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半乳糖

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Name Galactaric acid, Mucic Acid

中文名 半乳糖二酸,黏酸

Name Galactaric acid,Mucic Acid

用途中文名半乳糖二酸,黏酸

We have investigated on the chemical constituents of Nepeta partite collected from Gansu Zhuanglang, and twenty eight compounds were isolated from the methanol extraction of this species by chromatography techniques. Twenty five compounds were identified by means of chemical and spectra methods IR, FABMS, EI-MS,〓, DEPT, and 2D NMR), among which four compounds were new as isopimar-15-en-3β, 8β, 20-triol; phenylethanal-3-O-(2'-glycerin)-5-O-β-D-glucopyranoside; 3-O-linolenoylglyceryl-6'-O-(α-D-galactopyranosyl)-β-D-galactopyranoside; ethyl rosemarinate.

我们对采自甘肃庄浪的康藏荆芥进行了化学成分的研究,利用层析手段从该植物的甲醇浸膏中分离出二十八个化合物,经化学方法和波谱技术(红外,质谱,一维和二维核磁共振谱)鉴定了二十五个化合物的结构,其中四个为新的化合物,它们分别是:异海松-15-烯-3β,8β,20-三醇;苯乙醇-3-O-(2'-甘油基)-5-O-β-D-吡喃葡萄糖甙;3-O-亚麻酰基甘油-6'-0--β-D-吡喃半乳糖甙;迷迭香酸乙酯。

Results B, C can cause the hypomnesia of the Wistar rats(P<0.05) and result in decreasing amounts of pyramidale in CA1 sector of hippocampus. The neurotropic and glial nodule were observed.

结果 氯胺酮和D-半乳糖分别可致大鼠记忆功能明显下降(P<0.05)和海马CA1区锥体细胞减少,并可见嗜神经细胞现象和胶质细胞小结。

Based on relative literatures,this part has included five resesearch aspects as below.1 Fifteen compounds were isolated and purified by extraction,column chromatography,and their structures were determined on the basis of spectral analysis: acteoside(Ⅰ-1),isoacteoside(Ⅰ-2),crenatoside(Ⅰ-3),cistanoside F(Ⅰ-4),sinapoyl-4-O-β-D-glucoside(Ⅰ-5),adenosine(Ⅰ-6),β-siterol(Ⅰ-7),oleanic acid(Ⅰ-8), succinic acid(Ⅰ-9),caffeic acid(Ⅰ-10),protocatechuic aldehyde(Ⅰ-11),p-hydro xybenzyl alcohol(Ⅰ-12),β-daucosterol(Ⅰ-13),D-galacitol(Ⅰ-14),D-mannitol(Ⅰ-15).Ⅰ-4~15 were obtained from this plant for the first time,andⅠ-6,7,9,and 13 were isolated from Orobanche genus for the first time.2 The scavenging test of DPPH showed that most compounds have comparative antioxidant activity as L-ascorbic acid and part of them show better activity such as the O.coerulescens extract and phenylethanoid glycosides.Acteoside showed potent free radical scavenging effects with a median inhibition concentration of 25.6μg/ml.3 The anti-HBV activities of acteoside,isoacteoside and crenatoside were measured,and all of them showed suppressive activity on the expression of HBsAg and HBeAg in the HepG2.2.15 cell line.

