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Huangpu Town, Zhongshan City Niu Li maschinenbau 13823156967 Luosheng are handling the production of hydraulic machinery specialized factories, is an advanced manufacturing technology by relying on foreign countries and the rise of emerging enterprises, with a wealth of experience and solid strength, in order to provide security clients and high-efficiency, multi-angle logistics handling equipment; Huangpu Town, Zhongshan City Niu Li maschinenbau main products are: hand pallet trucks, manual hydraulic elevated cars, increased vehicle electro-hydraulic, self - increased hydraulic vehicles, hydraulic lift platform, hydraulic lift car tail plate, tank trucks, platform trucks carrying more than ten kinds of hydraulic equipment, we can according to customer demand for the development of new products; Zhongshan huangpu Cow town Machinery factory is the only set auto hydraulic lift tail plate development and the development, production and sales of integrated production enterprises, the product has passed the production of AQSIQ license certification, 70% of export to Hong Kong Products , Macao, Taiwan and other regions,"cow power" brand auto hydraulic lift tail plate has become a well-known domestic and foreign large enterprises and government agencies preferred brand; cow power Zhongshan maschinenbau domestic product are hand pallet trucks professional one factory, with an annual output has reached 50,000 units, the production of "cow power" brand hand pallet trucks have been the German TUV Certification Body of GS / CE certificate.

中山市黄圃镇牛力机械制造厂罗生13823156967是生产液压搬运机械的专业厂,是一个依托国外先进制造技术而掘起的新兴企业,拥有丰富的经验和雄厚的实力,为客户提供安全、高效率的、多角度的物流搬运设备;中山市黄圃镇牛力机械制造厂主要的产品有:手动液压搬运车、手动液压升高车、电动液压升高车、自行式液压升高车、液压升降平台、汽车液压升降尾板、油桶车、平台车等十余种液压搬运设备,我们可根据客户的需求开发各种新产品;中山市黄圃镇牛力机械制造厂是国内唯一集汽车液压升降尾板的开发与研制,批量生产以及销售的一体化生产企业,产品已通过国家质检总局的生产许可认证,产品70%出口港、澳、台等地区,"牛力"牌汽车液压升降尾板已经成为国内外众多知名企业及政府机关的首选品牌;中山市牛力机械制造厂是国内生产手动液压搬运车的专业工厂之一,年产量已达到50000台,生产的"牛力"牌手动液压搬运车已获得德国TUV认证机构的GS/CE证书。

The results show that these semi-high speed steels can be hardened remarkably by secondary hardening to meet the hardness requirements of cold rolling. The secondary hardness of the tested steels is increased with the contents of alloying elements such as Mo, V, Si and changed with quenching temperature to show two peaks.

研究结果表明,新型半高速钢有显著的二次硬化效应,能满足冷轧工作辊的硬度要求;随Mo、V和Si等合金元素含量升高钢的二次硬度升高,随淬火温度升高钢的二次硬度出现两次峰值。

Blood were obtained for blood RT and plasma endotoxin concentration check. 6 All data underwent ANOVA analysis. Results: After 3hrs of LPS injection, 1 in hypermetabolic sepsis group, the average HR went to 334/min, the average body temperature went to 41.0℃, while in control group they were 274.9/min and 38.2℃ respectively. p=0.000, presented significant statistical differences. The average BP and breath rate in HS group were 97.1mmHg and 94.3/min , while they were 95.9mmHg and 76.4/min in control group, respectively presenting no statistical differences. 2 In HS group plasma endotoxin concentration was 0.088EU/ml while it was 0.013 EU/ml in control group presenting statistical significance, p=0.002. 3 Blood white cell ratio and total white cell counting were 82.73% and 1.90×109 in HS group, while they were 64.39% and 7.58×109 in control group presenting very significant statistical differences(p=0.001). There was no statistical significances in RBC counting and hemocrit between two groups.

结果:LPS持续灌注3h后,结果如下:1)高代谢脓毒症组的心率升高至334.0次/min、体温升高至41.0℃,而对照组则分别为274.9次/min和38.2℃,两组间有显著的统计学差异,p=0.000;血压在高代谢脓毒症组是97.1mmHg,而对照组为95.9mmHg,两组间无统计学差异;脓毒症组的呼吸加快至94.3次/min,对照组则提高至76.4次/min,两组间无统计学差异(p=0.212);2)其血浆内毒素含量为0.088EU/ml,而对照组为0.013 EU/ml,两组间有显著的统计学差异,p=0.002;3)血中性粒白细胞比值升高至82.73%,对照组则为64.39%,两组间有显著的统计学差异(P=0.001);白细胞总数则明显下降至1.90×109/ml,而对照组则为7.58×109/ml,p=0.001,两组间有显著的统计学差异;两组间的红细胞数及血细胞比容均无统计学差异。

The profile of liver CYP450 induction by DEX in male rat After 4 daily i.p. administering of 0,25, 50 and lOOmg/kg/d DEX in male Wistar rat, it was determined the total CYP450 content, the mRNA and protein expression levels of CYP3A1, CYP3A2 and CYP2B1/2, and the ERD (CYP3A catalytic activity), PROD (CYP2B catalytic activity) and BROD (total CYP450 catalytic activity) in livers.

