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But when his group stratified the cohort by mutation status, they observed differences in risk reduction."These results also generate the hypothesis that the protection conferred by risk-reducing salpingo-oophorectomy against specific cancers may differ between carriers of BRCA1 and BRCA2 mutations," Dr. Kauff told attendees."We found that it is highly protective against BRCA -associated gynecologic cancer in both 1- and 2-mutation carriers." And in breast cancer, his team observed a protective effect in BCRA 2 mutations.

当他的团队统计研究对象的突变状态时,他们观察到风险降低的差异性;Kauff医师向与会听众表示,这些结果也产生了藉由风险降低的输卵管卵巢成形术,对特定癌症所提供的保护效果或许会因BRCA1和BRCA2载体突变而有差异的假设;我们发现对这两种载体突变可以高度有效地对抗BRCA有关的妇科癌症;至于乳癌,他的团队观察到在BCRA2突变有保护效果。

But when his group stratified the cohort by mutation status, they observed differences in risk reduction."These results also generate the hypothesis that the protection conferred by risk-reducing salpingo-oophorectomy against specific cancers may differ between carriers of BRCA1 and BRCA2 mutations," Dr. Kauff told attendees."We found that it is highly protective against BRCA -associated gynecologic cancer in both 1- and 2-mutation carriers." And in breast cancer, his team observed a protective effect in BCRA 2 mutations.

当他的团队统计研究对象的突变状态时,他们观察到风险降低的差异性;Kauff医师向与会听众表示,这些结果也产生了藉由风险降低的输卵管卵巢成形术,对特定癌症所提供的保护效果或许会因BRCA1和BRCA2载体突变而有差异的假设;我们发现对这两种载体突变可以高度有效地对抗BRCA有关的妇科癌症;至於乳癌,他的团队观察到在BCRA2突变有保护效果。

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