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Estrogen can effectively prevent bone loss by inhibiting osteal formation and resorption and decreasing bone transformation in ovariectomized rats, which may be related to the increased transcription of renal VDR.

雌激素能有效地抑制去卵巢大鼠的骨吸收和骨形成,降低骨转换,可能与促进去卵巢大鼠肾脏VDR mRNA的表达有关。

Results: OVX group, with weakened bone structure, had decreased cancellous bone and increased parameters of osteal formation and resorption compared with Sham, OVX+E and OVX+E+P groups(P.05). The bone mass, osteal formation and resorption in group OVX+P had no significant changes.

结果:与假手术组、雌激素及雌孕激素组相比,去卵巢大鼠松质骨骨量明显减少,伴有骨结构变差,骨形成和骨吸收的参数值增加(P.05);与去卵巢组相比,孕激素组大鼠无显著改变。

Objective:To study the difference between the normal tissue and carcinoma of ovary,set up the proteome atlas of ovarial carcinoma then lay a foundation of early diagnosis in clinic.

目的:研究卵巢正常、恶性肿瘤组织蛋白质表达的差异,构建卵巢恶性肿瘤组织的蛋白质表达谱,为临床早期诊断奠定基础。

Methods 42 patients with three-stage of ovarial epithelium carcinoma who underwent ovarian cancer reduction operation were randomly divided into two groups.20 patients in the control group accepeted Cisplatin-based combination chemotherapy for six months.22 patien...

方法将42例接受卵巢癌肿瘤减灭术治疗的Ⅲ期卵巢上皮性癌患者随机分为治疗组22例和对照组20例。

The levels of serum gonadal hormone were detected by radioimmunoassay. The effects of ZYJN on ovaries and ovarial follicular development were observed by light microscope. The expressed level of LIF was detected by using the immunohistochemical staining technique.

随机分为对照组、PCO模型组、PCO模型组+助孕胶囊组、PCO模型组+克罗米酚组,采用放免法测定血性激素水平的变化,光镜观察卵巢、卵泡发育的情况,免疫组化法检测卵巢组织LIF的表达水平。

Methods The PCO rat models, prepared by pregnancy hormone combine with human chorionic gonadotrophin, randomly divided into four group as control, model, Chinese crude drug and western medicine group; The levels of serum gonadal hormone were detected by radioimmunoassay; The effects of ZYC on ovaries and ovarial follicular development were observed by light microscope; And the expression level of TNF-α was detected with the immunohistochemical staining technique.

采用孕激素联合人绒毛膜促性腺激素造模法制备PCO模型大鼠。随机分为对照组、PCO模型组、PCO模型组+助孕胶囊组、PCO模型组+克罗米酚组,运用放免法测定血清性激素水平的变化;光镜观察卵巢、卵泡发育的影响,免疫组化学法检测卵巢组织肿瘤坏死因子α表达水平。

In order to understand the mechanisms of livial in prevetion of bone loss in patients with premeture ovarin failure.12 cases pstients were treated with livial for two months.Then fasting urinary calcium creatinine ratio、 hydroxyproline creatinine natio、 Serum akaline phosphotase、 estradio(E2)、 Calcitonin、 bone gla-protein and interleukin-6(IL-6) were determined for these patients before and after treatment.

本文通过给12例卵巢早衰患者利维爱用药2个月,并于给药前后分别测定空腹尿钙与肌酐、羟脯氨酸与肌酐比值以及血清碱性磷酸酶、雌二醇(E2)、骨钙素、降钙素和白细胞介素-6(IL-6)的水平,以探讨Livial防止卵巢早衰患者骨量丢失的作用机制。

Objectives To investigate the changes of ovarian function after uterectomy in women with unilateral ovary or bilateral ovarium reserved.

方法选取因子宫良性病变在45岁前行子宫切除,保留双侧卵巢的36例为A组,保留单侧卵巢的25例为B组(两组术后时间均为5年),选取正常妇女23例为对照组。

Objective: To investigate the morphologic and hormonal changes in the ovarium of polycystic ovarian syndrome rat model induced by dehydroeplandrosterone,and the relationship between PCOS and insulin resistance.

提要 目的:研究脱氢表雄酮诱导SD幼年雌性大鼠多囊卵巢综合征动物模型的卵巢形态学及性激素变化,同时探讨其与胰岛素抵抗方面的关系。

Objective: To investigate the morphologic and hormonal changes in the ovarium of polycystic ovarian syndrome rat model induced by dehydroeplandrosterone,and the relationship between PCOS and insulin resistance.

目的 :研究脱氢表雄酮诱导SD幼年雌性大鼠多囊卵巢综合征动物模型的卵巢形态学及性激素变化,同时探讨其与胰岛素抵抗方面的关系。

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