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Granulosa cell apoptosis was a physiological phenomenon in follicles, and with the progress of atresia, the percentage of apoptotic granulose cells increased significantly.

颗粒细胞凋亡是卵泡中生理现象,随着卵泡闭锁凋亡颗粒细胞的比例增多。

Until now, only within the mouse model, the birth of live young have been reported.

在目前的技术条件下,啮齿类的腔前卵泡已能经体外培养发育至有腔卵泡期,而且从有腔卵泡分离的卵母细胞经体外成熟、体外受精后已能产生新的个体。

ResultsAfter three to six cycles of HT the serum FSH,LH level of 18 patients with recovery of mense dropped significantly,while E2 raised slightly. HMG/HCG and GnRH-a/HMG/HCG for ovulatory induce treatment have suceed in induciug follicular developrnent and mature,and one pregnancies.

结果 18例患者经雌孕激素治疗3~6周期后血清卵泡刺激素、黄体生成素水平明显下降,血清雌二醇(E2)升高不明显,以人绝经期促性腺激素HMG/人绒毛期促性激素的素方案和促性腺激素释放激素激动剂/HMG/HCG方案促排卵治疗有成熟卵泡发育,有1例妊娠。

Methods Transvaginal color Doppler flow imaging was employed to measure systolic maximal velocity,end-diastolic velocity,S/D ratio and resistant index of uterine and helicine artery in the follicle growth phase,follicle maturation phase,mid-luteal phase and advanced phase of luteal development.

方法应用经阴道彩色多普勒超声分别于月经周期的卵泡发育期、卵泡成熟期、黄体中期、黄体晚期观察测量子宫动脉及螺旋动脉收缩期峰值流速、舒张末期流速、收缩期/舒张末期流速比值及阻力指数。

Meanwhile to explore the influence of psychosocial stress factors on oocyte maturity, the number of retrieved oocytes and merogenesis, the plasma levels of A and NA and the follicular fluid levels of NA, estrogen and androgen were examined in pregnant and non-pregnant women.

并通过对妊娠与未妊娠妇女血浆中A、NA及卵泡液中NA、雌激素、雄激素水平测定,结合获卵数和卵裂数进行相关性研究探讨心理社会因素对卵泡发育成熟的影响。

The results showed that : 1 During nonbreeding season, the giant panda′s ovary was still rich with large and small follicular oocytes, and the large follicular oocytes could be matured in vitro; 2 The mean diameter of the oocytes was (141±6.7)μm and lots of cortical granules contained in the cytoplasm of oo...

结果表明∶(1)在非繁殖季节,大熊猫卵巢中小腔及大腔卵泡卵母细胞仍较丰富,其大腔卵泡卵母细胞可在体外培养成熟;(2)大熊猫的卵母细胞平均直径为(141±6.7)μm ,其胞质富含卵黄颗粒;(3)自配 PandaI I号获能液(含丙酮酸钠、肾上腺素等)可使大熊猫精子有效获能;(4)大熊猫卵母细胞体外受精后,经培养可观察到第2 极体,有的受精卵开始发生卵裂。

Do not cause decomposition of one ovulation, mature follicles to a certain stage, clearly highlighted in the ovarian surface, with the proliferation of follicular fluid, internal pressure increases, so that more and more prominent part of the ovarian tissue is thin, the final rupture secondary oocyte cells and their peripheral zona pellucida and corona radiata, together with the discharge of ovarian follicular fluid in the process called ovulation.

不排卵原因分解1、成熟卵泡发育到一定阶段,明显地突出于卵巢表面,随着卵泡液的激增,内压的升高,使突出部分的卵巢组织愈来愈薄,最后破裂次级卵母细胞及其外周的透明带和放射冠随卵泡液一起排出卵巢这一过程称排卵。

The arise of Ang II was found in thecal cells specially, the reason could be due to an abundance of blood vessels in the thecal cell layer, but not in the granulosa layer. E2, P, T may play very important roles in the follicle development and atresia.

RAS的变化主要发生在卵泡膜细胞,可能与卵泡膜细胞层具有丰富的血管而颗粒细胞层中无血管有关。E2、P、T具有不同程度的促进卵泡发育和抑制闭锁的作用。

(1)FM with an incidence of 27.0% might be an important cause of infertility.(2) FM results finally in follicular atresia or multiple immature luteinized follicles.

(1)FM是不孕的一个重要原因;(2)FM结局有二,一为卵泡闭锁,另一为未成熟卵泡黄素化。

Materials and Methods: We got the follicle fluid when eggs were withdrawed during IVF cycle and then separated and cultured luteinized granulosa cells using serum free medium.

IVF周期穿刺卵泡取卵时所得卵泡液,进行颗粒细胞分离培养,在无血清培养体系中加入不同浓度VEGF,观察基础状态下或HCG作用下培养液中〓、P浓度的变化。

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