单核细胞的

Check of lens of examination of printing of 1) constituent pressing can be in the afterbirth oar of big monocyte the appearance of " brooch " of the blue that finds bunch bacterium.

1组织压印片检查镜检可在大单核细胞的胞浆中找到成簇的蓝色的"别针"样菌。

Objective:To measure the proportion of monocyte-macrophage(CD64~+)in AA patient s bone marrow,the expression of RCAS1 mRNA in bong marrow mononuclear cells,and the influence of RCAS1 to colony forming unit-erythrocyte,colony forming unit-common precursor of granulocyte and macrophage;evaluate the monocyte-macrophage(CD64+),RCAS1 and their influence to the hematogenesis;explore the role of MPS in the pathogenesis of AA.

中文摘要：目的：测定再生障碍性贫血患者骨髓中单核—巨噬(CD64~+)细胞的比例，骨髓单个核细胞RCAS1 mRNA的表达水平以及RCAS1对红系形成集落、粒-单形成集落的抑制程度，评价单核—巨噬(CD64~+)细胞及其分泌的RCAS1对造血功能的影响，探讨单核-吞噬细胞系统在AA发病机制中的作用。

No primitive blood cells were observed in liver, which implies that the liver was not the hemopoietic organ in C. mydas. The development of erythrocytes includes 5 stages: primitive, early, middle, late, and mature. The body sizes of these cells increased first, then decreased, and increased in the end. The development of granulocytes includes 5 stages also: myeloblast, promyelocyte, meddle immature granulocytes, late immature granulocytes, and mature granulocytes. The body sizes of them decreased; and the sublobe of the nuclear may indicate the aging.

红血细胞的发育经历了5个阶段：原红血细胞、早幼红血细胞、中幼红细胞、晚幼红血细胞和红血细胞等阶段，其胞体体积经历了由小到大，由大到小、再到大的发育过程；粒细胞的发育经历了5个阶段：原粒细胞、早幼粒细胞、中幼白细胞、晚幼白血细胞和白细胞等阶段，胞体体积均由大到小变化，核分叶可能是粒细胞的衰老的标志；淋巴细胞和单核细胞的发育各经历了3个阶段。

Objective To study the mechanism of monocyte recruitment in atherogenesis and to clarify the effect of monocyte chemotactic protein-1 (MCP-1) in this process.

目的 了解动脉粥样硬化发病过程中单核细胞粘附并进入动脉内膜的机制，分析单核细胞趋化蛋白-1（MCP-1）基因表达对单核细胞粘附动脉内膜的作用。

Methods and Results-Here, we show that chemokine-mediated signals critically determine the frequency of monocytes in the blood and bone marrow under both noninflammatory and atherosclerotic conditions.

方法和结果：我们显示，在炎症和动脉硬化条件下的血和骨髓中，趋化因子介导的信号能精密的确定单核细胞的频率。

Results The level of antibodies against monocytes (34.94%) were higher than that of the antibodies against lymphocytes (26.67%) in pretransplant patients. The level of antibodies in first time transplant patients (32.5%) was lower than that of antibodies in retransplant patients (59.7%). The patients with intensity of antibodies against monocytes PRA more than ≥50% only accounted for 1.87%, 10%＜ MPRA ＜50% for 17.62% and MPRA ＜10% 15.44%,respectively.

结果 肾移植术前患者的抗单核细胞抗体水平较抗淋巴细胞抗体水平高，其百分比分别为34.94%和26.67%；而从患者初次和再次肾移植前的比较中可见，初次比再次产生的抗单核细胞抗体水平要低，其百分比分别为32.05%和59.7%；对于抗单核细胞抗体群体反应性抗体的强度，MPRA≥50%的只占1.87%，而50%＜MPRA＞10%以及MPRA＜10%的分别占17.62%和15.44%。

When HIV-1 in culture medium was exposed to a range of concentrations of urokinase, a dose-dependent inhibition of infectivity was observed in a variety of lymphoma and leukemia cell lines including MT4, CEM, H9, and peripheral blood mononuclear cells using assays for reverse transcriptase, P24 antigen and syncytia formation.

通过检测逆转录酶活力，P24抗原的表达和合胞体形成情况发现尿激酶可以抑制人体免疫缺损病毒对多种淋巴瘤和白血病细胞系，如MT4、CEM、H9和外周血单核细胞的侵染能力，并且这种抑制与尿激酶浓度呈剂量依赖关系。

These results indiacated that tranferring macrophages combinedwith cytokines could be a new adoptive immunotherapy protocol foradvanced cancer,and rTNF used in vivo locally could induce andactivate macrophages to kill tumor cells.Monocytes when activatedunderwent a series of phenotypic and functional changes includingthe expression of IL-2R which may provide an important immunoregu-latory pathway.The presence of lectin-like molecules on thesurface of monocytes and tumor cells may bring theeffector/target cells together,thus facilitating the inductionof apoptosis in target cells by triggering the production ofcytolytic factors and the modification of target of targer cell surface anti-gens.(such as HLA-DR).

综合以上结果可以得出以下结论：转输巨噬细胞并结合细胞因子的联合应用是肿瘤继承性免疫中的又一新的、有潜力的方法；抗肿瘤细胞因子rTNF可通过激活巨噬细胞在体内抑制对其不敏感的肿瘤细胞的生长；人单核细胞在一定条件下激活后，可表达IL-2R，进而一方面增强其自身对IL-2的敏感性，另一方面在体内也具有调节T细胞功能的作用；单核细胞和肿瘤细胞上存在的凝集素类受体可促使两种细胞之间在凝集素介导下相互接近，并诱发单核细胞产生细胞毒因子，以及通过调节靶细胞上表面抗原的表达，促进诱导靶细胞的细胞凋亡。

D. The function of stimulating xenogenous lymphocyte proliferation was the same between peripheral DCs and ascites PCs. E. The percentage of CD3〓CD56〓 cells was the same in CIK cells co-culture with DCs transfected with SKOV3 RNA, CIK cells co-culture with DCs, and CIK cells. F. The expansion rate of CIK cells can be accelerated by co-culturing with loaded or unloaded DCs. However, the expansion rate between loaded or unloaded group is the same. F. The strongest cytotoxicity against SKOV3 cell line was achieved by CIK cells co-cultured with DCs loaded with SKOV3 lysate.

结果：1、腹水可获得0.83±0.24×10〓个AMC/ml，单核细胞有0.74±0.25×10〓个/ml；2、卵巢癌患者外周血可获得0.87±0.20×10〓个AMC/ml，单核细胞有0.92±0.17×10〓个/ml；3、除CD86外周血单核细胞来源DC表达较高以外，其他表面分子在不同来源DC间没有统计学差异；4、不同来源DC的异基因刺激能力没有差异；5、与负载或未负载卵巢癌抗原的DC共培养并不能提高CIK细胞群中CD3〓CD56〓细胞的数量；6、CIK细胞增殖显著，培养14天时可扩增19.18±4.70倍，培养21天时可扩增35.82±4.36倍；7、与未负载或负载DC共培养的CIK细胞在培养第14天后增殖速率大于单纯CIK细胞。

It is unclear that how A20 is ex- pressed in patients of CHD, T2DM and CHD with T2DM.Inflammatory cytokines secreted from actived monocytes/macrophages in instable plaque result in plaque rupture, and those mono- cytes/ma- crophages come from circulation.

不稳定斑块中激活的单核巨噬细胞分泌大量的炎症因子导致斑块破裂，斑块中的单核巨噬细胞主要来自血液循环，故循环中的单核细胞可反映斑块中单核细胞状态。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新