单核细胞

And Spatholobus suberectus Dunn. provided protection activities against decapsulted KP-induced ER stress in U937 monocytes、B lymphoblast CA46 cells and PBMC of normal individuals. We also found a significantly increase of IL-1β、IL-6 and TNF-α proinflammatory cytokine by PBMC obtained from normal individual under decapsulated KP treatment.

我们筛选超过60种中药及生物活性成分中，并且发现小蘗碱、牛磺酸、鸡血藤萃取物和穿心莲萃取物能够保护去荚膜克雷伯氏肺炎杆菌诱发U937单核球细胞、CA46 B淋巴球细胞和健康者身上周边血液单核球细胞的内质网压力。

RESULTS: Pseudopodia of mononuclear macrophage in the normal control group were intact, nuclear membrane was normal, and nucleoplasm was uniformed.

结果：正常对照组单核巨噬细胞伪足完整、核膜正常、核质均匀；20，100，200 mg/L纳米羟基磷灰石诱导24 h后，单核巨噬细胞具有典型的凋亡形态学特征。

The observation showed that sterile plants and fertile plants in the pollen mother cell stage is not very different, when microspore mother cells of male sterile plants enter meiosis period, it could form normal tetrad cell , tetrad cell is normal in early development stage, In the uninucleate microspore stage , tapetal cells were vacuolization, the microspores were extruded to the middle by tapetal cells.

本研究利用石蜡切片法，结合光学显微镜技术对樱桃萝卜核质互作雄性不育系的不育株和对应保持系可育株的花药发育过程进行细胞形态学观察，观察结果表明：不育株与可育株在花粉母细胞时期差别不大，不育株的花药小孢子母细胞进入减数分裂期后，可以正常的形成四分体，四分体前期发育正常，而在单核小孢子期绒毡层细胞出现液泡化，绒毡层细胞向中间挤压小孢子。

The reproductive development process of birch was described as follows: Male inflorescences extended from apical bud in early June. In later June, stamen primodium was differentiated in the bract of male inflorescence and the differentiation of bract was generated in female inflorescence. During July, anther layers and archesporial cell were differentiated in anther, then archesporial cell developed into mother microspore cell. Pistil primodium came into being at the same time. In early part of August the meiosis of mother microspore cell started. In later August, mono-nucleus microspore was formed. After September, both male inflorescence and female inflorescence were dormant.

白桦的生殖生长发育过程如下：6月初，雄花序从顶芽中生长出来。6月中下旬，雄花序苞片上分化出雄蕊原基，雌花序分化出苞片。7月，雄花花药分化出花药壁和孢原细胞，孢原细胞演化为小孢子母细胞，雌花序苞腋处分化出雌蕊原基；8月中上旬，小孢子母细胞减数分裂，8月下旬形成单核小孢子；9月后雄花序以单核小孢子状念越冬，雌花序以雌蕊原基状念越冬。

Results: Tyroserleutide can significantly increase the life span of H22 tumor-bearing mice by 50-70% in dosages of 20ug/kg/d-80ug/kg/d,specially the high dosage of 80ug/ml can significantly increase the life span by 69.24%; Tyroserleutide can inhibit the growth of transplanted hepatocellular tumor BEL-7402 in nude mice,the rate of tumor inhibition was25-50% in dosages of 40-320ug/ml ,the inhibition rate of 160ng/ml was 44.03%; Tyroserleutide could inhibit the growth of H22 and BEL-7402 tumor in a dose-dependent manner. Simultaneously, tumoricidal activity of tyroserleutide against BEL-7402 cell line in vitro was observed hinger when compared with the control group(P.05).The inhibition effect of 72hrs was higher than 24hrs,48hrs,96hrs.And specially the high dosage of 160ug/ml can significantly inhibit growth of tumor cell by 19.36%. Tyroserleutide can activated PEM and marked enhance cytotoxicity andphagocytosis functions in vitro and in vivo. The OD values of cytotoxicity were observed hinger when compared with the control group(P.05).The cytotoxicity of macrophages activated by tyroserleutide against BEL-7402 and B16-F10 was 35.58%,61.2% in vitro and21.39%,47.63% in vivo. The cytotoxicity rate of nude mice PEM was 32.86%,73.07% in vivo. Furthermore, tyroserleutide alone could stimulated the production of IL-1B TNF- a and NO by M . Tyroserleutide and LPS could synergistically activated M producing more cytotoxicity effectors. Conclusion: Tyroserleutide had inhibition functions against hepatoma carcinoma .Its possible mechanisms were related to the affect that Tyroserleutide could inhibit tumor cell directively and induce tumor cells apoptosis or death effectively.

