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Rat in Group B was set an air bladder which was empty and not perfused water. Water of 0.6 ml, 0.8 ml, 1.0 ml, 1.2 ml, 1.4 ml and 1.5 ml was perfused respectively into the air bladders which were set in the colon of rats in group C, D, E, F, G and H. Then the changes of ethology of the rats were recorded in interval of an hour.

应用疼痛行为学的观察方法,观察1h各组动物的行为学改变,并采用免疫荧光化学的方法,观察大鼠DCN中神经元被激活的标志c-fos及胶质细胞的胶质原纤维酸性蛋白(glial fibrillary acidic protein, GFAP)和小胶质细胞特异性补体OX42的表达情况,空白对照组是在疼痛高峰点(1.2 ml)处死取材。

Research of ultramicro- structure of anal sphincter in the cases of patients with fecal incontinence shows : shortness of smooth muscle cells of anal sphincter , destruction of normal structure of the rest cells , elongation of elastic tissue and increase of collagen fibers. Thus the most familiar cause of copracrasia is Degeneration of finespun smooth muscle of anal sphincter which mantain anal sphincter closed .One of the pathomechanism of fecal incontinence is decrease of anal resting pressure .

对大便失禁者肛门内括约肌的超微结构研究发现:肛门内括约肌的平滑肌细胞缺失、剩余细胞的正常关系破坏、弹性组织拉伸、胶原纤维成分增加,因而大便溢漏最常见的原因是维持括约肌关闭的肌肉-肛门内括约肌的纤细平滑肌的退行性病变,肛管静息压降低是大便失禁发病的一个病理学机制。

The essence granule of caviar extracted from paddlefish contains abundant protein and AA+ which is biological growth hormone for the major components of skin collagen and elastane fibre.

从这些大白鲟鱼里提取的鱼仔精华颗粒蕴含了丰富的蛋白质和AA+是皮肤胶原蛋白及弹力纤维的主要成分生物生长激素:能够活化细胞,延缓衰老的功效,并把深海最神秘的因子带给广大的消费者,让肌肤重返青春容颜。

The molecular mechanism in hypertensive kidney lesion was demonstrated by monitoring the levels of serum TGF-β, nitric oxide and plasma AngH in essential hypertensive patients and investigating the effect of information convection in endothelial cell on fibrillar collagen metabolism and its relationship with hypertensive kidney lesion.

该课题通过测定原发性高血压病人及伴肾脏损害病人的TGF-β_1、NO和Ang Ⅱ的水平,探讨内皮细胞产生的信息传递对纤维胶原代谢的影响及与高血压性肾损害的关系,以揭示高血压性肾损害发生发展的细胞分子机制。

A special delaminated expression was observed in the pericystic layer of hepatic hydatid cyst Collagen Ⅰ,Ⅲ and Ⅳ expression in the side of pericystic layer directed to the cyst of parasite(50 0%,37 5% and 40 0%) were lower than those in the side of pericyst...

靠近虫体侧纤维囊壁中,Ⅰ、Ⅲ和Ⅳ型胶原的表达阳性率分别为500%、375%和400%。靠近肝实质侧纤维囊壁中,Ⅰ、Ⅲ和Ⅳ型胶原的表达阳性率分别为875%、825%和850%。Ⅰ、Ⅲ、Ⅳ型胶原在两层中表达的差异均有显著意义(P01,P01,P01)。肝包虫囊肿周围人体纤维囊壁分层,Ⅰ、Ⅲ和Ⅳ型胶原与肝实质侧纤维囊壁的形成有密切关系。

Objective: To explore the mechanisms resulting in the recurrence of urethral scar which make urethral strictures difficult to be cured, a series experiments were conducted to find potential effective factors involved in urethral scar formation and degradation, including the studies of extracellular matrix component of urethral stricture scar, the characteristics of urethral scar fibroblast, and the effects of urine on urethral fibroblast in vitro, as well as the studies to compare the difference of collagenase activity, type Ⅰ collagen and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the tissues and cultured fibroblasts from normal urethra and strictured urethra respectively, and the studies to investigate the effect of antisense TIMP-1 oligodeoxyonucleotide on cell proliferation and collagenase activity of urethral scar fibroblast.

