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The cardiac,renal, digest and nervous system are more likely to be affected in the primary amyloidosis.

结果 原发性者14例,以男性为主,继发性者3例。心、肾、消化及神经系统是常见的受累脏器。

There were 36 males and 40 females,with the average age of 47.7 years.36 patients presented with sciatica and perineal numbness,11 patients had painless mass and the other 20 were identified due to other causes.Among 67 benign neurogenic tumors,54 were originated from S1-S3 nerves,3 from S4-S5 nerves and 11 from the presacral space without caudal involvement.Giant cell tumor was found in 60 patients,which included 24 males and 36 females,with an average age of 32 years.Upper sacrum(S1-S2) was involved firstly.There were 56 patients(average,37.7 years) diagnosed as other primary benign bone tumors,which included 24 cases of teratomas,epidermoid cyst or dermoid cyst.Other malignant tumors,including chondrosarcoma (17),Ewing′s sarcoma/PNET(14),multiple myeloma(12),lymphoma(6) and osteosarcoma(6) were found in 64 patients.

其中脊索瘤95例,男62例,女33例,平均年龄55.7岁,骶尾区疼痛是主要症状(82例),半数以上患者伴有坐骨神经痛,肿瘤多先累及低位骶骨(S3~S5);神经源性肿瘤76例,男36例,女40例,平均年龄47.7岁,神经纤维瘤43例,神经鞘瘤24例,恶性神经鞘瘤9例,主诉多为坐骨神经痛、会阴部麻木(36例)和无痛性包块(11例),20例患者为查体或其他原因检查时发现,67例骶骨良性神经源性肿瘤起源于S3以上神经者54例,起源于S3以下神经者3例,发生于骶前未累及骶管者10例;骨巨细胞瘤60例,男24例,女36例,平均年龄32岁,腰骶尾部不适(37例)、坐骨神经痛(21例)是主要的临床表现,肿瘤多先累及上位骶骨(S1~S2);骶骨其他原发良性肿瘤及瘤样病变56例,包括畸胎瘤、皮样囊肿、表皮样囊肿共24例;其他原发恶性肿瘤64例,包括软骨肉瘤17例,尤文肉瘤14例,多发性骨髓瘤12例,成骨肉瘤6例等。

Result] Under blood stasis, it can to some extent inhibit the production of primary cancer, the serum IL18 and HGF were reduced in mouse of liver metastasis with cancer, which may intervene the liver metastasis; Shensanqi extract had some definite function on the primary cancer of spleen and liver metastasis of rats with liver metastasis of cancer, the platelet exerted key functions in cancer hyperplasia, infiltration and metastasis.

结果]在血瘀状态下,可在一定程度上抑制原发肿瘤的生长,荷瘤肝转移小鼠血清IL18和HGF的水平降低,可能干预了肝转移的过程,参三七醇提液对荷瘤肝转移大鼠的脾脏原发肿瘤的生长和肝转移有一定抑制作用,血小板在肿瘤增殖、浸润和转移中起着重要作用。

Cervical lymphadenopathy at initial presentation occurred in 12 patients.

结果:44例有完整随访资料的患者中,37例原发于鼻腔粘膜,5例原发于副鼻窦粘膜,2例原发于鼻咽粘膜。

RT-3DE shows clearly full view of the primary atrial tumor than two-dimensional echocardiography and obvious image differences between atrial myxoma and malignant atrial tumor. It is a convenient, quick and precise modality for diagnosing primary atrial tumor and may be of significant clinical value for the diagnosis of primary atrial tumor.

RT-3DE比二维超声心动图更清晰显示原发心房肺瘤全貌形态,黏液瘤与恶性心房肿瘤图像特征差别明显,RT-3DE是诊断原发心房肿瘤简便、快捷和准确的检查方法,RT-3DE对原发心房肿瘤具有重要临床诊断价值。

The primary localized amyloidosis of bronchotracheal tree have characteristic radiographic findings, but the primary systemic amyloidosis have no distinctive radiographic findings, the diagnosis relies on pathology.

局限于气管支气管树的原发淀粉样变病具有一定的影像特点,而全身性原发淀粉样变病累及胸部的有关影像学表现缺乏特征性,诊断依靠病理活检。

Metastasis: A process in which that the tumor cells invade into vessels or coeloms and are transferred through blood, lymphatic and coelomic paths to other parts of body where they implant and grow into a secondary tumor.

定义:肿瘤细胞浸润到淋巴管腔、血管腔或体腔随体液运行或经体腔种植被带到它处,停留继续生长形成与原发瘤类型相同的肿瘤。原发瘤,继发瘤

About 48%(90/194) were below 29 years of age. Ninety-nine of 194 cases had either radiotherapy alone or supplementary treatment with radiotherapy following surgery. We analyzed multiple prognostic factors. The factors of importance included postoperative radiotherapy; female in glioblastoma multiforme; the primary tumor dose above 5000 rads and/or whole brain irradiation in malignant astrocytoma and glioblastoma multiforme; the primary tumor dose above 4500 rads in ependymoma, medulloblastoma and oligodendroglioma; and spinal axis irradiation above 2000 rads in ependymoma and medulloblastoma that produced a better prognosis than in other groups.

男与女之比例为2.7比1,年龄分布自1至81岁,平均年龄33.3±19.3岁,中值年龄为34岁,29岁以下占48%(90/194),其中99例单独或手术后辅以放射腺治疗,分析同种脑瘤的预后因素,其中多形神经胶母细胞瘤有手术后放射线治疗或女性,多形神经胶母细胞瘤合并星细胞瘤原发肿瘤剂量5000雷得以上或曾全颅腔照射,神经管胚细胞瘤,间胶质母细胞瘤,及室管膜瘤原发肿瘤剂量4500雷得以上,室管膜瘤及神经管胚细胞瘤有脊轴照射2000雷得以上预后均佳,且统计上有显著的差异。

This appearance is pathognomonic. The optimum treatment is ablation of the bleeding source, however no source is detected in most cases.

中枢神经系统表面含铁血黄素沉积症的最佳治疗为切除颅内出血原发灶,但大部分病人均找不到颅内出血的原发灶。

(1)In NSCLC, the overexpression of Ezrin and the abnormal expression of E-cadherin were correlative with primary carcinoma with metastatic carcinoma. The expressions of Ezrin and E-cadherin in primary NSCLC tissues and in metastatic carcinoma of lymph nodes were different. All of these suggested that the overexpression of Ezrin and the abnormal expression of E-cadherin may promote tumor metastasis. The investigation of Ezrin and E-cadherin may be useful for offering one method to prevent tumor from metastasizing.

(1)在NSCLC中,Ezrin的过度表达与伴有癌转移的原发性NSCLC有关,并且在淋巴结转移灶中的过度表达高于原发灶;E-cadherin的异常表达与伴有癌转移的原发性NSCLC有关,并且在淋巴结转移灶中的异常表达高于原发灶;以上均提示Ezrin过度表达和E-cadherin异常表达可能促进肿瘤转移,对Ezrin与E-cadherin的研究可能有助于提供一种阻止NSCLC患者肿瘤转移的治疗措施。

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