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Results there were unconsciousness, respiratory rhythm disturbance and hyporeflexia of pupil light reflex immediately after injury, and reactiveness decrease and activity retardation still existed even after resuming consciousness. at anatomical scene, subarachnoid hemorrhage or cerebroventricular haemorrhage were widespread. at an early stage, there were swelling, collapse, and axonal retraction ball formation at cortico-medulla junction, callosum, brainstem, and cerebellar white matter under microscope. but at the later stage, gitter cell proliferation and nest-like aggregation were major pathophysiological changes at focal brain tissue.

结果 伤后大鼠均即刻出现原发昏迷,其中2只于损伤后20 min内死亡,余持续时间1-30 min不等;伤后大鼠呼吸节律紊乱,瞳孔对光反射减弱或消失,醒后均有程度不等的反应性下降,肢体活动迟缓;肉眼可见广泛蛛网膜下腔出血或脑室出血;光镜下可见皮髓交界区、胼胝体区、脑干、小脑白质等部位的神经轴索有不同程度的肿胀、断裂、轴索球形成,后期有小胶质细胞增生,局部呈巢样聚集。

The histological findings of the primary tumor and metastatic lymph nodes demonstrated massive cancer cell degeneration such as pycnosis and vacuolation, xanthogranulomatous inflammation and dense fibrosis. The effect of NAC was judged to be grade 2 histologically.

组织学检查发现肿瘤原发灶和转移的淋巴结癌细胞大量退化如核固缩和空泡形成,黄肉芽肿炎以及密集的纤维化,经组织学判定NAC的疗效为2级。

Recurrent primary diseases and implant autoproteolysis and infection more often result in graft perforation.

原发疾病的复发、角膜植片的自溶和感染常常导致角膜植片的穿孔。

Methods S-P immunohistochemical staining was used to detect the expression of VEGF-C and its reˉceptor Flt-4in10neighboring noncancerous tissue and60NSCLC cases of non-small cell lung cancer and32lymph nodes cases with lymph nodes metastasis of non-small cell lung cancer.

采用免疫组化S-P法检测60例NSCLC原发灶组织、10例癌旁组织、32例伴有肺癌转移的淋巴结组织中VEGF-C、Flt-4的表达,并将结果与肺癌的临床病理特征进行分析。

Methods S-P immunohistochemical staining was used to detec t the expression of VEGF-C and its reˉceptor Flt-4in10neighboring noncancerous tissue and60NSCLC cases of non-small cell lung cancer and32lymph nodes cases with lymph nodes metastasis of non-small cell lung cancer.

采用免疫组化S-P法检测60例NSCLC原发灶组织、10例癌旁组织、32例伴有肺癌转移的淋巴结组织中VEGF-C、Flt-4的表达,并将结果与肺癌的临床病理特征进行分析。

We describe a new technique using vascularized fibula grafts anastomosed to the internal thoracic vessels to reconstruct the cervicothoracic junction after en bloc resection of primary spinal tumors or for correction of progressive deformities in this region.

笔者描述一种新技术使用血管化腓骨移植物吻合到胸廓内血管重建颈胸结合部原发肿瘤整块切除后的缺损或矫正此区域的进行性加重的畸形。

Correct diagnosis were made in 34 malignancies and 6 false positive lesions were excluded based on moiphology and 18F-FDG uptake status of the lesion. There were 6 false positive and 2 false negative cases. Furthermore, extrathoracic metastases which were not showed on previous CT image in 4 patients including one in the adrenal gland and 3 in the bone were detected by 18F-FDG imaging.

根据形态及核素摄取特征,18F-FDG符合线路显像正确检出恶性病变34例,排除恶性病变6例,出现假阳性6例和假阴性2例,对原发肺癌诊断的灵敏度、特异性和准确性分别为94.4%、50.0%和83.3%;同时,在4例患者中检出了CT未发现的、发生于肾上腺和骨的肺外转移。

Chronic granulomatous disease, which is due to a primary defect of the phagocytic NADPH oxidase pathway, is one of the most common serious primary immunodeficiency syndromes, with an incidence of at least 1 in 200,000 births in the United States.

由于吞噬细胞NADPH氧化酶通路缺陷而致的慢性肉芽肿性病是最常见的严重原发免疫缺陷病,在美国的发生率是每200,000个出生儿中有1人。

METHODS Sixty-five cases of T3NOMO glottic squamous cell carcinoma treated with curative intent by three different modalities include vertical hemilaryngectomy(VHL, n=21), total laryngectomy (TL, n=31) and radiotherapy(RT, n=13) were reviewed retrospectively.

分析1992年~1999年我院采用喉垂直部分切除术、喉全切除术和根治性放射治疗等方案治疗的65例喉声门型癌T3NOMO病变的临床资料,比较不同治疗的总体生存率、原发部位及颈部淋巴结复发率和喉功能保留率。

The mean ADC value of lymphomatous, metastatic and benign lymph nodes was (0.874±0.17)×10~(-3)mm~2/s,(0.98±0.09)×10~(-3)mm~2/s and (1.20±0.10)×10~(-3)mm~2/s. There was statistically different between benign lymph nodes and other groups (P=0.00). When an ADC value of 1.085×10~(-3)mm~2/s was used as a threshold value for differentiating malignant from benign lymph nodes, the best results were obtained with an sensitivity of 87.8% and specificity of 91.3%. 16 of 18 cases (88.9%) were accurately staged in accordance with clinical staging. For 24 patients after chemotheraphy or radiotheraphy, 4 cases were complete remission and WB-DWI was negative. WB-DWI was positive in 14 of 17 cases with recurrent or remnant tumor. For 3 patients with suspected partial remission, WB-DWI indicated necrosis in 2 cases and inactive in 1 case. Repeated WB-DWI examination was performed in 13 cases, tumors were eradicated in 6 cases, improved in 4, expanded in 2. A new colon carcinoma besides its primary lesion was found in 1 case. The results of WB-DWI were all concordant with other clinical tests.

以ADC值1.085×10~(-3)mm~2/s作为诊断恶性淋巴结病变的临界值,敏感性及特异性分别为87.8%和91.3%。88.9%(16/18)患者WB-DWI检查后分期与临床分期一致。24例淋巴瘤患者放化疗后行WB-DWI检查,4例临床疗效为完全缓解,WB-DWI检查均为阴性,17例临床确认有肿瘤复发及明显残留,WB-DWI显示为阳性的14例,另外3例常规影像评价为部分缓解的患者,WB-DWI检查提示2例病灶以坏死液化为主,1例病灶无明显活性。13例淋巴瘤患者行多次WB-DWI检查,发现6例治疗后病灶消失,4例缓解,1例原发病灶缓解,新出现结肠癌,2例淋巴瘤进展,皆与临床相符。

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