DEX对雄性大鼠肝脏CYP450的诱导效应雄性Wistar大鼠腹注0、25、50和100mg DEX/kg/d诱导处理4天后,测定大鼠肝脏总CYP450含量,CYP3A1、CYP3A2和CYP2B1/2的mRNA及蛋白表达水平,肝脏红酶素脱甲基酶(ERD,CYP3A活性),苄氧基试卤灵脱乙基酶(PROD,CYP2B活性),苯氧基试卤灵脱乙基酶(BROD,总CYP450活性),结果表明,CYP450含量、ERD、PROD和BROD在DEX多次诱导后都有升高,CYP3A1 mRNA表达水平、蛋白含量和酶活性有明显的升高,剂量效应关系明显;CYP3A2蛋白也有明显升高,而其mRNA表达水平却没有变化,提示CYP3A1和CYP3A2的诱导机制可能不同。

The profile of liver CYP450 induction by DEX in male ratAfter 4 daily i.p. administering of 0,25, 50 and lOOmg/kg/d DEX in male Wistar rat, it was determined the total CYP450 content, the mRNA and protein expression levels of CYP3A1, CYP3A2 and CYP2B1/2, and the ERD (CYP3A catalytic activity), PROD (CYP2B catalytic activity) and BROD (total CYP450 catalytic activity) in livers.

DEX对雄性大鼠肝脏CYP450的诱导效应雄性Wistar大鼠腹注0、25、50和100mg DEX/kg/d诱导处理4天后,测定大鼠肝脏总CYP450含量,CYP3A1、CYP3A2和CYP2B1/2的mRNA及蛋白表达水平,肝脏红酶素脱甲基酶(ERD,CYP3A活性),苄氧基试卤灵脱乙基酶(PROD,CYP2B活性),苯氧基试卤灵脱乙基酶(BROD,总CYP450活性),结果表明,CYP450含量、ERD、PROD和BROD在DEX多次诱导后都有升高,CYP3A1 mRNA表达水平、蛋白含量和酶活性有明显的升高,剂量效应关系明显;CYP3A2蛋白也有明显升高,而其mRNA表达水平却没有变化,提示CYP3A1和CYP3A2的诱导机制可能不同。

The blood pressure of.1 of pathology physiology mechanism that SAS causes CVD breathes time-out to be able to bring about airframe in elevatory Morpheus anoxic, sympathetic is excessive and excited, element of serous catechu phenolic amine, kidney and hemal endodermis element are elevatory, bring about hemal easy of hemal convulsion; to shrink the function is disorder, can make blood-vessel flowing flesh happening reframes and fleshy, systemic blood-vessel obstruction adds element of the kidney when; is chronic and anoxic, system of hemal and nervous element is activationed, bring about blood pressure to lift. Obstruction of way of energy of life of patient of OSAS of disease of blood of 1.2 low oxygen increases, cause air current to interrupt, breath pauses, at the same time airframe gets used to low oxygen environment gradually, breathing centre drops to low oxygen and sensitivity of disease of blood of tall carbonic acid, breath suspends a frequency increasing, farther aggravating airframe is anoxic. 1.3 heads are self-adjusting the function drops normal person changes quickly in systematic circulation blood pressure when, the head can be passed adjust independently functional generation protects effect, make change of cerebral blood flow not big.

SAS诱发CVD的病理生理机制。1血压升高睡眠中呼吸暂停可导致机体缺氧,交感神经过度兴奋,血浆儿茶酚胺、肾素以及血管内皮素升高,导致血管痉挛;血管舒缩功能紊乱,可使血管平滑肌发生重构和肥厚,全身血管阻力增加;慢性缺氧时肾素—血管紧张素系统被激活,导致血压升高。1.2低氧血症OSAS患者气道阻力增加,造成气流中断、呼吸暂停,同时机体逐渐适应低氧环境,呼吸中枢对低氧和高碳酸血症敏感性下降,呼吸暂停次数增加,进一步加重机体缺氧。1.3脑自动调节功能下降正常人在体循环血压快速变化时,脑可通过自主调节功能产生保护效应,使脑血流量变化不大。

Expressions of ChAT mRNA and protein were enhanced in 9 of the 18 lung tumor specimens; and expressions of ChoK mRNA and protein were increased in 14 of 18 lung tumor specimens compared with those of normal lung tissues. 8 of 18 lung cancer specimens were obvious increased in expressions of both ChoK and ChAT.

