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Methods Femoral arteries isolated from the rabbits which had been fed with a high cholesterol diet and locally perfused with MM-LDL within the artery beforehand, were used as the models. Antisense MCP-1cDNA was transferred into the arterial wall by injecting recombinant LNCX-anti-MCP-1/liposomal complex in the femoral sheath and the periarterial tissue.

以实验性高脂血及轻度氧化LDL局部保留灌注的家兔股动脉为模型,采用DOTAP阳离子脂质体包裹LNCX-anti-MCP-1质粒,将反义MCP-1 cDNA定位导入家兔股动脉鞘及周围组织,以原位杂交、 Northern杂交及狭缝杂交法观察反义MCP-1基因的表达,应用扫描电镜观察单核细胞在动脉内膜粘附的情况。

The membrane lipid fluidity of infected cells appeared obviously low-There were significant differences statistically(p.05-0.01)(2)By cytohisto-chemical stain-ing and microspectrophotometer quantitating,before cultured 72 hours,ACP and SDH in infectedcells raised.

动态观察1、6、24、72h培养后的淋巴细胞、单核细胞、中性粒细胞,发现感染后细胞膜脂的流动性明显降低,并随培养时间的延长而明显,和正常对照组比较有显著性差异(P<0.05~0.01)。

Understand leukocytes, their shapes, classifications, functions of neutrophils, monocytes, lymphocytes, eosinophils and basophils.

了解白细胞的形态和分类,粒细胞的功能,单核细胞和淋巴细胞的功能。

Moreover, in order to make clear whether IV infection touches off the cause and its pathogenesis of artherosclerosis inflammatory reaction. The study also uses IV of type A1 and A3 to infect repeatedly Jimpy mice with E gene defect, to observe AS histology change of Jimpy mice aorta and detect the change of IV antibody and inflammatory reaction medium (eg.TNF-α, IL-1) in Jimpy mice serum and express of monocyte chemotactic factor( MCF-1) and nuclear factor kB in Jimpy mice aorta tissue .

另外,为了弄清流感病毒感染是否是触发动脉粥样硬化炎症反应的发生原因及其机理,本研究还用A1、A3型流感病毒反复感染载脂蛋白E基因缺陷小鼠,观察小鼠主动脉的动脉粥样硬化组织学改变,并检测小鼠血清中流感病毒抗体、炎症反应介质(如TNF-a、IL-1等)变化情况以及小鼠主动脉组织中的单核细胞趋化因子-1(MCP-1)和核转录因子kB表达情况。

Objectives:To explore the effect of Shahepatide,an a ctive polypeptide extracted from shark liver,on secretion of IFN-γ and TNP-β from human periperal blood mononuclear cellsand to explore its liver-pr otective effect in mice with immune liver injury.

目的:探讨从海洋生物鲨鱼肝纯化获得的一种活性多肽对人外周血单核细胞分泌IFN-γ及TNF-β的影响,以及对小鼠免疫性肝损伤的保护作用。

Itric oxide inhibits the expression of adhesion molecules, and thus inhibits the expression of monocycles and platelet.

O还能抑制黏附分子的表达,进而抑制单核细胞、血小板的表达及内皮素-1的产生。

The individuals carrying the IL1RN*2 allele have a lower circulating level of IL-1ra in response to inflammation thereby inducing an increased activity of IL-1 which could be responsible for trigging the development of clinical manifestation in IgA nephropathy and Henoch-Schonlein nephritis.

为了进一步揭示IL-1ra基因多态性与其表型之间联系的本质,在本研究中我们对IL-1ra不同基因型IgAN和HSPN患者外周血单核细胞在炎症因子刺激下IL-1ra的产生能力进行了研究,以期阐明IL-1ra基因多态性对其功能的影响。

In the present study we describe a novel strategy for the development of mature DCs from monocytes within only 48 h of in vitro culture.

在本研究中,我们描述一个新的发展战略的成熟DCs由单核细胞内只有48个小时的体外培养。

The researchers now want to find out if there are other conditions where spleen-based monocytes are critical.

目前研究者们想弄清楚,基于脾脏的单核细胞是否在其它的情况也很重要。最后,器官中的罗德尼。

Chronic fatigue syndrome is most commonly triggered by an acute illness, like glandular fever, and it is the severity of this illness that decides whether you will develop the syndrome, the research found.

研究发现,慢性疲劳综合症最常见的触发因素是像传染性单核细胞增多症等的急性病,这种急症的严重性决定了人们是否会患上慢性疲劳综合症。

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