原尾蚴

Objective To detect antigenicity of collagen of cysticarcus cellulosae.

目的检测猪囊尾蚴胶原蛋白的抗原性。

The people perhaps are infected by swallowing the infected Cyclops or by procercoid attack through skin or mucous membrane.

感染的方式和途径可能是误食受感染的剑水蚤，或者是原尾蚴直接经皮肤和粘膜侵入。

Objective To explore antigens possessing common immunogenicity with Schistosoma japonicum cercariae antigens, and to find out new candidate antigens for schistosomiasis diagnosis and vaccine.

目的 筛选与日本血吸虫尾蚴抗原有共同免疫原性的日本血吸虫成虫抗原分子，为血吸虫病诊断和疫苗研究提供新的候选分子。

Methods Hepatic fibrosis models of rabbits were made by appling abdomen walls with the cercarias of Schistosome japonica.The rabbits were randomly categorized into four groups:normal control,4,8,12 weeks after application.The level of transforming growth factor-beta1(TGF-β1) mRNA in hepatic tissues was examined by reverse transcription polymerase chain reaction. The level of expressions of Smad3 was examined by Western blot. Meanwhile,immunohistochemistry staining was assessed by measuring type Ⅰ collagen .

日本血吸虫尾蚴腹贴法制备家兔肝纤维化模型(n =32 )，按诱导时间将动物随机分为 4、8、12周及正常对照共 4组，采用逆转录多聚酶链反应检测肝组织中转化生长因子TGF -β1mRNA表达水平，免疫组织化学法检测Ⅰ型胶原的表达，同时应用Westernblot检测Smad3蛋白的表达。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。