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To understand the mononuclear cells in such a state of gene expression, we use gene chip technology to investigate the differentiation of monocyte gene expression.

为了理解单核细胞在这种状态下的基因表现,我们运用基因芯片的技术来调查单核细胞的分化的基因表达。

Monocytic progenitors seem to be less affected by diabetes, but potential pro-angiogenic activities of freshly isolated monocytic progenitors remain unexplored.

单核系的祖细胞似乎受糖尿病的影响要小一些,但是新鲜分离出来的单核祖细胞潜在的血管生成活性尚无定论。

Objective The radiation sensitive gene rad 21 of Schizosaccharomyces pombe is involved in the repair of double-stranded breaks in DNA and is essential for mitotic growth. The hHR21 sp gene is its human homologue.

目的 检测UV和γ辐射对正常人外周血单核细胞的hHR2 1sp基因转录表达水平及hHR2 1sp在范可尼贫血骨髓造血细胞和激活后的外周血单核细胞的转录表达情况,并分析hHR2 1sp基因在FA贫血发病机制中的作用。

The situation of abnormal development of male cells is as follows:microspore mother cell can't enter into meiosis because of intense vacuolation,shrink and disintegration of its cytoplasm;although vacuolated microspore mother cell can enter into meiosis,it can't form normal dyad and degenerate in the middle process;dyad and tetrad become vacuolated and can't develop normally;cytoplasm of microspore shrinks around the nucleus at the stage of central nucleus microspore,the shape of microspore is twisted into crescent or irregular shape,at last its cytoplasm and nucleus are disintegrated and crescent vacant microspore presents;nutritive substances can't be accumulated at the stage of vacuolated microspore,cytoplasm is disintegrated,and microspore turns into a big vacant pollen.

雄性细胞异常发育有几种情况:小孢子母细胞强烈液泡化,细胞质收缩解体,不能进入减数分裂;小孢子母细胞液泡化,虽能进入减数分裂,但不能形成正常二分体而中途退化;二分体、四分体细胞液泡化,不能进行正常发育;单核小孢子中央期,细胞质收缩包围核,小孢子形状扭曲呈月牙形或不规则形,最终细胞质和核解体而呈月牙形的空壳小孢子;单核液泡期的小孢子不能积聚营养物质,细胞质解体而成为大的空壳花粉粒。

Objevtive: To investigate the effect of effective parts of Zingiber officinal on the adhesion of ECV-304 cells with monocytes cultivated in vitro and on the expression of monocyte chemotactic protein-1 (MCP-1) and adhesion molecules.

中文摘要:目的:研究鲜姜有效部位对离体培养的血管内皮细胞与单核细胞的黏附力及对单核细胞趋化蛋白和黏附分子表达的影响,探讨其保护血管内皮细胞的作用机制。

Rheumatoid arthritis can affect any joint where cartilage overlies bone and with a joint cavity lined by synovial membrane that contains synovial fluid.

单核/巨噬细胞在类风湿关节炎的发病过程中起着重要的作用。单核/巨噬细胞不仅仅能够产生很多前炎症细胞因子和化学因子,而且它可通过很多机制引起类风湿关节炎的软骨和骨的损伤。

The histopathologic changes included lymphocyte and monocyte infiltration,hyperplasia of synovial cells and small vessels,interstitial fibrosis,hyaline degeneration and cartilaginous metaplasia.The immunohistochemical observations showed that the high expressions of IL-1 and IL-6 were significantly different between the pathologic plicae and the control groups(P<0.01).The positive expressions of IL-1 and IL-6 were the synovial cells and monocyt-lymph cells in the pathologic synovial plicae.The positive expressions of MMP-1 and TIMP-1 have significant difference between the experiment and control group(P<0.01,P<0.05).The expression of MMP-1 was positive in synovial lining cell,monocyte,fibroblast,endothelial cell in small vessel and chondrocyte.The TIMP-1 expression was detected in the synovial lining cells and a small quantity fibroblast.

结果 正常滑膜皱襞和病理性滑膜皱襞在滑膜细胞增生及小血管增生、间质纤维化及玻璃样变、软骨化生组织学改变方面,差异均有显著性(P<0.01);IL-1、IL-6在病理性滑膜皱襞内的增生滑膜细胞、单核及淋巴细胞和在正常滑膜皱襞内的表达差异均有显著性(P<0.01); MMP-1、TIMP-1在病理性滑膜皱襞和正常皱襞内的阳性表达,差异具有显著性(P<0.01,P<0.05),MMP-1在增生滑膜衬里层细胞、单核和纤维母细胞、血管内皮细胞和软骨化生的软骨细胞呈阳性表达;TIMP-1只在滑膜衬里层细胞和少量纤维母细胞有表达。

The model of ECV-304 cell oxidative stress injury was established by hydrogen peroxide (H2O2).Then EPZ-contained blood serum was taken as experimental drug. The adherence of monocytes to endothelial cell were measured by method of rose Bengal. The total RNA of cells was extracted. The intercellular adhesion molecule-1 (ICAM-1),vascular cell adhesion molecule-1 (VCAM-1) and MCP-1 mRNA expression in cells were detected by RT-PCR.MCP-1 protein expression were detected by ELISA.

采用过氧化氢建立离体培养的血管内皮细胞(ECV-304)氧化应激损伤模型,取健康大鼠每日灌服不同剂量的鲜姜有效部位(200,400,800 mg·kg-1)或阳性对照药洛伐他汀(40 mg·kg-1),取含药血清作为受试药物,用孟加拉玫红染色法测定单核细胞与内皮细胞的黏附力;逆转录聚合酶链反应测定细胞内细胞间黏附分子-1(ICAM-1)、血管细胞黏附分子(VCAM-1)以及单核细胞趋化蛋白(MCP-1)的mRNA表达水平;酶联免疫吸附法测定MCP-1蛋白表达水平。

Experimental results show that there are existing some indifferent mechanisms to the pollen sterilization of the Ms types: during the period of single nucleic to three nucleic pollen cell,we observed that the cell of xylem and phloem in anther septum abnormally developed,also the cell in the sheath of vascular bundle,smaller and arranged irregularly; the metabolic block developed too,es...

结果表明,不育类型的花粉败育有着一些共同的机理:在花粉单核期至三核期可见到花药隔维管束的木质部及韧皮部细胞发育较差,维管束鞘细胞发育不良,体积较小,排列紊乱;在单核花粉期至三核花粉期均发生物质代谢障碍,特别在花药部位尤为明显;由于维管束发育不良和花药物质代谢障碍,导致了花粉缺乏营养而败育。

BLyS mRNA expression in peripheral blood was measured by RFQ-PCR in 18 children with infectious mononucleosis and the results were compared with those measured in 15 healthy controls.

成功建立RFQ-PCR检测BLyS mRNA含量的方法,具有较好的检测灵敏度和重复性;而且发现BLyS在儿童传染性单核细胞增多症发病过程中可能起了重要作用,BLyS可以作为儿童传染性单核细胞增多症的一个参考指标。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。