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卵巢妊娠

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Methods We made a retrospective analysis on the clinical symptoms, diagnosis and treatment process of seven cases of ovarian pregnancy, which were collected from 1990 to 2005Results Every patient manifested bellyache when ovarian pregnancy was coming on.

对本院1990—2005年间收治的7例卵巢妊娠,结合文献对其临床表现、诊断与治疗过程进行回顾性分析。

Objective To analyze the clinical characteristics of ovarian pregnancy.

目的 分析卵巢妊娠的临床特征。

In order to investigate the effect of IFN-γon the expression of TNF-αin the hypothala- mus-pituitary-ovary axisof RU486-induced aborted SD rats, RU486 was used to establish the abortion model, then the aborted rats were administrated with different doses of IFN-γintraperitoneal injection, the method of immunohistochemical ultrasensitive SP was us- ed to study the variation of positive TNF-αcells in hypothalamus, pituitary, ovary and uterus in normal pregnant group A, aborted model group B and three different doses of IFN-γgroup C,D,E. The main goal of this research was to study whether the low dose of IFN-γcould have a protective function to pregnancy and the mechanism of its function so as to provide morph- ologic basis for the scientific using of IFN-γin the process of animal abortion control.

为探讨IFN-γ对流产大鼠下丘脑-垂体-卵巢轴(hypothalamus-pituitary- ovary-axis,HPOA )TNF-α表达的影响,本试验用米非司酮(RU486)建立SD大鼠流产模型,通过腹腔注射不同剂量IFN-γ,采用超敏感免疫组织化学SP法(链霉素抗生物素—过氧化物酶法),观察了孕13天(d13)SD大鼠正常妊娠A组、流产模型B组、不同剂量IFN-γC、D、E组下丘脑、垂体、卵巢、子宫TNF-α的表达变化,探讨低剂量IFN-γ对妊娠是否有保护作用及其作用机制,期望能为在妊娠过程中如何科学应用IFN-γ防止动物流产提供形态学依据。

Methods:The data of 52 cycles of IVFET, which were accomplished in the Reproductive Medicine Center of First Affiliated Hospital, Sun Yat-sen University during February 1999 and April 2001, from 45 patients with history of unilateral salpingectomy clue to ectopic pregnancy, were analyzed retrospectively.

本研究分析因输卵管妊娠行单侧输卵管切除后不孕在我院生殖中心接受体外受精一胚胎移植(in vitro fertili:ation and embryotransfer,IVF一ET)治疗的资料,比较输卵管切除侧卵巢与对侧卵巢对超排卵的反应性,为输卵管妊娠及输卵管积水的处理提供临床资料。

Hydrosalpinx is detrimental to the outcome of IVF-ET and may cause the increase of abortion,appropriate procedure should be adopted to deal with the problem before the IVF-ET and may improve the outcome of IVF-ET and may decrease the abortion rate.Compared with the salpingectomy,the proximal tubal ligation with distal tubal salingostomy may be a better option in this situation and it may cause less interference to the ovarian function.

输卵管积水对IVF-ET有不良影响,增加了流产率及异位妊娠率,在IVF-ET前对输卵管积水进行适当的处理有助于提高临床妊娠率,降低流产率;与输卵管切除术相比,输卵管近端结扎伞端造口术对卵巢功能影响较小,不增加流产率及异位妊娠率。

Objective To explore the value of laparoscopic operation in the treatment of gynecologic diseases.Methods Retrospective analysis of 170 cases of laparoscopic surgery in ynecology.53 cases in the salpingocyesis group,49 cases salpingotomy,4 cases salpingectomy;48 cases in the ovarian cyst group,35 cases enucleation and repair of ovary,8 cases ovary sutures atches,3 adnexnectomy and 2 perforation of ovary;52 cases in the uterine problems group,10 cases LM5 cases CISH,11 cases LSH(laparoscopic supracervical ysterectomy),14 cases LTH(laparoscopic total hysterecotomy),12 cases LAVH laparoscopically assisted vaginal hysterectomy);17 cases in the infertility group were studied in terms of lysis of pelvic adhesions and salpingostomy.

