单核细胞的

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

In fact, rechallenge of T cells with CB CD34+ cells, or immature monocyte-derived dendritic cells in secondary MLC induced potent T cell proliferative responses.

事实上，再次激活的T细胞与脐带血CD34+细胞，或不成熟的单核细胞来源的树突状细胞在次级混合淋巴细胞培养下可以诱导有潜能的T细胞增殖反应。

Methods: Serum sICAM-1, IL-15 and monocyte ADCC of 66 Spleen-Deficiency patients were determined by enzyme-linked immunosorbent assay and modified thiazole blue test.

采用酶联免疫吸附法和改良噻唑蓝法对66例脾虚患者血清sICAM-1和白细胞介素-15(IL-15)及单核细胞抗体依赖性细胞介导的细胞毒反应进行检测。

We can observe five type blood cells including red blood cells, lymphocyte monocyte , neutrophil and thrombocyte through the microscope.

结果发现在鲫鱼外周血中可看到红细胞、淋巴细胞、嗜中性粒细胞、单核细胞和血栓细胞，未发现嗜酸性细胞和嗜碱性粒细胞，描述了上述各种血细胞在光镜下的形态和显微结构。

Aside from pancreatic enzymes activiation and autodigestive process, recent investigations have established that the upregulation of inflammatory mediator are believed to be the critical steps in the progression of mild pancreatitis to severe pancreatitis. Tumor necrosis factor-, ThyomboxaneA2 ,ProstaglandinsI2 are all important inflammatory mediator. TNF-( is one of cytokines. It is important to the over-production of ICAM-1,VCAM-1, TXA2 andPGI2. The ICAM-1 and VCAM-1 mediate both leukocytes adhesion and migration through the endothelium into tissues to connect with injuried target cells. The TXA2 and PGI2 are the production of arachidonic acid. They are responsible for the tissue ischaemia.

肿瘤坏死因子（Tumor necrosis factor-， TNF-、血栓素A2（ThyomboxaneA2，TXA2），前列环素（ProstaglandinsI2，PGI2）均是炎症反应中重要的炎性介质，其中肿瘤坏死因子-是非常重要的细胞因子之一，它由活化的单核细胞产生，在细胞间黏附分子（Intercellular adhesion molecule-1，ICAM-1）及血管细胞黏附分子(Vascular cell adhesion molecule-1，VCAM-1的表达、血栓素A2及前列环素过量生成方面起着重要的作用，前两者是介导白细胞与内皮细胞黏附，迁移于组织并与受损的靶细胞相结合的主要媒介，是炎症反应中的重要介质，后两者是花生四烯酸的代谢产物，亦是重要的炎性介质，参与构成血液循环障碍。

Results:The tumor was divided into two histologic subtypes:biphasic type(4 cases) and monophasic type(1 case).

结果 ：组织学检查分为双相性SRCC 4例，由癌和肉瘤样成分组成；单相性 1例，由差分化的肉瘤样梭形细胞、单核细胞与破骨细胞样多核巨细胞组成。

Methods Applying 1,25-_2D_3 induced osteoclast-like multinucleated cells and isolated mature rabbit osteoclasts cocultured with bone slices, the effects of icariin on the differentiation and bone resorbing activity of osteoclasts were investigated.

方法采用1，25-2D3诱导兔骨髓单核细胞形成破骨细胞样细胞以及原代分离的乳兔成熟破骨细胞与骨片共培养的方法，考察淫羊藿苷对破骨细胞的分化及骨吸收功能的影响。

Objective To investigate whether uninduced autologous bone-marrow mononuclear cell could survive and differentiate into myocardial cells and endothelial cells in the infarcted heart.

文章摘要：目的探讨未经诱导的自体骨髓单核细胞可否在梗死心肌环境中存活并分化为心肌细胞及血管内皮细胞。

Essel formation in itro was inhibited with mAbs against TNF-alpha, which, when secreted by cocultures of melanoma cells with human monocytes, induced endothelial cells under collagen gels to form branching, tubular structures.

在体外，TNF-alpha单抗能抑制血管形成，而当肿瘤细胞与单核细胞共培养时能分泌TNF-alpha，使胶原下的内皮细胞形成分枝和管状结构。

We also evaluated the expression of TIM-3 in CD4+T cells,monocytes and dendritic cells in peripheral blood of ITP patients.

同时，我们分析了ITP患者外周血CD4+T细胞，单核细胞和树突状细胞中TIM-3的表达变化。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新