉小体内的神经末梢已有溃变，触觉小体的基本结构无明显改变；3个月时轴突消失，触觉小体的体积开始萎缩；5个月时神经结构消失，膜细胞及其膜板亦开始改变；8个月时触觉小体内胶原纤维含量逐渐增多；12个月时触觉小体内膜结构与膜间基质完全消失，被胶原纤维代替。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。