卵泡的

After being dispersed by simply beat upon with syringe and adherent culture, the mature cumulus cells from mature OCCs in COH cycles, together with growth factors in the follicular fluid or extraneously supplemented, could promote the IVM of immature oocyte.

来自控制性促排卵周期的成熟卵丘细胞经简易吹打分散后贴壁培养，可能能协同卵泡液中或外加的生长因子，促进未成熟卵母细胞的体外成熟，而本研究技术简易有效，可用于挽救促排卵周期的未成熟卵。

Although several gametogenesis-specific genes were identified previously, more genes related to the ovarian development are expected to be involved due to the complexity of gametogenesis.

虽然已有一些调控卵子生长和卵泡发育的特异性基因被发现，但与卵巢发育和卵子生长相关的更多基因的功能有待于进一步研究，阐明其在这复杂过程中的具体分子机制。

A surge of luteinizing hormone from the pituitary gland triggers ovulation, oocyte maturation, and luteinization for successful reproduction in mammals.

在雌性的哺乳动物中，其脑垂体会释放出黄体生成素的每月一次的高峰。这些黄体生成素会与那些准备排卵的卵泡颗粒细胞结合。

The expression of Bcl-2 was weak or negative; there is no difference among various groups.Research Conclusion: lCadmium can accelerate the apoptosis of GCs and is related with dose; 2Cadmium accelerate atresic of follicular; and increase the number of interstitial gland;3Cadmium enhance the expression of bax, and no affect obviously on bcl-2;4 Selenium restrained the effect of cadmium-induced apoptosis on granulosa cells, but it cant be interdicted completely.

实验结论：1 镉能促进小鼠卵巢颗粒细胞凋亡，并具有剂量效应关系。2 镉能促进卵泡闭锁，使卵巢间质腺数量增加。3 镉能增强颗粒细胞凋亡相关基因bax的表达，对bcl-2的表达则无明显影响。4 硒具有一定的抑制镉致颗粒细胞凋亡的作用，但不能完全阻断。

The new GV preparation method we developed allowed the best visualization of chromatin distribution after Hoechst or CMA3 staining. Our results showed that GV chromatin configurations are different among different species, and thus, while chromatin condensed into a ring around the nucleolus in porcine and bovine oocytes, no such a ring was observed in caprine oocytes; Porcine oocytes were synchronized at GV1, goat oocytes at GV3n and bovine oocytes at GVf configurations before GVBD occurred, indicating that these configurations are progressive towards final maturation rather than atresia; Changes of chromatin configurations were associated with gene activity of transcription; GV chromatin configurations were affected by the environmental changes such as serum starvation and elevated temperature.

应用该技术对猪、山羊和牛不同大小、不同健康程度卵泡及体内和体外成熟过程中卵母细胞染色质构型的变化发现：1）不同动物卵母细胞染色质构型不同；猪和牛卵母细胞染色质围绕核仁凝集形成环，但山羊卵则没有此环。2）卵母细胞在GVBD之前都同步在某一染色质构型；猪同步在GV1，山羊GV3n，牛GVf，说明这些染色质构型代表着进行性变化。3）染色质构型的变化反映基因转录活动的变化。4）染色质构型受环境变化的影响。

Regulation of follicular development and atresia is a complicated process,including the interaction of endocrine factors,ovarial regulatory factor and nutritional factors during the controlling of the ovocyte fate.

卵泡发育和闭锁的调节是一个复杂的过程，包括内分泌因素、卵巢内调节因子及营养因素在控制卵母细胞的命运中的相互作用。

Normal gonadal steroid production requires the actions of the pituitary-derived gonadotropins, luteinizing hormone and follicle-stimulating hormone.

正常的性激素产生需要垂体产生的促性腺激素，促卵泡激素的作用。

Histopathology observation of ovaries revealed that the ovulations decreased in females may be due to the follicular tresia.

卵巢的组织病理学观察认为，母鼠的排卵数减少是由于卵泡发育过程中出现闭锁退化的结果。

Compared with their thinner counterparts, obese men had lower levels of testosteroe in their blood, as well as lower levels of luteinizing hormone and follicle-stimulating hormone -- both essential to reproduction.

和瘦的受试者相比，肥胖男性血液中的睾酮水平较低，同时促黄体激素和促卵泡激素的水平也较低，这两种激素对生育至关重要。

And inhibin in male animal s can selectively inhibit the secretion of FSH and conduct the cooperation with testosterone.

抑制素主要是由雄性动物的睾丸支持细胞和雌性动物的卵泡颗粒细胞所分泌的一种糖蛋白。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。