卵巢癌

Methods: The expression of p16 protein and nm 23 protein were detected by an immunohistochemistory assay in 130 cases of tissue samples including 30 normal ovary, 50 ovarian benign epithelioma and 50 ovarian epithelial carcinoma.

免疫组化SP法检测30例正常卵巢，50例卵巢上皮性良性肿瘤及50例卵巢癌组织中P16蛋白和nm23蛋白，并分析其阳性表达与肿瘤的关系。

Methods: The expression of P16 protein and nm23 protein were detected by streptavidin peroxidase conjugated method in 78 cases of tissue samples including 12 normal ovary,14 ovarian benign epithelioma and 52 OEC.

免疫组化S P法检测12 例正常卵巢，14 例卵巢上皮性良性肿瘤及52 例卵巢癌组织中 P16 蛋白和nm 23 蛋白的表达。

Thyroid transcription factor-1 in normal, hyperplastic, and neoplastic follicular thyroid cells examined by immunohistochemistry and nonradioactive in situ hybridization.

本实验TTF-1在所有转移性腺癌中的敏感性为35.3%（18/51），特异性为100%（0/36），在肺腺癌中的敏感性为61.5%（16/26），特异性为91.7%（22/24），有2例肺外腺癌表达TTF-1，1例为乳腺癌，另1例为卵巢癌。

"Prophylactic oophorectomy should not be recommended to women with a high risk of breast cancer who do not have documented mutations in BRCA1 or BRCA2, since these cases may be linked to mutations in unidentified genes that do not increase the risk of ovarian cancer," he writes."The effectiveness of prophylactic oophorectomy in carriers of BRCA mutations provides a strong rationale for genetic testing in women with a strong family history of cancer."

不应该对乳腺癌发生危险较高，但没有明确的BRCA1或者BRCA2突变的女性，推荐进行预防性卵巢切除术，因为这些情况也许与未知的，与卵巢癌的发生无关的基因突变有关，」他写道：「对於BRCA突变体携带者进行预防性卵巢切除术，为有很强的肿瘤家族史的女性，进行遗传学检查，提供了强有力的依据。

Overexpression of PAKI protein may be involved in the tumorigenesis of epithelial ovarian neoplasms and it is associated closely with the malignant histological phenotype of ovarian carcinomas.

结论PAK1蛋白过度表达可能在卵巢上皮性肿瘤的发生发展中起重要作用，而且与卵巢癌的恶性组织学表型密切相关；在卵巢肿瘤PAK1蛋白的表达调控中，基因扩增以外的其他调节机制可能起更为关键的作用。

Results 80 cases of female pelvic masses,among them 8 cases ectopic pregnancy,16 cases leiomyoma of uterus,12 cases ovarian cyst,10 cases teratoma of ovary,12 cases oophoroma,8 cases ondometrial carcinoma and 12 cases cases cervical carcinoma.

功效 80例女性盆腔包块，其中异位妊娠8例，子宫平滑肌瘤16例，卵巢囊肿12例，卵巢畸胎瘤10例，卵巢癌14例，子宫内膜

Kb, the cDNA length is 6022 bases, the PPO amino acid sequence has the genes of the open-reading frame of 993 amino acid residues, the gene is expressed in multiple tissues of human cancer, including oophoron cancer, mammary cancer, pancreas adenocarcinoma, colon cancer, lung carcinoma and prostate cancer.

PPO的氨基酸序列具有编码SEQ ID NO.2所示的993个氨基酸残基的可读框的基因。该基因在人类多种癌组织中(卵巢癌，乳腺癌，胰腺癌，结肠癌，肺癌，前列腺癌，脑癌，胃癌，肝癌，子宫癌等)都有过表达。活性成份可制备成癌症诊断剂或试剂盒。

With the aim of elucidating features which may help with differential diagnosis, this study reports the incidence and pathologic features of benign ovarian alterations, benign ovarian tumors, and occult primary and metastatic malignancies in prophylactic oophorectomies from 108 women with a BRCA mutation and from 35 women with other strong risk factors for hereditary breast/ovarian carcinoma.

为了阐明鉴别诊断的要点，本研究报道了卵巢良性病变、良性肿瘤和隐匿性原发性及转移性恶性病变的发生率和病理特征，所选病例都做了预防性卵巢切除术，包括108例伴有BRCA基因突变的女性和35例伴有其他遗传性乳腺/卵巢癌高危因素的女性。

The recombinant TFPI-2 inhibits the invasive ability of human ovarian tumor cells in vitro, but has no effect on the migration, Which may provide a target basis for treating human ovarian tumor with TFPI-2 protein therapy.

重组TFPI-2对人卵巢癌细胞体外自身运动能力无影响，但可显著抑制人卵巢癌细胞的体外浸润能力，为将来卵巢癌用蛋白酶抑制剂治疗提供一可能的靶向依据。

In their prospective study of 170 carriers of BRCA1 or BRCA2 mutations with a mean follow-up of 2 years, ovarian cancer or a papillary serous carcinoma of the peritoneum developed in 5 of 72 women (6.9%) who elected intensive surveillance. Of 98 women who had prophylactic salpingo-oophorectomy, 3 (3.1%) had early-stage tumors diagnosed at surgery, and 1 (1.0%) developed primary peritoneal cancer during follow-up.

此次包括170位BRCA1或者BRCA2突变体携带者，平均随访时间为2年，进行密切检测的72位女性中，5位(6.9%)患者发生卵巢癌或者血性腹膜乳头瘤，而进行预防性卵巢切除术的98位女性中，有3人(3.1%)手术诊断已经患有早期肿瘤，有1人(1.0%)在随访期间发生腹膜癌。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。