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In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文题名反义与反基因寡核苷酸及其萘二酰亚胺偶联物对靶基因表达的抑制作用研究副题名外文题名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 论文作者李军生导师张元兴魏东芝教授学科专业生物化工研究领域\研究方向生物化学与分子生物学学位级别博士学位授予单位华东理工大学学位授予日期2001 论文页码总数106页关键词基因表达基因治疗反义寡核苷酸反基因寡核苷酸核酸馆藏号BSLW /2001 /Q78 /264 针对人表皮癌抗阿霉素细胞株(KB-A-1)的多药抗药性问题,本文从反义核酸和反基因核酸角度,通过MTT法检测细胞生长情况,ELISA法检测基因表达产物P-gp表达水平的变化,对寡核苷酸抑制肿瘤细胞MDR1基因表达的机制进行了探讨。

Generally, most of the follicles undergo atresia during their development in mammals, and only a few grow to maturation and ovulation. For many years, the mechanisms of follicular atresia have been one of the foci of study. Recently, with the development in studies on cell apoptosis, it has been proved that follicular atresia is a process of cell apoptosis. However, the endocrinological and molecular evens underlying follicular development and atresia and granulosa cell apoptosis in the goat has not been studied.

中文题名山羊卵泡发育、闭锁及其调控机理的研究副题名外文题名 Studies on follicular development and atresia and their regulatory mechanism in goat 论文作者于元松导师谭景和教授学科专业基础兽医学研究领域\研究方向动物胚胎学与胚胎生物工程学位级别博士学位授予单位东北农业大学学位授予日期2002 论文页码总数71页关键词山羊卵泡发育馆藏号BSLW /2003 /S827 /3 哺乳动物卵泡在发育过程中绝大多数闭锁退化,只有少数卵泡发育成熟至排卵。

The conclusions are as follows:(1) Neologisms in each Huayu region can be classified into two major categories:self-originated and others-originated,among which the new-born words are "absolute new words" and the inherited word are "relative new words",and there are also others-originated elements in the morphemic and sense systems of new words;(2) Variation can be seen in the morpheme,formation,building and sense of new words in Huayu regions,besides individuals of new words;(3) Aggregation of current new words and compound words with one common morpheme and a same construction,together with the aggregation of synonyms and that of different senses in polysemies,reflect the relevance of the systems of new words in Huayu regions in their variation;(4) Regular participation of hinting sense of a formation element in forming and building new words is an important way of producing new sense of morpheme,and an important reason for the current emergence of words with more than one new senses;(5) Compared with ordinary words,the productivity of ways of word formation in forming new words both in general and of a particular class will change and new ways of word formation appear in Huayu regions;(6) The semantic collocation of the verbal morpheme of new verbs in a phrase has a great influence on the location of its structural center,and the complex syntactic behaviors of new verbs are related to the different processes of argument integration;(7) The processes of building new words with the same meaning differ in levels of approaches to motivation cognition,perspectives of motivation cognition,morpheme motivation and morpheme expression,etc.;(8) The lexical interaction in Huayu regions results in lexical subsystem intersections of current new words across two,three and four regions.

本文的主要结论是:(1)各华语区新词均可分为&自源新词&和&他源新词&两大类,其中的新生词和传承词分属&绝对新词&和&相对新词&,新词语的词素、词义系统中也含有他源成分;(2)除词语个体外,华语区新词在词素、构词、造词、词义等方面均体现了某种程度的变异:(3)通用词语聚合、同素同构词聚合、同义异形词聚合与一词多义聚合集中反映了各华语区新词语系统在变异中的关联;(4)构词单位经常提示词义参与构造新词是产生新语素义的重要途径,也是当代多新义词现象的重要成因;(5)相对于一般词语,构词方式在新词语中的总能产性和在某一词类中所体现的能产性都有所变化,华语区也产生了新的构词方式;(6)新动词的动素在短语中的语义搭配对结构核心的位置有很大影响,新动词的复杂句法表现与不同的论元整合过程有关;(7)同义新词造词过程的差异包括理据认知途径、理据认知角度、词素理据和词素表达等不同层面;(8)华语区的词汇互动形成了双区、三区和四区通用新词等词汇子系统交集,作为华语核心,普通话所含纳的通用词语多于各区域变体。

In this thesis, the basic principles of using boundary element method to extract capacitance and the multipole accelerated algorithm are introduced. A new conductor dividing and numbering method are realized. The realizing process of multipole accelerated algorithm, especially the realizing process of unit cube's capacitance extraction, is detailedly illuminated. The realizing program chart of multiconductor capacitance extraction is given.

