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The liver fibrotic model was induced by CCl4 i.p for 5wk. Telmisartan was given at the same time model establishment in each intervened group by administration lasted for 6wk. Decollate to get the blood of all rats after 7 weeks . ALT、AST and ALB of serum was detected by automatic biochemistry equipment. Hyaluronic acid was detected by ELISA detection. Liver and spleen was obtained to calculate the index. The liver pathological changes were observed in each group of rats after HE staining to evaluate the therapeutic effect of Telmisartan; TGF-β1、PPAR-γand PDGF of liver tissue was detected by the method of immunohistochemistry respectively; The mRNA expression of TGF-β1、MMP-1、TIMP-1、α-SMA、PPAR-γand iNOS was detected by RT-PCR detection, respectively.

腹腔注射CCl4制备SD大鼠肝纤维化动物模型,连续灌胃6周,处死动物取血,检测血清ALT、AST、ALB;ELISA法测定血清透明质酸;取肝、睥,并计算肝、脾指数,组织切片HE染色后进行组织病理学疗效评估;用SP免疫组化法测定肝组织TGF-β1、PPAR-γ及PDGF蛋白表达;半定量RT-PCR方法检测肝组织TGF-β1、MMP-1、TIMP-1、α-SMA、PPAR-γ和iNOSmRNA的表达。

Methods Expressions of MMP2 and TGF-β1 gene from 43 human suprarenal epithelioma patients' carcinoma and tumor-adjacent tissues were detected by semi-quantitative reverse transcription polymerase chain reaction.

应用半定量逆转录-聚合酶链反应检测43例肾透明细胞癌患者癌与癌旁组织MMP2和TGF-β1的表达水平。

OBJECTIVE: Three sesquiterpene lactones 1-O-acetylbritannilactone, isoalantolactone and britannilactone were isolated from the roots of Inula helenium and the flowers of Inula japonica. The antitumor activities of the three sesquiterpenoids in the cell lines of HeLa, HEC-1, SHIN3, HOC-21 and HAC-2 were measured, and the relationship between structure and activity and the possible mechanisms were explored.

目的: 观察菊科植物中分离出的3种倍半萜化合物异土木香内酯、1-氧-乙酰大花旋覆花内酯和大花旋覆花内酯对体外培养的人子宫颈癌HeLa细胞、人子宫内膜癌HEC-1细胞、人卵巢透明细胞癌SHIN3及HOC-21细胞和人卵巢囊腺癌HAC-2细胞增殖的影响,研究这3种倍半萜化合物的体外抑制肿瘤细胞增殖作用及其结构与活性之间的构效关系,进而探讨3种倍半萜化合物的体外抑制肿瘤细胞增殖的可能机制。

The rubber products made of hydrated silica feature transparency and semitransparency, so it is a special raw material for making light-and multi-colored rubber products such ad high-grade hiking shoes, sports shoes, rubber tapes, tires etc.

用白炭黑制成的橡胶制品有明显的透明、半透明性,尤其适用于浅色、彩色橡胶制品、高级轻便旅游鞋、运动鞋、胶带、轮胎、玻璃胶、粘胶、可再分散型乳胶粉、纤维素醚等行业。

Fruit dehiscent siliques or silicles, linear, oblong, obovate, obcordate, elliptic, lanceolate, or suborbicular, often apically notched, strongly angustiseptate, sessile; valves keeled, winged or wingless; replum rounded; septum complete, membranous, translucent, veinless; style obsolete or prominent, exserted or included in apical notch of fruit; stigma capitate, entire or slightly 2-lobed.

果开裂的长角果或短角果,裂爿龙骨状,具翅的或无翅;假隔膜绕行;隔膜完成,膜质,半透明,无脉;花柱突出,外露的或在果的顶端的凹缺内包括的废退的或;柱头头状,全缘的或稍2裂。

The new type semi-aromatic transparent nylon has been successfully developed for the first time using cheaper monomers,including linear chain aliphatic diamines,terephthalic acid,isophthalic acid and so on,by means of polybasic copolycondensation.

采用无侧基的脂肪族混合二元胺、对苯二甲酸、间苯二甲酸等为单体,通过多元无规共缩聚方法制备了半芳香透明尼龙,研究了SA型透明尼龙的静态热机械性能和动态力学性能。

The results are unsure for experimental use;The rabbit's corneas that were removed with upper-half of corneal limbal epithelium lamella and erased the center corneal epitheliums were transparent with intact corneal epithelium;In the approach,the corneal and limbal epitheliums were burned with a cotton swab socked in 1 mol/L NaOH,there were 4 rabbits' corneal stroma happened perforation or ulcer and symblepharon,and the other one presented corneal epithelium phenotype.This is an applicable method to create the pathological model of corneal limbal stem cell total deficiency.