中文题名尿道瘢痕基础研究副题名胶原酶活性,TIMP-1的表达及其反义基因治疗外文题名 Experimental study on urethral scar-activity of collagenase,expression of TIMP-1,and antisense TIMP-1 gene transfection of urethral scar fibroblast 论文作者黄翔导师杨宇如教授学科专业外科学研究领域\研究方向学位级别博士学位授予单位四川大学学位授予日期2002 论文页码总数104页关键词尿道手术瘢痕胶原酶成纤维细胞尿道瘢痕馆藏号BSLW /2003 /R699 /12 目的:研究尿道瘢痕的细胞外基质的组成,尿道瘢痕成纤维细胞的生物学特性以及尿液对其生长的影响;比较胶原酶活性,金属蛋白酶组织抑制因子-1(TIMP-1)以及Ⅰ型胶原含量在尿道瘢痕和正常尿道组织及体外培养的成纤维细胞中的差异;研究反义TIMP-1寡核苷酸对尿道瘢痕成纤维细胞增殖以及胶原酶活性的影响。

Plant cellulose A extract, through the metabolic stimulation on the epidermis and dermis of eye lines, makes keratinized cell differentiation, promotes epidermal renewal, and promote the repairing of eye wrinkles by stimulating the synthesis of collagen and weakening the activity of metalloprotease that destructs elastic fiber.

植物纤维素A提取物,通过对眼纹的表皮和真皮层的代谢性刺激作用,对角质细胞分化,促进表皮更新,通过刺激胶原蛋白的合成和削弱造成弹性纤维毁坏的金属蛋白酶的活性,促进眼部皱纹的修复。

Some cell dropped into the cavity and became free. Thrombosis or part organization could be seen. The internal elastic layer became thin, disappear or broken. In internal and middle layer existed fibroblasts, fibrocytes and collagen. Some of the wall indicated hyaline change, soomth muscle cell decreased greatly. The massive inflammatory cells invaded the middle and external layer. There were many foam cells in the capsule tissue. Cytoplasm was filled with fatty tissue and cholesterol. some cavities were full of thrombosis. Some thrombosis was fibrosis, the bottom was organization. The surface of the thrombosis existed red blood cell and librae.(2)Elatic fibrila staining: the internal elastic menbrane almost completely disappeared, the intact internal elastic menbran could be seen in the new small vessels.

动脉瘤管壁厚薄明显不均,全层或局部区域显著变薄向外膨出,内皮细胞空泡变性或坏死脱落,部分内皮细胞剥离并突入管腔成游离状,可见血栓形成及部分血栓机化;内弹力板变薄、消失或突然中断;在内膜及中膜部位主要为纤维母细胞、纤维细胞和大片胶原;部分动脉瘤壁呈均质状玻璃样变,平滑肌细胞明显减少;中膜和外膜可见大量的炎性细胞浸润;瘤壁组织有纤维母细胞、纤维细胞、大片胶原成分及较多泡沫细胞,胞浆内充满脂类物质及胆固醇结晶;部分动脉瘤腔内充满血栓,有的血拴已经纤维化,血栓基部机化,血栓表面有红细胞和纤维素。

Cell sheet transplantation regenerated both new bone and cementum connecting with well-oriented collagen fibers, while only limited bone regeneration was observed in control group where cell sheet transplantationwas eliminated.

结果发现,细胞膜片移植再生出了新骨、牙骨质以及连接二者的排列整齐的胶原纤维,而在没有进行细胞膜片移植的对照组只观察到了有限的骨再生。

In contrast to rat-tail collagen-based HSEs, the present fibroblast-derived matrix-based HSEs contain more continuity in the number of viable cell layers in long-term cultures.

同鼠尾胶原来源的皮肤替代物相比较,在长期的培养过程中人成纤维来源的的模型包含更多的数量的细胞层。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

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