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Objective To detect the expression of basic fibroblast growth factor and E26 transformation specific 1(Ets 1) in primary ovarian carcinoma to provide new evidence for understanding the biological behavior of primary ovarian carcinoma.

目的检测碱性成纤维细胞生长因子(basicfibroblastgrowthfactor ,bFGF)和E2 6转录因子(E2 6transformation specific 1 ,Ets 1 )在原发性卵巢癌中的表达,为评估卵巢癌的生物学行为提供新的依据。

GPC3 pro tein was doubly or trebly expressed in normal ovarian tissues compared with ovarian carcinomas.

GPC3蛋白在正常卵巢组织中的表达水平是卵巢癌组织中的2-3倍。

Objectives To investigate the changes of ovarian function after uterectomy in women with unilateral ovary or bilateral ovarium reserved.

目的探讨子宫切除对保留双侧与单侧卵巢卵巢功能的影响。

ERαhad a weaker expression inraloxifene of 1mg/kg/d with estradiol valerate of 0.02mg/kg/d group than the othergroups 1 Raloxifene combined with different estradiol dosages hasdemonstrated the same protecting effect on bone as raloxifene alone. Combinedadministration does not decrease the protecting effect. 2 Raloxifene combined with different estradiol dosages has not demonstratedstimulatory effect on uteri and breasts and has maintained normal aorta structure.

1雷洛昔芬和不同剂量雌激素配伍对去卵巢大鼠的股骨效应与雷洛昔芬相同,两种药物合用不减弱对骨的保护作用。2雷洛昔芬和不同剂量雌激素配伍对去卵巢大鼠的子宫和乳腺无刺激性,能够维持主动脉内皮和平滑肌的正常形态和功能。

On the 14th day after yolk sac had disappeared, gonad had differentiated to ovary.

生殖腺中卵的成熟及卵巢腔的形成是「由前往后之层次」成熟,在卵黄囊消失后第四十九天的鱼苗,卵巢的发育至周边核仁期。

A summary was given to 35 cases of gynecologic operation ( the success rate was 100%), including ovarian tumor removal under TV abdominoscope, adnexectomy, oviducal ectopic gestation, ostomy of fimbria end of fullopian tube (with tubal patent test by liquid instillation on two sides), lytic operation for pelvic adhesion, avarian endometriosis and sterilizing operation.

总结在电视腹腔镜下行卵巢囊肿剔除术、附件切除术、输卵管异位妊娠手术、输卵管伞端闭锁造口、盆腔粘连分开术和并盆腔、卵巢子宫内膜异位症和绝育手术共 3 5例资料,成功率为 10 0 %。

Polycystic ovary syndrome , one of the most common endocrine diseases affecting women of reproductive age, plays an important role in anovulatory infertility, with a prevalence of up to 5%~21%; The main clinical manifestations include irregular menstruation (amenorrhea or infrequent menstruation or dysfunctional uterine bleeding), infertility, hirsutism, obesity and acanthosis nigricans. Elevated serum LH levels and hyperandrogenism, insulin resistance with compensatory hyperinsulinemia are its endocrinological features. Polycystic ovary morphology is also a common feature in PCOS. With the advance researches, PCOS displays its complexity and essential trend.

多囊卵巢综合征(polycystic ovary syndrome,简称PCOS)是育龄期妇女最常见的内分泌紊乱性疾病之一,在不排卵性不孕中占主要地位,发病率约5%~21%;主要表现为月经异常、不孕、多毛、肥胖及黑棘皮征,以高雄激素血症、促性腺激素异常、高胰岛素血症及胰岛素抵抗等内分泌学特征,以双侧卵巢增大呈囊性改变并间质增生为病理形态学基础的多系统疾病。

The uncomfortable syndrome in the periods of menses was owing to the pelvic diseases such as pelvic inflammation, adenomyoma, endometriosis, ovarian cyst, poly cystic ovary, pelvic adhesion.

临床上月经疼痛通常分为原发性及继发性两种,原发性是指没有任何骨盆腔疾病情况下发生的经痛,继发性则是指因为其他疾病所引起的经痛,又称之为病理性经痛,也就是骨盆腔疾病所导致的疼痛,例如骨盆腔发炎、子宫肌腺瘤,子宫内膜异位,卵巢囊肿,多囊性卵巢、臂,盆腔黏连等等。

aim: to evaluate the effects of combined therapy of phosphatidylinositol 3 kinase (ly294002) and paclitaxel in athymic mice xenogeneic transplant model of ovarian cancer.

目的:观察磷脂酰肌醇3 激酶抑制剂ly294002联合紫杉醇对裸鼠卵巢癌的抗肿瘤作用,为临床治疗中晚期卵巢癌提供实验资料。

The expression of Bcl-2 was weak or negative; there is no difference among various groups.Research Conclusion: lCadmium can accelerate the apoptosis of GCs and is related with dose; 2Cadmium accelerate atresic of follicular; and increase the number of interstitial gland;3Cadmium enhance the expression of bax, and no affect obviously on bcl-2;4 Selenium restrained the effect of cadmium-induced apoptosis on granulosa cells, but it cant be interdicted completely.

实验结论:1 镉能促进小鼠卵巢颗粒细胞凋亡,并具有剂量效应关系。2 镉能促进卵泡闭锁,使卵巢间质腺数量增加。3 镉能增强颗粒细胞凋亡相关基因bax的表达,对bcl-2的表达则无明显影响。4 硒具有一定的抑制镉致颗粒细胞凋亡的作用,但不能完全阻断。

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