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The results showed that the hereditary mode of handedness or preferential foot or hand-clasping is the dominant heredity of single gene of autosome,and the right type of all of them is the dominant character.

采用Slater区分单基因和多基因遗传的计算模式及Smith无偏分析方法对21个家系资料的分析表明:利手、优势足、扣手特征均为常染色体单基因显性遗传,R型为显性性状。

The results showed that the hereditary mode of rolling tongue or pointed tongue is the dominant heredity of single gene of autosome,and the positive type of them is the dominant character;Twisting tongue is the recessive heredity of single gene of autosome,while the positive type is the recessive character.

采用Penrose先证者同胞法和分离分析方法对72个家系资料的分析表明:卷舌、尖舌均为常染色体单基因显性遗传,阳性为显性性状;翻舌为常染色体单基因隐性遗传,阳性为隐性性状。

Three phenotypes:the homozygous line of resistance,heterozygosis line and homozygous line of sensitivity were exhibited in T2 generation.

试验结果显示,卡那霉素抗性和抗虫性状在转基因植株自交后代中的表现基本符合显性单基因的分离规律。

In order to reduce calculation error, the frequency distribution of average values is used to compute the mixed distribution's digital features of each component distribution, thereinto, the number of the component distribution is determined by AIC, choose the number that meets the minimum value of AIC as the component number of mixed distribution, and the other parameters are estimated by EM algorithm; Secondly, because each component distribution is corresponding to a kind of major gene genotype, according to the values of the average and variance of the each component distribution, we can use the limit error of the normal distribution to plot each individual into the correspondent component distribution, namely into correspondent major gene genotype. Then we regard each major gene genotype as a treatment level of one-way analysis of variances, and the one-way multivariate analysis of variance is carried out to calculate the covariance matrix of major gene effect, covariance matrix of polygene effect, covariance matrix of environment effect and so on; At last, combining the weights of the each component distribution of mixed distribution, we can calculate the variance of major gene effect, the variance of polygene effect, environmental variance and the genetic gain of the quantitative trait.

为减小计算误差,本研究采用均值的频数分布来计算各成分分布的数字特征,其中成分分布个数根据AIC准则,选择使AIC值达到最小的成分分布个数作为混合分布的成分分布数,分布中其它参数的确定利用EM算法来估计;其次,每个成分分布对应一种主基因基因型,根据各个成分分布的均值和方差,利用正态分布的极限误差将每个个体划分到相应的成分分布中,即相应的主基因基因型中,将每种主基因型作为单因素方差分析的一个处理水平,对其进行单因素的多元方差分析,分别计算主基因效应协方差阵、多基因效应协方差阵、环境协方差阵等参数;最后结合混合分布中各成分分布的权重即各主基因基因型的分离比例,计算主基因效应方差,多基因效应方差和环境方差,以及遗传力等参数,进而计算该数量性状的遗传进展。

Monogenic forms of hypertension are very rare, but have a well-characterized heredity.

单基因的高血压是非常罕见的,但有一个很好的遗传特征。

PCR-RFLP in FSHR gene 5'–flanking region with exon 1 digested by restriction endonuclease TaqⅠdemonstrated that the frequencies of allele A (0.5500) and genotype AA (0.5000) in twinning cows were higher than that of allele A (0.3500) and genotype AA (0.3000) in monovular cows for Qinchuan cattle, while The frequencies of allele B (0.5937) and genotype BB(0.6875) in twinning cows were higher than that of allele B (0.5416) and genotype BB (0.4167) in monovular cows for Holstein cattle. Key words: Bovine; Twinning; FSHR gene; PCR-RFLP

FSHR基因5'端(包括侧翼序列和第一外显子)的限制性内切酶TaqⅠ的PCR-RFLP标记研究发现,在秦川牛中双胎母牛的A基因频率(0.5500)和AA基因型频率(0.5000)分别高于单胎母牛的A基因频率(0.3500)和AA基因型频率(0.3000);在黑白花奶牛中双胎母牛的B基因频率(0.5937)和BB基因型频率(0.6875)均高于单胎母牛的B基因频率(0.5416)和BB基因型频率(0.4167),也就是FSHR基因的5'端的PCR-RFLP标记在一个品种内单胎母牛和双胎母牛之间有一定趋势,但两个品种的趋势不同。

The construction process includes the following steps: constructing recombinant plasmid containing phhA and phhB; transforming the recombinant plasmid to hygrophilous aeromonad; and screening recombinant hygrophilous aeromonad with the recombinant plasmid.

该重组菌中含有β-酮硫解酶基因phbA和乙酰乙酰辅酶A还原酶基因phbB。其构建方法包括以下步骤:1构建含phbA和phbB基因的重组质粒;2转化该重组质粒到嗜水气单胞菌中;3筛选出含有重组质粒的重组嗜水气单胞菌。

Monogene Ht1, Ht2, Ht3, and Ht were crossed with inbreds of same resistant level and different resistant level to study the monogenic effects and polygenic effects on spots number, size, spread speed, spore production and incubation period.

通过单基因Ht1、Ht2、Ht3、Ht,与同一水平抗性自交系以及与不同水平抗性自交系组配,研究单基因处于杂合状态时在控制病斑数量、面积、病斑扩展速度、产孢量和潜伏期等方面的单基因、多基因的联合效应。

The results showed that resistant gene Ht in F1 heterozygote was the most effective on controlling spots number and size; all monogene in heterozygote could produce spore by moisture culture and resistant gene Ht1 was the most effective; resistant gene Ht1 in medium level, Ht3 in high level, and Ht in low level of vertical resistance of heterozygote, were the most effective on controlling spots spread; while Ht2 in high level of vertical resistance of heterozygote was the most ineffective on controlling spots spread; and all resistant monogene in heterozygote showed superior to their parents on controlling incubation period and gene Ht was more significant than other genes.

结果表明,抗性单基因Ht处于F1代杂合状态时,控制病斑数和病斑面积的效应最强;单基因处于杂合状态时,湿培48h病斑全部能产生分生孢子,且处于同一水平抗性杂合状态时,Ht1控制产孢量的效应最强;Ht1处于中水平、Ht3处于高水平和Ht、处于低水平垂直抗性杂合状态下,控制病斑扩展效应最强;而Ht2处于高水平垂直抗性杂合状态下,控制病斑扩展效应最弱;抗性单基因处于杂合状态下,控制潜伏期多表现超亲现象,Ht控制病害潜伏期比其它单基因显著。

Among over 300 genodernatoses, causative genes have been identified in 170 monogenetic diseases, while gene mapping has been performed in over 100 monogenetic and polygenctic skin diseases.

目前因遗传导致的皮肤病有300多种,其中170多种单基因皮肤病已确定致病基因,近100多种单基因皮肤病和多基因皮肤病已经基因定位。

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