单核细胞的

LRs were found in the surface of leukomonocyte, leukocyte and mononuclear phagocyte containing megalophage and DCs to different degrees.

oll样受体不同程度的表达于淋巴细胞、白细胞以及包括巨噬细胞和树突状细胞在内的单核吞噬细胞表面。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果：1、通过不同感染途径的实验证实，滴鼻感染的小鼠主要表现为间质性肺炎，而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现，随着感染Q热立克次体剂量的加大，动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现，在腹腔注射后第2d的脾和肝脏即可发现病原体，主要脏器的病理变化从第2d到第12d逐渐加重，第7d动物的病变最典型，至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统，在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内，呈多形性，多见圆形和杆状，大小不一。

Methods and Results—Human CD34＋primitive progenitors and CD14＋monocytic progenitors were injected locally into the ischemic limbs of diabetic mice.

方法和结果：人类原始CD34+祖细胞和CD14+单核祖细胞，通过局部注射到糖尿病小鼠缺血的四肢。

CD40/CD40L interactions were also shown to play a significant role in the maintenance of autoimmunity,High-level expression of CD40L and CD40have been detected on monocytes/macrophages from patients with active sgstemic lupus erythematosus,rheumatoid arthritis and other autoimmune diseases,indicating that the expression of CD40/CD40L on monocytes/macrophages could account for the formation of synovitis and osteoclasia.

CD40/CD40L是免疫细胞间的重要信号转导途径，单核巨噬细胞表达CD40与CD40L，分泌许多促炎性因子，参与类风湿关节炎滑膜炎形成、骨和软骨破坏。在系统性红斑狼疮、类风湿关节炎和其他自身免疫病中已检测出高水平表达的CD40与CD40L。

Outside the cells, it moonlights as autocrine mobility factor involved in cancer metastasis, neurolukin supporting the survival of specific neurons, and maturation factor mediating the differentiation of myeloid leukemic HL-60 cells to terminal monocytic cells.

在细胞外，PGI是一种肿瘤自泌移动因子和肿瘤转移有关，也是一种神经白介素和促分化成熟介子，分别具有支持脊髓及感觉神经元存活的能力和诱导白血病细胞HL-60成为单核白血球。

Objective To explore the application of human blood monocyte strain (THP-1 cells) with properties of pulmonary alveolar macrophage in study on pathogenesis of silicosis in vitro.

目的 探索具有肺泡巨噬细胞特性的人血单核细胞株（THP-1细胞）在矽肺发生机制体外研究中的应用。

LDL was cocultured with human THP-1 monocytes and endothelial cells separately for different times and LDL oxidation levels were examined.

将LDL与人单核细胞系THP-1和内皮细胞ECV304分别温育不同时间，检测LDL的氧化情况，研究不同时间对细胞氧化LDL的影响。

Prove that the soap glucoside of ginsengs is a kind of very good immunity strengthens the pharmaceutical through animals experiment, It is strengthening the systematic function of single-nuclear macrophage cell, promotes the formulation antibody and lymphocyte transformed, Promote some lymph secretion of factor, play a regulating role in natural killer cell-interferon-IL-2 regulate network, and protect the organization cell attacked by the virus.

通过动物实验证明人参皂甙是一种很好的免疫增强剂，它具有扶正固本、增强单核巨噬细胞系统功能，促进特异性抗体的生成和淋巴细胞转化，促进某些淋巴因子的分泌，对天然杀伤细胞-干扰素-白介素-2调节网起正调节作用，并能保护受病毒侵袭的组织细胞。

Flow cytometry of digested infarcts detected MPO in neutrophils and monocytes/macrophages.

对消化的梗死组织以流式细胞仪检测中性粒细胞和单核/巨噬细胞中的MPO。

Objective To study the effects of CD8+ T lymphocytes on processing macrophages of patients with asthma.

目的：探讨支气管哮喘患者CD8+T细胞对单核/巨噬细胞抗原递呈功能的影响。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新