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单核细胞

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Megaspore mother cell just enters leptotene as The meiosis of microspore mother cell develop into tetrads . The meiosis of megaspore mother cell develop into pachytene while that of microspores develop into a single nuclear adjacent to cell wall.

当白杨小孢子母细胞减数分裂至四分体时,大孢子母细胞开始进入减数分裂细线期;而当小孢子发育至单核靠边期上时,大孢子母细胞减数分裂达到粗线期。

FUNGI Fungi are almost entirely multicellular, heterotrophic (deriving their energy from another organism, whether alive or dead), and usually having some cells with two nuclei multinucleate, as opposed to the more common one, or uninucleate per cell.

FUNGI Fungi是几乎完全地多细胞性,异养(获得他们的能量从另一个有机体,是否活或死)和通常有与二个中坚力量的有些细胞多核,与更加共同一个相对或者单核每个细胞。

The results showed that the tapetum of Zhenshan 97B disrupted promptly at the late uninucleate pollen stage. Whereas, the tapetum of Zhenshan 97A disaggregated at the pollen mother cell stage, the nuclear membrane and the cell membrane disaggregated, the phenomena continued to the binucleate pollen stage.

研究发现保持系绒毡层细胞在单核花粉晚期才开始迅速解体,而不育系绒毡层细胞在花粉母细胞时期就开始出现核膜、细胞膜解体,此过程持续到二核花粉时期。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果:1、通过不同感染途径的实验证实,滴鼻感染的小鼠主要表现为间质性肺炎,而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现,随着感染Q热立克次体剂量的加大,动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现,在腹腔注射后第2d的脾和肝脏即可发现病原体,主要脏器的病理变化从第2d到第12d逐渐加重,第7d动物的病变最典型,至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统,在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内,呈多形性,多见圆形和杆状,大小不一。

Results The main pathologic changes of high dosage group were inflammatory cell infiltration into the tissues around injecting location, subarachnoid space, and ependyma.

高剂量组动物脑组织主要病理改变为给药部位周围脑组织、蛛网膜下腔、室管膜的炎细胞浸润,炎细胞主要以胶质细胞、单核、淋巴细胞为主,没有脑组织的变性坏死。

The acute toxicity andmain organs of pathological section for 30 days were observed. Result 1. Ganoderma lucidum spores oil at 0.20g/kg, 0.40g/kg, 1.20g/kg dose couldsignificantly promote the lymphocyte transformation, raise clearance index numberand phagocytic index number, enhance the activity of NK cells and the level of TNF-α, IL-2 in spleen. Ganoderma lucidum spores oil at high dose and middle dose couldsignificantly enhance the serum erythrocytolysin level.

实验结果 1低、中、高灵芝孢子油组(0.20g/kg,0.40g/kg,1.20g/kg)均可提高小鼠单核-巨噬细胞的吞噬指数及碳廓清指数,促进ConA诱发脾淋巴细胞转化,增强小鼠NK细胞活性,提高脾细胞产生TNF-α和IL-2的能力;高、中剂量灵芝孢子油可提高小鼠的血清溶血素水平。

Most of the studies have demonstr ated that glutamine serves metabolic roles for macrophage.By glutamiolysis pat hway,glutamine provides ATP for the cellular metabolism,intermediates for the biosyn thesis of parine,pyrimidine and nuclecotides,and nitrogen for the formation of glucosamine,GTP and NAD+.

研究表明谷氨酰胺是单核巨噬细胞主要的代谢底物,通过谷氨酰胺酵解途径,为细胞代谢提供能量;为细胞合成DNA和mRNA提供嘌呤、嘧啶、核苷酸生物合成前体;提供氨基葡萄糖,GTP和NAD+合成的氮前体。

Results While the ES lumen and perisaccular region were infiltrated with mononeuclear-phagocyte at the 3rd day post-vaccination, plasmocyte and lymphatic cells become the predominant infiltrating cells in the ES at the 7th day. The KLH in the ES lumen were phagocytized at the 3-7th day post-vaccination. S-phase cells and IgG positive cells in ES increased markedly in the 3rd day and 7-14 days post-vaccination respectively with similar localization.

结果 内耳受抗原刺激后3 d内淋巴囊囊腔和囊周区域出现单核吞噬细胞浸润,7 d内淋巴囊的浆细胞和淋巴细胞大量增加;3~7 d内淋巴囊囊腔KLH被吞噬,同时S期细胞和IgG阳性细胞逐渐增多,二者的出现部位相似。

Results While the ES lumen and perisaccular region were infiltrated with mononeuclear-phagocyte at the 3rd day post-vaccination, plasmocyte and lymphatic cells become the predominant infiltrating cells in the ES at the 7th day. The KLH in the ES lumen were phagocytized at the 3-7th day post-vaccination.

结果 内耳受抗原刺激后3 d内淋巴囊囊腔和囊周区域出现单核吞噬细胞浸润,7 d内淋巴囊的浆细胞和淋巴细胞大量增加;3~7 d内淋巴囊囊腔KLH被吞噬,同时S期细胞和IgG阳性细胞逐渐增多,二者的出现部位相似。

Among its many biological activities, the major function of GM-CSF is to stimulate hematogenie stem cells prolification from silent stage to S phage, so that the stem cells can differentiate into granulocyte-macrophage cells.

有4个外显子和3个内含子,基因定位于5号染色体长臂5q21-5q32区,大多数器官均能产生GM-CSF,GM-CSF有多种生物活性,作用于多种细胞谱系,其主要作用是刺激造血祖细胞增殖即从静止期进入S期,并分化为粒细胞---单核巨噬细胞。

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