卵泡

Patients: Patients included 12 healthy young women during the early follicular phase of two subsequent cycles.

患者：患者包括处于两个后续循环的卵泡早期12位年轻健康女性。

The rising estrogen level also stimulates the growth of some of the Graafian follicles that encase the immature ova.

雌激素水平升高也刺激一些卵泡生长。

The rising estrogen level also stimulates the growth of some of the Graafian follicles that encase the immature ova.

雌激素水准升高也刺激一些卵泡生长。

The improved puberty PCOS-IR rat model has following characteristic:Retained the high androgen syndrome and/or the high LH syndrome as the endocrine characteristics;Simultaneously it had sugar fat metabolism unusual, such as the insulin resistance,the redemptive high insulin blood sickness as well as cholesterol ascension.Has the abdomen obese characteristic----In particular fat pad which around reproductive organ obvious increased;The ovary increased obviously,Ovarian cortex accumulated,the number in ovary pouch expansion graafian follicle were remarkable increased, ovulation suppression.

一、改良青春期PCOS-IR大鼠模型具有以下特征：1、保留了高雄激素血症和/或高LH血症等内分泌特征；同时有胰岛素抵抗，代偿性高胰岛素血症以及总胆固醇升高的糖脂代谢异常。2、具有腹部肥胖的特征——尤其是生殖器周围脂肪垫明显增加；3、卵巢明显增大，皮质增厚，卵巢内囊性扩张卵泡数目显著增加，排卵抑制。

No cPGES mRNA signal was detected in granulosa cells.

在PMSG处理后的卵泡颗粒细胞中，几乎检测不到cPGES免疫染色。

CPGES mRNA signal was maily located in oocyte cytoplasm and declined at 48 hafter PMSG treatment.

在各级卵泡的卵母细胞质中有很强的cPGES免疫染色，仅在PMSG注射48小时，在卵母细胞质中的cPGES免疫染色有所下降。

When the max follicle diameter was ≥18 mm, the women were injected with human chorionic gonadotropin 10000 U intramuscularly.

至最大卵泡平均直径≥18 mm时，肌注人绒毛膜促性腺激素

Plenty of studies have been made towards unraveling the complex intraovarian control mechanisms that act in concert with systemic signals to solve some clinical problems, improve the outcome of assisted reproductive technology and establish the in vitro maturation system.

许多研究致力于探索卵泡发育的正常生理精确过程，以更好的了解人类配子发育过程及生殖奥秘，更好的解决一些临床疾病；在辅助生育技术(Assistant reproductive technology，ART)中提高临床妊娠率，建立完善的体内外卵子成熟的体系，这是人类生殖研究中一个重要课题。

The indexes are as follows:(1)The effect of acupuncture combined with herb on peripheral serum estradiol (E2), calcitonin,osteocalcin,parathyroid hormone, testosterone, follicle stimulating hormone , luteinizing hormone, The serum E2, CT, BGP, PTH ,T ,FSH and LH levels were estimated by radioimmunoassay with the blood of elbow vein.(2) Adopt the improved method of Kupper grade point, to estimate symptom.

2治疗前后均抽取患者肘静脉血作雌二醇（E2）、降钙素、骨钙素、甲状旁腺激素、睾酮、卵泡刺激素、黄体生成素放免测定(3)采用改良的Kupper评分法，进行症状体征评分。

Result: The expression of EG-VEGF mRNA was much higher than VEGF mRNA in both follicular and luteal phase P

结果：(1) RT-PCR发现卵泡期和黄体期的EG-VEGF mRNA表达均高于VEGF mRNA，差异有统计学意义P

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。