本论文在文献调研基础上对紫花列当化学成分及生物活性进行了研究,并从免疫抗病毒角度探讨紫花列当中特征性成分类叶升麻苷的肝保护作用及其机制。1采用大孔树脂、硅胶和Sephadex LH-20等色谱技术对紫花列当进行系统的植物化学研究,从中分离得到19个化合物,利用UV和NMR等波谱手段及理化性质鉴定了其中的15个化合物,分别为类叶升麻苷(Ⅰ-1)、异类叶升麻苷(Ⅰ-2)、crenatoside(Ⅰ-3)、cistanoside F(Ⅰ-4)、sinapoyl-4-O-β-D-glucoside(Ⅰ-5)、腺苷(Ⅰ-6)、β-谷甾醇(Ⅰ-7)、齐墩果酸(Ⅰ-8)、琥珀酸(Ⅰ-9)、咖啡酸(Ⅰ-10)、原儿茶醛(Ⅰ-11)、对羟甲基苯甲酸(Ⅰ-12)、β-胡萝卜苷(Ⅰ-13)、D-半乳糖醇(Ⅰ-14)和甘露醇(Ⅰ-15除化合物Ⅰ-1、Ⅰ-2和Ⅰ-3外,其余化合物均为首次从该植物中分离得到。2)通过大孔树脂富集该药材有效部位苯乙醇总苷,并采用HPLC测得其所含特征性成分类叶升麻苷的含量可达80%以上。3DPPH自由基清除试验显示紫花列当提取物及其所含的苯乙醇苷类化合物均具有较好的抗氧化能力,其清除DPPH自由基能力接近于抗坏血酸。4采用卡介苗整体致敏、脂多糖离体攻击构建大鼠原代肝细胞免疫性损伤模型,在体外观察类叶升麻苷的保肝作用。

The formation of the by-products occurring with the aldononitrileacetates of glucose and galactose can be overcome by increasing the ratio of hydroxy-lamine hydrochloride to water in the solution before oximation and acetylation.

通过不断摸索,本文首次找到了在糖腈乙酰酯法制备单糖衍生物过程中控制葡萄糖和半乳糖不出杂峰的条件,并给出了一套快速、准确和实用的日常分析方法。

Iba 2002. Both the Arabidopsis fad5 mutant, which lacks an active chloroplast x-9 fatty acid desaturase and accumulates high levels of palmitic acid (16:0), and the fad6 mutant, which lacks an active x-6 fatty acid desaturase and accumulates high levels of palmitoleic acid (16:1) and oleic acid (18:1), have reduced levels of polyunsaturated fatty acids in the chloroplast galactolipids.

两个拟南芥突变体的叶绿体半乳糖脂含有较少的多不饱和脂肪酸:一种是拟南芥fad5突变体,它缺乏有活性的叶绿体的X-9脂肪酸去饱和酶,因而积累了高浓度的棕榈酸( 16:0 );另一种是拟南芥fad6突变体,它缺乏一个有活性的 X - 6脂肪酸脱氢酶因而积累了高浓度的软脂酸( 16:1 )和油酸( 18:1 )。

Pectinase is heterogeneous group of related enzymes that hydrolyze the pectic substances, which can break down complex pectin into simpler molecules like galacturonic acids.

果胶酶是一类分解果胶质的酶的总称,它能将复杂的果胶分解为半乳糖醛酸等小分子。

The optimum broken temperature of the tomato had been confirmed by determining the impact of broken temperature on the activity of pectous enzyme and the solvency of the product.

针对加工番茄品种,通过研究破碎温度对其果胶酯酶和聚半乳糖醛酸酶活力的影响,以及破碎温度对产品的冲调性的影响,确定番茄合适的破碎温度。

In the in vivo study, 100 ICR mice were randomly assigned to 5 groups after paired by body weight as following: Group N (negative control group, peritoneally injected by saline daily); Group C (positive control group, peritoneally injected by D-galactose and saline daily); Group L, M, and H (peritoneally injected by D-galactose and intragastric administered with TP at 100, 200, 400 mg/day, respectively). Mice were sacrificed for histology and biochemistry studies after 8 weeks.

在动物体内实验中,选择清洁级ICR纯系小鼠100只,按体质量随机分为5组:阴性对照组每天腹腔注射生理盐水,其余4组每天腹腔注射120 mg/kg D-半乳糖以建立小鼠衰老模型,同时阳性对照组每日以生理盐水灌胃,L、M、H组分别以每日100、200、400 mg/kg TP灌胃。8周后处死小鼠,获取心肌标本进行组织学研究和生化检测。

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