原因明显的

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Compared with 810S,the total photosynthetic pigment content of Biao 810S was aabout 50%lower;which was the main cause of the yellow green leaf.2、The spikelet numbers,stigma exsertion rate and flowering time of Biao 810S were same as that of 810S.There were no significant difference of the agronomic traits between the the cross combination which came from the maintainers D100 and R96-1 and the combination from 810S.3、The photosynthetic rate of Biao810S was higher than 810S under strong light and lower under weak light.

叶绿素含量下降是标810S叶片呈淡黄绿叶色的根本原因。2、标810S的颖花数、柱头外露率和开花时间与对照基本相当，与恢复系D100和R96-1配制的杂交组合农艺性状与用810S配制的相应推广组合无明显差异，表明标810S可替代810S应用于两系杂交水稻，其淡黄绿叶色性状可应用于杂交制种田的不育系群体除杂，同时可根据幼苗期淡黄绿叶色性状植株的比例用于鉴定杂交组合中不育系的混杂率。3、弱光条件下标810S的光合速率低于810S，强光条件下标810S光合速率比对照高，且标810S在光强2400μmol·m~(-2)·s~(-1)以下没有光饱和点和"午休"现象。

The mechanism of the impact of satellite-city on urbanization is industrialization and the third industry development and so on. Finally, with careful analysis on the problem in the development of satellite-cities, The article expound the question existing of satellite city : the disparity in urban and rural areas is great, the great difference between satellite-city and central district, the problem of the peasantry who lost glebe and so on. The article defined the function of each satellite-city and put forward policy advice.

本文也分析了卫星城市推动城市化的原因：工业化、第三产业的迅速发展，产业结构的调整等；最后分析了成都卫星城在发展中存在的问题以及发展的制约因素，如：卫星城的二元性特征明显、卫星城与中心城市相差悬殊、失地农民问题等，最后根据各个卫星城的比较优势作出了功能定位，从整体上提出了发展的建议。

Ultimatums, bringing up past pain andunresolved issues, jealousy, or unusual neediness or possessivenessmay all be part of the scenario, and what makes all of this quitestressful is that most of it is not blatant but subtle andinsidious.

最后通牒：提起过去的伤痛与未解决的问题，嫉妒，不同寻常的穷困与占有欲都有可能成为这次的剧情。这些因素会造成关系紧张的原因是他们并不明显反而微妙且阴险。

Analyses the features and the problems of the explosion door of the air shaft and improves the structural steel ring and the balance weight of door.

分析了煤矿风井防爆门存在的漏风、密封液选择、使用比较困难和开闭不便等问题及其原因，并针对这些问题对防爆门的型钢圈和平衡重锤进行了改进设计，实践证明，改造后的新型防爆门性能明显优于改造前，提高了煤矿风井防爆门的安全可靠性，具有一定的推广价值。

Specific protein bands were observed in cellular and extracellular protein electrophoresis for both strains 593 and 18.There were also different protein expression in certain protein bands.It is indicated that a significant difference existed between the proteome of strains 593 and 18.This difference may contribute to the different cariogenic potential of these two strains.

两菌株的菌体和菌外可溶性蛋白电泳图谱中均可见各自特异表达的蛋白条带，且部分相同位置的蛋白条带在蛋白表达量上也存在差异，表明两菌株的蛋白组存在明显差异，该差异可能是导致其致龋力差异的原因之一。

A significantly higher risk of deeloping anemia compared with women who were HI negatie. This can lead to lower tolerance to seere bleeding after birth, one of the most common causes of maternal death.

与HI阴性的妇女相比，HI阳性的孕妇发生贫血的机率明显增加，这将会降低孕妇对严重的产后出血的耐受性，而产后出血是造成孕产妇死亡的最常见原因。

The results were as follows: with the shortened distance from the forest edge, photosynthetic rate of rice quadrats were gradually reduced; while the temperature, relative humidity and CO2 concentration in rice population did not change significantly; rice yield declined in a row, mainly because of a significant decreased panicles per unit area.

结果表明，随着与林缘距离减小，样方水稻的光合速率逐渐降低，而水稻群体内的温度、相对湿度和CO2浓度的变化不明显；水稻产量连续下降，其主要原因是单位面积穗数的大幅度降低；而不同林缘距离样方水稻的千粒重和结实率变化甚微。

It was observed as follows:(1)The body temperatureof the cord transectedanimals fell in a good agreement with ambient temperature.It appears thatthe fall in B.T.is one of the main causes inducing ulceration.(2)Administrationof epinephine decreased ulceration and prevented the fall in B.T.both in a dose-dependent manner.(3)Cord transection induced ulcer formation was markedlyattenuated by adrenalectomy and exacerbated aga...

结果表明：(1)脊髓横断动物的体温随环境温度而下降，体温的下降可能是诱发溃疡的重要原因之一；(2)注射肾上腺素可减轻溃疡和防止体温下降，且两者均呈剂-效关系；(3)切除肾上腺可使脊髓横断诱发的溃疡明显减轻，如补充注射地塞米松则可使之重新加重，但体温的下降在以上情况下均不受影响；(4)脊髓横断后胃粘膜泌酸和内分泌功能的改变可能与溃疡生成有关。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了