原粒细胞

RESULTS: Microscopically, the lesion consisted of abundant collagen fibrils, proliferated histiocytes and numerous infiltrated plasmocytes, lymphocytes and eosinophilic granulocytes. Fusiform or polygonal histiocytes had abundant, granular, eosinophilic cytoplasm or clear cytoplasm containing radially oriented strands or resembled xanthoma cells. Emperipolesis of numerous small lymphocytes was seen in the cytoplasm of some large histiocytes.

结果： 镜下可见丰富的胶原纤维和组织细胞增生以及大量浆细胞、淋巴细胞和嗜酸粒细胞浸润，组织细胞呈梭形、多边形，胞质嗜酸性颗粒状、放射条纹状或泡沫状，一些大组织细胞质内有多量小淋巴细胞。

RESULTS摘要: Microscopically, the lesion consisted of abundant collagen fibrils, proliferated histiocytes and numerous infiltrated plasmocytes, lymphocytes and eosinophilic granulocytes. Fusiform or polygonal histiocytes had abundant, granular, eosinophilic cytoplasm or clear cytoplasm containing radially oriented strands or resembled xanthoma cells. Emperipolesis of numerous small lymphocytes was seen in the cytoplasm of some large histiocytes.

结果摘要：镜下可见丰富的胶原纤维和组织细胞增生以及大量浆细胞、淋巴细胞和嗜酸粒细胞浸润，组织细胞呈梭形、多边形，胞质嗜酸性颗粒状、放射条纹状或泡沫状，一些大组织细胞质内有多量小淋巴细胞。

Granulocytic sarcoma (also preiously known as Chloroma) refers to tumor-like lesions of extramedullary myeloid leukemia.

缩略图，点击图片链接看原图）粒细胞性肉瘤以往也称作绿色肉瘤，肿瘤病变类似于髓外的髓样白血病。

Subacut myeloid leukemia can be a defined type of leukemia. The common characteristics of subacute myeloid leukemia are as follows: the onset is insidious, and anemia and hemorrhage of skin and mucosa are the main clinical manifestations. Hepatosplenomegaly is rare. There are multilineage abnormalities in blood cell counts and increased blasts in the bone marrow with cytogenetical abnormal clone in most cases. The disease course is subacute and progressive.

1、亚急性髓性白血病是一个可以确定的白血病类型，其特征为：起病隐袭，以贫血或皮肤粘膜出血为主要症状，肝脾肿大的特征较少，血象为一系、二系或三系的异常，骨髓细胞形态学检查原早幼粒细胞异常增高，细胞遗传学检查多数有克隆性异常核型，病程中可有克隆演进，呈现亚急性而进行性的临床经过。

CML is cytogenetically marked by the philadelphia chromosome, which originates from a reciprocal translocation between chromosome 9 and 22 and is molecularly marked a chimeric bcr-abl gene, resulting from juxta-positive of the abl proto-oncogene on chromosome 9 with the bcr gene, which is normally located on chromosome 22. The chimeric bcr-abl gene expression an 8. 5kb hybrid mRNA transcript giving rise to a 210-KD fusion protein (P210〓) with increased tyrosine kinase activity. P210〓 plays a key role in the pathogenesis of CML. The continuous cell line K562 was established from the pleural effusion of a 53-year-old female with CML in terminal blast crisis, and was a human erythroleukemia line, contained Ph chromosome.

绝大多数慢粒患者白血病细胞中具有Ph染色体，是由9号染色体长臂3区4带和22号染色体长臂1区1带相互易位形成，即t（9；22），使位于9q〓的c-abl原癌基因在第二外显子的5'端断裂并易位到22 q〓的M-bcr基因第2或第3外显子的3'端，形成异常的bcr-abl嵌合基因，该基因转导出异常的mRNA，编码并翻译出P210蛋白，该蛋白具有很强的酪氨酸激酶活性，使粒细胞发生恶性增殖。K562细胞属于慢粒急变、红白血病细胞株，具有Ph染色体。

Cytologically, there were rare neutrophils and macrophages at the margins of the specimen, which was consistent with a mild inflammatory reaction to the extruded allograft-collagen sponge complex.

细胞学方面，标本的边缘见少量中性粒细胞和巨噬细胞。与所取骨－胶原海绵复合物有中度炎性反应相一致。组织培养未见感染。

METHODS: We searched for abnormalities of the proapoptotic Bcl-x deamidation pathway in primary cells from patients with chronic myeloid leukemia or polycythemia vera, myeloproliferative disorders associated with the BCR-ABL fusion kinase and the Janus tyrosine kinase 2 (JAK2) V617F mutation, respectively.

我们分别对来自慢性粒细胞白血病或真性红细胞增多症、骨髓增生性疾病相关的BCR-ABL融合蛋白激酶及Janus酪氨酸激酶2 (JAK2) V617F突变体患者原代细胞凋亡前Bcl-x脱酰胺途径的异常情况进行研究。

While diagnosing and treating SARS cases, doctors should rule out the possibility of other lung diseases with similar clinical manifestations, such as primary bacterial or fungal pneumonia, pulmonary tuberculosis, lung tumor, non-infective interstitial lung diseases, pneumonedema, atelectasis, pulmonary embolism, pulmonary infiltration with eosinophilia, and pulmonary agents.

答：在非典型肺炎的诊断治疗过程中，首先要注意排除原发细菌性或真菌性肺炎、肺结核、肺部肿瘤、非感染性肺间质性疾病、肺水肿、肺不张、肺栓塞、肺嗜酸性粒细胞浸润症、肺血管炎等临床表现类似的肺部疾患。

P＜0.01. 28d, q=4. 0452, p＜0.05 . Corresponding pathologic result shows that the corneal stromal of height edema increase thickness to have infiltration of inflammation cells with hyperplasia of fibroblast cell and large vessel. The collagen fiber in stromatic layer is dissolved and destroyed seriously, suggesting that in addition to HSV-1's direct destructuring effect, inflammatory cells that might play an important role in the pathology of HSK induce the immune-pathological reaction.

相应的组织病理学研究结果显示（UV-B 14天）：病毒对照组角膜基质层高度水肿、增厚，并有大量中性粒细胞等炎性细胞浸润、成纤维细胞和新生血管增生，胶原纤维肿胀、分解等，说明除HSV-1对角膜组织直接破坏外，炎性细胞介导的免疫病理反应在复发性HSK发病机理是重要的因素。

Moreoer, as documented in the report by Walsh et al., breakthrough fungal infections, especially with molds such as aspergillus and zygomycetes, also occur.

临床医生在治疗免疫功能低下的中性粒细胞减少症患者（正在接受经验性抗细菌和抗真菌治疗）时，必须对一些潜在可能的感染原保持高度的警惕。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。