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半乳糖酶

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Study on Gene Cloning, Expression and Expression Profiling in Tissues of Polypeptide: N-acetylgalactosaminyl Transferase 2

多肽:N-乙酰氨基半乳糖转移酶2(pp-GalNAc-T2,E.C.2.4.1.4)的基因克隆、表达及组织表达谱研究

Experimental Center of National Level One, Hubei Traditional Chinese Medica l College, Wuhan 430061)Abstract To investigate the protective effects of Jiaweisinisa n on acute liver injury induced by intraperitoneal injection of D-ga lac-tosamise, serum superoxide dismutase, malondialdehyde , glutathioe contents were measured. The pathological changes of liver wer e observed simultaneously. The results showed that JWSNS could decrease serum MD A content, but increase serum SOD and GSH activities in acute liver injury induc ed by D-GalN. It was also found that JWSNS could alleviate the degeneration and necrosis of the hypatocytes.

为研讨加味四逆散防治肝损伤的作用机理,通过动物试验,先用加味四逆散预防给药,再采用D-氨基半乳糖造成大鼠急性肝损伤模型,然后检测大鼠血清超氧化物岐化酶、丙二醛、还原型谷胱甘肽水平,同步观察该方对急性肝损伤大鼠体内脂质过氧化反应及肝脏病理改变的影响,结果表明该方可明显升高大鼠血清SOD、GSH水平,降低MDA水平,肝脏病理学检查亦表明该方使肝细胞变性坏死程度减轻。

Objective:To study the relations between β-1,4-GalT-I and the aging of Schwann cells.

目的:探讨β-1,4-半乳糖基转移酶I与雪旺细胞衰老的相关性。

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