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博莱霉素

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Objectives To study the expressions of STAT1 and PDGF in lung tissue of pulmonary fibrosis model induced by bleomycin in rats, and discuss the possible mechanism.Methods Thirty Wistar rats were randomly divided into two groups (15 in each group), they were bleomycin group and control group.①The BLM group was intratracheally instilled with belomycin (5mg/kg);② NS group was intratracheally instilled with saline (5mg/kg).

目的 观察肺纤维化鼠肺组织信号转导和转录活化因子1(STAT1)和血小板源性生长因子表达的变化,探讨其在肺纤维化的作用机制方法 30只Wistar大鼠随机分博莱霉素组和对照组,①BLM组:气管内灌注BLM(5mg/kg)诱导肺纤维化;②NS组:气管内灌注NS。

Methods Thirty Wistar rats were randomly divided into two groups (15 in each group), they were bleomycin group and control group.①The BLM group was intratracheally instilled with belomycin (5mg/kg);② NS group was intratracheally instilled with saline (5mg/kg).

30只Wistar大鼠随机分为博莱霉素组和对照组,①BLM组:气管内灌注BLM(5mg/kg)诱导肺纤维化;②NS组:气管内灌注NS。

Finally, we established rat model of PF induced by bleomycetin, and observed the interventional action of phenol total base to model. The analysis of experimental result including pathematologic and tissue biochemical indicator showed phenol total base of plumula nelumbinis have some therapeutic action to rat model of PF induced by BLM.

通过病理学观测及组织生化指标的检测(SOD、MAD、GSH一PX、Hyp),说明莲子心酚性总碱对博莱霉素致大鼠肺纤维化有一定治疗作用,可能的作用机制:降低肺纤维时胶原含量;抑制肺成纤维细胞的增殖;抗自由基和抗脂质过氧化作用及提高了机体内GSH一Px含量。

Each case was studied by CT scan at 1, 3, 6 and 12 months after the procedure. Results DSA features of all 9 cases were the same as those of enhanced CT/MRI scan. Lipiodol aggraded in the foci dispersedly.

栓塞后4天开始行经皮经肝瘤体内穿刺多点注射博莱霉素8~16mg ,间隔3~4天再次注射,连续2~3次,1月后复查 CT ,以后3、6个月及1年不定期复查 CT 。

Objective: To observe the effects of some cations and their chelating agents on lymphocyte SCE treated by bleomycin.

目的 观察几种离子和离子络合剂对博莱霉素作用淋巴细胞SCE的影响。

Make a copyof rat pulmonary fibrosis by infusing bleomycin through trachea , isolate and the pulmonary fibroblast, then interfered by atorvastatin ,divided into 3 groups of vacant ,TGF-β1 induced and atorvastatin interceped of different dosage , observe the structure of the cell by fiberscope ,the multiplication of the cell by MTT counting method, the expression of theα-SMA by immunity tissue chemistry staining method .

气管内注入博莱霉素(bleomycin,BLM)复制大鼠肺纤维化模型,并分离培养肺成纤维细胞,用阿托伐他汀对其进行干预,分为空白组、TGF-β1诱导组和不同剂量阿托伐他汀阻断组,用倒置纤维镜观察细胞的形态结构,MTT计数法观察各组细胞的增殖情况,免疫组化染色法定性观察α-平滑肌肌动蛋白(α-smooth muscleactin ,α-SMA)的表达情况。

Generally, you can camp free on any BLM land, unless it's specifically forbidden in an area.

一般来说,你可以自由在任何阵营博莱霉素的土地,除非它明确禁止的地区。

The relationship between CH4 production and input COD load in the NBLM and BLM was further analyzed statistically.

关系甲烷的生产和投入, COD负荷在nblm和博莱霉素是进一步统计分析。

From day 151 onwards, the CH4 concentrations in the NBLM and BLM were below detection limit.

从第一天151起,将甲烷浓度在nblm和博莱霉素均低于检出限。

Conclusions(1) BLM induced the morphological changes and reduction of cell viability in BECs.

2博莱霉素可诱导气道上皮细胞NF-κB信号的活化。

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