结果表明,处理后4周,全周角膜缘上皮板层手术切除,中央角膜上皮层用1 mol/L NaOH擦除的5只试验家兔角膜表面全部血管化、结膜化,未发生睑球粘连,角膜基质胶原纤维完整未见溃疡、穿孔等病变,细胞印迹学检查为结膜表型,可作为实验性角膜缘干细胞移植的病理模型;全周角膜缘上皮板层手术切除,中央角膜上皮用生理盐水擦除的5只试验家兔,有2只为结膜表型,另3只为角膜表型,观察期内结果不稳定;半周角膜缘上皮板层手术切除,中央角膜上皮层用生理盐水擦除的5只试验家兔,角膜表面透明,全部为角膜表型;直接用1 mol/L NaOH擦除角膜缘和中央角膜上皮的试验家兔,有4只角膜基质胶原纤维断裂、溶解,并伴有严重的溃疡、穿孔、睑球粘连等病变,不能用于移植试验,另1只角膜表面透明,未见结膜和新生血管长入,细胞印迹学检查为角膜表型。

Diagnosis/testing. A diagnosis of ocular albinism is probable in the presence of congenital nystagmus, iris translucency, and significant hypopigmentation of the ocular fundus periphery in males with normal skin pigmentation and foveal hypoplasia, reduced visual acuity, and aberrant optic pathway projection, as demonstrated by crossed asymmetry of the cortical responses on visual evoked potential. X-linked inheritance is documented by either a family history consistent with X-linked inheritance or the presence of typical carrier signs (irregular retinal pigmentation and partial iris transillumination) in an obligate carrier female.

诊断/检测。对于皮肤色素沉着正常、中央凹发育不全、视敏度降低以及视径投射异常(VEP,表现为视觉诱发电位中皮层反应的交叉不对称)的男性患者,当存在先天眼球震颤、虹膜半透明以及显著的眼基底层边缘色素减退的症状时,可被疑似诊断为眼白化病。X连锁性遗传则以存在与X连锁遗传一致的家族病史,或在一个应当为携带者的女性中存在典型的携带者迹象(视网膜色素沉着不规则以及部分虹膜透射)而被确认。

I normally use quite a lot of light sources; I place them so I can highlight details of the scene. In this image I have used 13 lights: 4 omni lights as ambient lighting, 2 to highlight the form of the engine, 3 spotlights to highlight the back of the engine, 3 highlight to stress the specular and the greasy effect on the shell, a spotlight behind the snail neck for the sub surface scattering, in addition to the sun with area shade and the sky with a HDRI with an atmosphere similar to the photograph of the road for the global lighting I have used a surface with an asphalt texture for the floor and the yellow lines only to be reflected on the engine and to add some radiosity to the snail body and shine.

通常我使用很多的光源,我到处放置它们,这样我才能照到足够多的细节,在这幅图里我使用了13盏灯,4 盏点光源作为环境光,2盏来照亮引擎的形状,三盏聚光灯用来照亮引擎的背面,三盏来强调蜗牛壳的高光及油腻的感觉,有一盏蜗牛脖子背后的灯光来表现3S半透明效果,另外还有一盏太阳光来获得各个区域的阴影,以及一个赋予了HDRI贴图的sky,来作为全局光,我使用了一种沥青材质作为地面材质,并让引擎能反射地面上的黄色带子,并为蜗牛身体与光射线增加了一些radiosity,以取得得与背景类似的灯光环境。

Lighting灯光I normally use quite a lot of light sources; I place them so I can highlight details of the scene. In this image I have used 13 lights: 4 omni lights as ambient lighting, 2 to highlight the form of the engine, 3 spotlights to highlight the back of the engine, 3 highlight to stress the specular and the greasy effect on the shell, a spotlight behind the snail neck for the sub surface scattering, in addition to the sun with area shade and the sky with a HDRI with an atmosphere similar to the photograph of the road for the global lighting I have used a surface with an asphalt texture for the floor and the yellow lines only to be reflected on the engine and to add some radiosity to the snail body and shine.

通常我使用很多的光源,我到处放置它们,这样我才能照到足够多的细节,在这幅图里我使用了13盏灯,4 盏点光源作为环境光,2盏来照亮引擎的形状,三盏聚光灯用来照亮引擎的背面,三盏来强调蜗牛壳的高光及油腻的感觉,有一盏蜗牛脖子背后的灯光来表现3S半透明效果,另外还有一盏太阳光来获得各个区域的阴影,以及一个赋予了HDRI贴图的sky,来作为全局光,我使用了一种沥青材质作为地面材质,并让引擎能反射地面上的黄色带子,并为蜗牛身体与光射线增加了一些radiosity,以取得得与背景类似的灯光环境。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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