目的 探讨妇科腹腔镜手术的临床应用价值方法回顾性分析170例妇科腹腔镜手术病例,其中异位妊娠组53例,行输卵管切开取胚49例,输卵管切除术4例;卵巢疾患组48例,囊肿剥除术及卵巢成形术35例,卵巢缝合修补8例,患侧附件切除3例,囊卵巢多点打孔2例;子宫疾病组52例,行肌瘤剥除10例,改良CISH术5例,子宫次全切除术11例,子宫全切术14例,腹腔镜辅助阴式子宫切除12例;不孕症组17例,行盆腔粘连分解输卵管伞造口术。

Methods Retrospective analysis of 170 cases of laparoscopic surgery in ynecology.53 cases in the salpingocyesis group,49 cases salpingotomy,4 cases salpingectomy;48 cases in the ovarian cyst group,35 cases enucleation and repair of ovary,8 cases ovary sutures atches,3 adnexnectomy and 2 perforation of ovary;52 cases in the uterine problems group,10 cases LM5 cases CISH,11 cases LSH(laparoscopic supracervical ysterectomy),14 cases LTH(laparoscopic total hysterecotomy),12 cases LAVH laparoscopically assisted vaginal hysterectomy);17 cases in the infertility group were studied in terms of lysis of pelvic adhesions and salpingostomy.

回顾性分析170例妇科腹腔镜手术病例,其中异位妊娠组53例,行输卵管切开取胚49例,输卵管切除术4例;卵巢疾患组48例,囊肿剥除术及卵巢成形术35例,卵巢缝合修补8例,患侧附件切除3例,多囊卵巢多点打孔2例;子宫疾病组52例,行肌瘤剥除10例,改良CISH术5例,子宫次全切除术11例,子宫全切术14例,腹腔镜辅助阴式子宫切除12例;不孕症组17例,行盆腔粘连分解输卵管伞造口术。

Methods: The clinical data of 41 patints with rare ectopic pregnancy including interstitial pregnancy.23 cornual uterogestation,9 ovarian pregnancy,4 abdominal,2 pregnancy were retrospectively analyzed,deformity uterogestation,1 intramural pregnancy,1 and nub of fallopian tube pregnancy,were retrospectively analyzed.

回顾 分析 2003年7月至2005年10月经腹腔镜手术治疗的特殊部位异位妊娠41例的临床资料,包括输卵管间质部妊娠23例,宫角妊娠9例,卵巢妊娠4例,腹腔妊娠2例,残角子宫妊娠1例,子宫肌壁间妊娠1例,输卵管残端妊娠1例。

All results above indicated that:The expression of ERβand p-ERβin mouse ovary at oestrous cycle and in early gestational period changed regularly, it showed that ERβand p-ERβhad important effects to ovaries development, ovarian follicles groth, oocyte maturation and form corepus luteum in female mouse ovary during oestrous cycle and in early gestational period.

以上结果表明:ERβ及其磷酸化形式——p-ERβ在小鼠发情周期以及妊娠早期卵巢中表达有规律性的变化,揭示ERβ与p-ERβ在雌性小鼠发情周期及妊娠早期,对卵巢发育、卵泡生长、卵母细胞成熟和黄体形成有重要的作用。

It was shown that: 1 MMP2 activity reached the highest level during proestrus, and was lowest during diestrus; 2 MM2 acti vity was increased from the first day of pregnancy, peaked on day 4 of pregnancy; but decreased significantly at day 7 of the pregnancy. 3 MMP2 activity was obviously higher on day 1 of pseudopregnancy than on the other days, and its activity decreased gradually, reached the very low level at day 4 of pseudopregnancy and maintained the low level until day 7; 4 MMP2 activity was decreased significantly 24 hours after injection of 17βestradiol ( 01 mg) at metaestrus, while MMP2 activity had no change after progesterone (04 mg) injection.

明胶酶A活性变化如下:1在大鼠的动情前期明胶酶A的活性最高,间情期最低;2在妊娠早期(1~7天)的卵巢中,明胶酶A的活性在妊娠第4天达到最高,第1~3天及第5、6天其活性也较高,但第7天则明显下降;3在假孕(1~7天)大鼠的卵巢中,明胶酶A的活性在假孕第1天最高,第2、3天略下降,从第4天到第7天,其活性都处于较低水平;4动情后期大鼠皮下注射雌二醇(0.1mg/只)24小时后,明胶酶A活性明显上升。

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