结果 18例肺癌的PET/CT图像均显示胆碱放射性摄取明显增高,18例肺癌组织细胞中,14例Chok mRNA及蛋白质的表达比正常肺组织升高,9例肺癌组织细胞ChAT mRNA及蛋白质表达升高,其中8例Chok及ChAT表达均升高

Experimental results indicate that the film growth rate increases with the increase of current density and the decrease of the temperature.

实验结果表明氧化膜的生长速率随电流密度的升高升高,随温度的升高而下降。

The gasification efficiency increased and the molar fraction of H2 decreased with an increase in the reaction temperature. The decomposition of PVA was more complete at higher temperatures. At 24 MPa, 500℃ and 120 s, the TOC remove rate, the carbon gasification rate and the hydrogen gasification rate were up to 71.46%, 67.97% and 157.24% respectively. A change in the residence time had no significant effect on the molar fraction of gas production but an increase in the residence time could enhance the gasification efficiency of PVA. It was found that the intermediates were mainly alkane, cycloparaffin, aromatic hydrocarbons, and low-molecular weight acids. It was supposed that PVA was degraded into small molecules through breaking of C-C bonds. Parts of the molecules were converted into H2, CO, CH4 and CO2 while some was converted into aromatic hydrocarbons.

过程探索发现:反应温度的升高能提高PVA气化效率,但气体产物中H2的含量随反应温度的升高有所下降;随着反应温度的升高,PVA分解趋于彻底,在压力24MPa、温度500℃、停留时间120s的条件下,TOC去除率、有机碳气化率和氢气化率分别达到71.46%,67.97%和157.24%;停留时间的变化对气体产物含量没有明显的影响,但延长停留时间能提高PVA的气化效率;PVA气化反应中间产物主要为链状烷烃、环烷烃、芳香烃及小分子酸,根据中间产物出现的顺序推测PVA的降解为由C-C键断裂形成小分子物质,这些小分子物质一部分转化为H2,CO,CH4和CO2,一部分形成难降解的芳香族化合物。

YMDD mutation: HBV YMDD mutation were developed in 12 lamivudine recipients, whereas the treated group had no incidence of HBV YMDD variation, there were significant difference between two groups (p=0.000). YMDD mutation resulted in increase of the mean HBVDNA levels (p=0.000), but no contribution to serum ALT diversification (p>0.05). 2. Precore nt1896 mutation: Precore nt1896 mutation incidence had no difference between lamivudine recipients and objects who received combination therapy of Kidney-invigorating Granule and Marine Injection, and patients of HBeAg negative and HBeAg positive had a close incidence of precore mutation as well as. Precore nt1896 mutation had no influence on serum ALT level. The occurrence of precore nt1896 mutation contributed to serum HBVDNA load increased and worse response of HBVDNA extenuation. 3. HBV genotype: The baseline of serum HBVDNA gradually increase in turn of genotype B, genotype C and genotype B/C. Genotype B seemed to obtain higher rate of serum HBVDNA loss and HBeAg/anti-HBe seroconversion after combination therapy of Kidney-invigorating Granule and Marine Injection, differencing with lamivudine therapy.

疗效相关因素研究:1YMDD变异:对照组有12例检出YMDD变异,治疗组无1例检出,两组比较有显著性差异(P=0.000);发生YMDD变异者血清HBVDNA和ALT水平均有所升高,HBVDNA平均水平高于非变异者(P=0.000);血清ALT与非变异者无明显差异(P>0.05)。2前C区nt1896变异:前C区nt1896变异发生率在治疗组和对照组以及HBeAg阴性和HBeAg阳性患者之间均无明显差异(P>0.05);1896c变异对血清ALT水平无明显影响;治疗组发生1896c变异者,其HBVDNA平均水平较之未变异者明显升高(P<0.05),治疗后HBVDNA下降幅度明显低于未发生1896c变异者(P=0.000)。3HBV基因型:血清HBVDNA基础水平在B、C、B/C混合型间存在明显差异(P<0.05),按B型、C型、B/C混合型依次升高;治疗组HBVDNA阴转率、HBeAg/抗-HBe血清转换率,B型似乎高于C型和B/C混合型,但无统计学意义(P>0.05);对照组HBVDNA阴转、HBeAg/抗-HBe改变在B、C、B/C混合型间无明显差异(P>0.05)。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

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