结果：酪丝亮肽能显著延长腹水型肝癌H_(22)小鼠的生存时间，给药剂量为80μg／kg／d时疗效最显著，达到69.24％，在20μg／kg／d-80μg／kg／d剂量范围内生命延长率为50-70％，给药剂量与荷瘤鼠生存时间呈现一定量效关系；酪丝亮肽能显著抑制人肝癌BEL-7402移植瘤裸鼠的肿瘤生长，给药剂量为160μg／kg／d时疗效最显著，抑制率为44.03％，并且在40-320μg／kg／d剂量范围内抑制率为25-50％，给药剂量与肿瘤抑制率呈现一定量效关系；酪丝亮肽体外对人肝癌BEL-7402细胞生长有一定的抑制作用，在作用72hrs时各浓度酪丝亮肽对肿瘤细胞的抑制作用较24hrs、48hrs、96hrs明显，其中浓度为100μg／ml时抑制率达19.36％；酪丝亮肽体内外均能增强小鼠腹腔巨噬细胞对肿瘤细胞的杀伤：体外作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与效应细胞对照组相比有显著性差异(P＜0.05)杀伤率分别达到35.58％、61.2％；体内作用中巨噬细胞对BEL-7402、B16-F10的杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P 。05)，杀伤率分别达到21.39%、47.63%；裸鼠腹腔巨噬细胞经酪丝亮肤作用后对BEL一7402、B 16一F10杀伤功能明显增强，与生理盐水对照组相比有显著性差异(P.05)，最高杀伤率分别达到32.86%、73.07%；酪丝亮肤能增强单核巨噬细胞系统的吞噬功能，吞噬指数与生理盐水组比较有显著性差异(P.05)；酪丝亮肤体外作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与效应细胞对照组相比有显著性差异(P.05)；酪丝亮肤体内作用能促进小鼠腹腔巨噬细胞分泌合成细胞毒效应分子IL一lp、TNF一Q和NO，与生理盐水对照组相比有显著性差异(P.05)；酪丝亮肤能促进鼠巨噬细胞株R戌W264.7分泌合成IL一1p和NO，IL一1日、NO水平分别在酪丝亮肤作用24hrs、12hrs时达到高峰，酪丝亮肤单独应用能提高巨噬细胞的分泌合成功能，而且酪丝亮肤能与LPS协同作用刺激巨噬细胞的细胞毒效应分子分泌合成。

Monocytic progenitors seem to be less affected by diabetes, but potential pro-angiogenic activities of freshly isolated monocytic progenitors remain unexplored.

单核系的祖细胞似乎受糖尿病的影响要小一些，但是新鲜分离出来的单核祖细胞潜在的血管生成活性尚无定论。

The results shows that the tapetal expanding abnormally occurs in dyadphase stage, microspore abortion occurs in the early of monokaryon stage, disaggregation in the end of monokaryon stage, only some spall of microspore is observed in monokaryon stage, the four cell walls also exist, the tapetal cells became completely vacuolated, almost filled the whole locule. vascular bundle of male sterile line anther vanish at mature pollen stage.

结果发现花药绒粘层在二分体时期发生异常，小孢子在单核前期开始败育，至单核后期完全解体，花药发育后期不育系药腔中只观察到少量的小孢子残体，花药壁的四层细胞依然存在，绒粘层细胞已经彻底液泡化，占据了药腔的整个空间，花粉成熟期不育系花药维管束消失。

The situation of abnormal development of male cells is as follows:microspore mother cell can't enter into meiosis because of intense vacuolation,shrink and disintegration of its cytoplasm;although vacuolated microspore mother cell can enter into meiosis,it can't form normal dyad and degenerate in the middle process;dyad and tetrad become vacuolated and can't develop normally;cytoplasm of microspore shrinks around the nucleus at the stage of central nucleus microspore,the shape of microspore is twisted into crescent or irregular shape,at last its cytoplasm and nucleus are disintegrated and crescent vacant microspore presents;nutritive substances can't be accumulated at the stage of vacuolated microspore,cytoplasm is disintegrated,and microspore turns into a big vacant pollen.

雄性细胞异常发育有几种情况：小孢子母细胞强烈液泡化，细胞质收缩解体，不能进入减数分裂；小孢子母细胞液泡化，虽能进入减数分裂，但不能形成正常二分体而中途退化；二分体、四分体细胞液泡化，不能进行正常发育；单核小孢子中央期，细胞质收缩包围核，小孢子形状扭曲呈月牙形或不规则形，最终细胞质和核解体而呈月牙形的空壳小孢子；单核液泡期的小孢子不能积聚营养物质，细胞质解体而成为大的空壳花粉粒。

Rheumatoid arthritis can affect any joint where cartilage overlies bone and with a joint cavity lined by synovial membrane that contains synovial fluid.

单核／巨噬细胞在类风湿关节炎的发病过程中起着重要的作用。单核／巨噬细胞不仅仅能够产生很多前炎症细胞因子和化学因子，而且它可通过很多机制引起类风湿关节炎的软骨和骨的损伤。

Experimental results show that there are existing some indifferent mechanisms to the pollen sterilization of the Ms types: during the period of single nucleic to three nucleic pollen cell,we observed that the cell of xylem and phloem in anther septum abnormally developed,also the cell in the sheath of vascular bundle,smaller and arranged irregularly; the metabolic block developed too,es...

结果表明，不育类型的花粉败育有着一些共同的机理：在花粉单核期至三核期可见到花药隔维管束的木质部及韧皮部细胞发育较差，维管束鞘细胞发育不良，体积较小，排列紊乱；在单核花粉期至三核花粉期均发生物质代谢障碍，特别在花药部位尤为明显；由于维管束发育不良和花药物质代谢障碍，导致了花粉缺乏营养而败育。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。