在本论文中,介绍了应用边界元法提取电容的基本原理和多极加速算法的基本原理;实现了一种新的导体分割编号方法;对多极加速算法的实现过程,主要是单位立方体电容提取的实现过程作了详细地说明;给出了多导体电容提取的程序实现框图。

In order to study novel polyquinolines for their applications in the fields of electroluminescent devices and chemosensors, we synthesize polyquinolines containing phenylamine moiety for single-layer LEDs; moreover, we synthesize polyquinolines with different molecular structures to investigate their properties as fluorescent chemosensors.

中文题名聚喹啉的合成与表征副题名外文题名 Synthesis and characterization of novel polyquinolines 论文作者童辉导师王利祥学科专业高分子化学与物理研究领域\研究方向学位级别博士学位授予单位中国科学院长春应用化学研究所学位授予日期2002 论文页码总数152页关键词发光材料共轭聚合物荧光传感器电致发光聚合物聚喹啉馆藏号BSLW /2003 /O633 /17 本论文是以研究新型聚喹啉材料在电致发光和荧光传感器方面的应用为目的,将芳胺基元引入到聚喹啉主链上,以期使聚喹啉可用于单层电致发光器件中;同时通过合成不同分子结构的聚喹啉来考察其作为荧光传感器的性能和规律。

Was established in 2002, Main Sodium Sulfate, Soda, protopine, sodium hexametaphosphate, such as chemical raw materials, product sales a number of provinces and cities and more than date of production enterprises, sales of chemical raw materials and the direct provision of goods original units; in the market development has a strong strength.

沈阳沧连海商贸有限公司成立于2002年,主营元明粉,纯碱,片碱,六偏磷酸钠等化工原料,产品销售多个省市地区,并为多家日化生产企业,及化工原料销售单位直接提供货原;在市场开发方面有强的实力。

The corporation cooperates closely with universities and research institutions and spends millions of yuan every year improving the strains of mulberry and silkworms, researching and popularizing sericultural techniques and ways to prevent and cure diseases caused by pests, and solving technical problems arising in silk reeling.

集团公司与院校科研单位紧密合作,每年投入数百万元加强蚕桑品种改良;种养技术以及病虫防治的研究与推广;组织缫丝生产技术攻关,出口厂丝平均等级达3A+24,最高达6A;建设茧、丝、服装生产基地,依托基地扩大外贸出口。

Discussing and analyzing the case that Foxconn Tenology Group sued the two reporters belong to "China Business News", this article summarizes the thought-provoking points of the case: accuser suing the reporters individuals setting aside the newspaper, claiming the former astronomical compensation; court freezing the private assets.

这篇文章富士康诉《第一财经日报》记者案进行了多方面的讨论和分析,总结归纳了该案件的非同寻常之处所在:原告抛开新闻单位起诉记者;向身为工薪族的新闻从业者索赔达千万元;法院冻结记者个人资产。

An individual who embezzles less than 5,000 yuan, if the circumstances are relatively serious, shall be sentenced to fixed-term imprisonment of not more than two years or criminal detention; if the circumstances are relatively minor, he shall be given administrative sanctions at the discretion of his work unit or of the competent authorities at a higher level.

个人贪污数额不满五千元,情节较重的,处二年以下有期徒刑或者拘役;情节较轻的,由其所在单位或者上级主管机关酌情给予行政处分。

Units and individuals who employ aliens without permission shall terminate employment or the said aliens and may at the same time be fined from 5000 to 50000 Yuan, and be ordered to cover all the expenses of repatriating aliens whom they had employed.

对私自雇佣外国人的单位和个人,在终止其雇佣行为的同时,可以处5000元以上,50000以下的罚款,并责令其承担遣送私自雇佣的外国人的全部费用。

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推荐网络例句

I didn't watch TV last night, because it .

昨晚我没有看电视,因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来,在北京的很多小区里,电梯液晶电视被撤了下来。

I'm running my simile to an extreme.

我比喻得过头了。