卵泡

Until now, only within the mouse model, the birth of live young have been reported.

在目前的技术条件下，啮齿类的腔前卵泡已能经体外培养发育至有腔卵泡期，而且从有腔卵泡分离的卵母细胞经体外成熟、体外受精后已能产生新的个体。

Objective To study the differentially expressed proteins between mature and antral follicles and identify the proteins crucial for follicle development and oocyte fertilization.

目的 应用蛋白质芯片和质谱技术，建立人成熟卵泡液及窦卵泡液的蛋白质表达指纹图谱，寻找在卵泡生长发育过程中起关键作用的蛋白质。

Results In comparison with those in the antral follicular fluid, the concentration of 4 proteins were significantly different in mature follicular fluid, including two up-regulated and two down-regulated proteins.

结果 成熟卵泡液组与窦卵泡液组蛋白质谱相比，有4种蛋白质在含量上有显著差异，2种蛋白质在成熟卵泡液组表达上调，2种蛋白质表达下降。

Immune POF model elicited by immunization in subcutaneous with antigen sourced isotype animal ovaries can cause growing follicles and mature follicles decrease obviously, the morphology of oocytes and zona pellucida abnormal, the adjacent granular cells disorder and atresic follicle increase.

以同种动物卵巢为抗原主动免疫建立的免疫性POF模型可致生长卵泡和成熟卵泡数明显减少，卵母细胞及透明带形态异常，周边颗粒细胞排列紊乱，闭锁卵泡增多，病理损伤随免疫时间延长而加重。

The rates of apoptotic granulosa cells in all kinds of follicles in immature gilts were ashigh as atretic follicles;it decreased significantly after injection of PMSG,but it was higherand lasted shorter than that of mature pig.

性未成熟仔母猪卵巢中各类卵泡颗粒细胞凋亡比例很高，接近闭锁卵泡的凋亡比例；注射PMSG后则各类卵泡颗粒细胞凋亡比例显著下降，但高于性成熟母猪注射PMSG后的凋亡比例，并且维持的时间也较短。

The BMP15 protein played a certain role in all the stages of follicular development and had a relationship with the luteal dissolution mechanism; In the atretic follicle, the low expression of BMP15 protein maybe caused by inhibition from the other factors which lead to connected modification of follicular atresia.

结论］BMP15参与了兔卵泡发育全过程，并且与黄体溶解机制有关；而在闭锁卵泡中，其低水平的表达可能是由其他因子所抑制，进而共同调节了卵泡的闭锁。

The vast majority of follicles undergo a degenerative process in reproductive life. Apoptotic cell death is the fundamental mechanism in response to follicular atresia. Moreover, the apoptosis of granulose cells is implicated in directly mediating atretic process. Multiple studies have confirmed that the apoptotic process of GCs is not only related to apoptotic genes, but triggered by cytokines related to reproduction and Caspases family.

中文题名几种生殖激素对体外培养的牦牛卵泡颗粒细胞凋亡的影响副题名外文题名 Effects of several reproductive hormones on apoptosis of ovarian granulose cells of yaks in vitro 论文作者杨世华导师余四九教授学科专业临床兽医学研究领域\研究方向学位级别博士学位授予单位甘肃农业大学学位授予日期2002 论文页码总数108页关键词牛类固醇激素分泌卵泡颗粒细胞培养牦牛生殖激素馆藏号BSLW /2003 /S823 /1 卵泡闭锁是哺乳动物卵巢中极为普遍的自然现象。

Results: The level of serum trace elements of Cu, estradiolum and testosterone in model group was obviously higher than that of control group, the ovarian follicle of model group was ectatic and the granular layer was very thin. There were abundant all-growth period follicle and corpus luteum in ovary in normal rats.

结果：与时照组比较，模型组大鼠血清Cu、E2、T含量明显增加(P.01)；卵巢组织形态学观察：对照组可见各期发育卵泡及黄体形成，模型组卵泡呈囊性扩张，颗粒细胞层明显减少，大量卵泡闭镇。

Cell adhesion and extra cellular matrix in follicles also play an important intraovarian role.

卵泡闭锁的实质就是卵泡中发生了细胞凋亡，其中卵泡颗粒细胞凋亡是导致卵泡闭锁的直接诱因。

The size of follicle begin primordial follicle to tertiary follicle(1.5～3mm).The number of mitochondrion increased,and the cristae increased.Gogi body change to type,cortical granule increased,and moved behind cytolemma.The proportion of small,middle and large follicles on ovary were 92.51%(92.51±5.87),4.60%(4.60±4.91) and 2.88%(2.88±2.22) respectively.

卵泡在发育过程中，卵泡细胞形成的突起与卵母细胞始终保持密切的联系：卵母细胞从原始卵泡到直径1.5～3mm的三级卵泡，细胞质中线粒体数量由少到多，线粒体内的嵴不断增加，高尔基体由不典型到变成典型，皮质颗粒由开始形成到形成较多的皮质颗粒，并逐渐地迁移到卵母细胞膜下。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。