化学疗法的

This is the website of Antimicrobial Agents and Chemotherapy.

这是《抗菌剂和化学疗法》杂志的网站。

Several other poster presentations reinforced the message that once-weekly epoetin was effective, although none of these others had a comparator dose. Two posters presented results from meta-analyses of epoetin alfa clinical trials. One was carried out by Pere Gascon, MD, PhD, and colleagues, from the University of Barcelona, in Spain, and involved 4296 patients with mixed tumor types, while the other, reported by Mario Dicato, MD, from the Luxembourg Medical Center, involved 2019 patients with breast cancer. Both concluded that 40,000-IU epoetin alfa is effective and well tolerated; it ameliorates the impact of chemotherapy on hemoglobin and improves quality of life, thus representing "good anemia management," the researchers concluded.

许多其他的壁报研究同样证实每周投予一次红血球生成素是有效的，虽然其他研究中未使用比较组；另两项比较红血球生成素阿法临床试验结果的综合分析，一项是由Pere Gascon医师与其来自西班牙巴塞隆纳大学的同事，收纳了4，296位各种肿瘤种类病患的研究；另一篇是来自Luxembourg医学中心Mario Dicato医师，收纳2，019位乳癌病患的研究，这两项研究的结论都是40，000单位的红血球生成素阿法同样有效、且耐受性佳；该疗法降低化学疗法对血红素的不良影响，且改善了生活品质，因此可以说为是「良好贫血处理」的标竿。

Our data show that the circadian clock and haem biosynthesis are reciprocally regulated and suggest that porphyrin-containing molecules are potential targets for therapy of circadian disorders.

这说明，卟啉衍生物（B12含有卟啉）是如癌症等生物节律失调疾病的潜在治疗药物，而且通过细胞周期调节物质与生物钟之间的联系，还可用在接受化学疗法和放射疗法的患者身上。

Due to the impression of recto colon ca with recurrance liver metastasis,he is admitted for chemotherapy.

因直肠大肠癌和复发肝脏转移的压力，他接了化学疗法。

The recombinant proteins were purified according to the protocol of Ni-NTA Agarose and detected by SDS-PAGE, and TLC. Western blotting was used to identify their immunoreactivities with the serum of patient with clonorchiasis.

寄生性蠕虫以胞质GSTs为主，参与对由虫体代谢和宿主免疫系统所产生的脂质过氧化物和细胞毒性的羰基的解毒，对虫体的生存起重要的作用，是免疫疗法、化学疗法和免疫诊断潜在的靶标。

"For patients with good performance status and reasonable pain control, induction chemotherapy, with or without consolidative chemoradiation, is a strategy worthy of further investigation for patients with locally advanced disease," Robert Wolff, MD, associate professor of medicine at the University of Texas MD Anderson Cancer Center in Houston, told attendees at the meeting.

休士顿德州大学安德森癌症中心Robert Wolff医师向与会者表示，对病况较佳且疼痛获得合理控制的病患而言，诱导化学疗法，不管是否加上固化化学放射线治疗，对於进展性疾病是值得研究的治疗方式。

Management. Treatment of manifestations: Early diagnosis and treatment of RB and RB-related tumors can reduce morbidity and increase longevity; care is best provided by specialists from ophthalmology, pediatric ophthalmology, radiation oncology, oncology; treatment options depend on tumor stage, number of tumor foci (unifocal, unilateral multifocal, or bilateral), localization and size of the tumor within the eye, presence of vitreous seeding, and age of the child; treatment options may include enucleation, cryotherapy, photocoagulation, photochemistry, external beam radiation therapy, and radiation therapy using episcleral plaques; newer options include systemic chemotherapy combined with or followed by local therapy.

处理。 表征的治疗： RB 和 RB 相关肿瘤的早期诊断和治疗能减轻病状、延长存活时间；护理最好由眼科学、小儿眼科学、肿瘤学和放射肿瘤学等方面的专业医师来提供；治疗方案的选择取决于肿瘤阶段、病灶数量（单病灶、单侧多病灶或双侧病灶）、眼内肿瘤的位置和大小、玻璃体散布的存在与否以及患儿的年龄；治疗选项可能包括摘出术、冷冻疗法、光凝固术、光化学法、外照射放疗和用巩膜外斑块进行的放射治疗；新的治疗选项包括与局部治疗结合的或先行的系统化学疗法。

Burstein, MD, PhD, from the Dana-Farber Cancer Institute and Harvard Cancer Center in Boston, Massachusetts, reported phase 2 results of a trial that randomized 62 women with stage IV breast cancer to metronomic chemotherapy (oral cyclophosphamide 50 mg/d once daily and oral methotrexate 2.5 mg twice daily on days 1 and 2 each week) with or without intravenous bevacizumab (10 mg/kg every 14 days).

Burstein医师报告一项第2期临床试验结果，这项临床试验收纳了62位第4期乳癌接受节律性化学治疗（在每周的第一、二天口服cyclophosphamide每天50毫克，以及口服methotrexate 2.5毫克每天两次），加上或是不加上bevacizumab（10毫克公斤，共14天）；「节律性」疗程被定义为使用低剂量、重复投予的化学疗法。

Several other poster presentations reinforced the message that once-weekly epoetin was effective, although none of these others had a comparator dose. Two posters presented results from meta-analyses of epoetin alfa clinical trials. One was carried out by Pere Gascon, MD, PhD, and colleagues, from the University of Barcelona, in Spain, and involved 4296 patients with mixed tumor types, while the other, reported by Mario Dicato, MD, from the Luxembourg Medical Center, involved 2019 patients with breast cancer. Both concluded that 40,000-IU epoetin alfa is effective and well tolerated; it ameliorates the impact of chemotherapy on hemoglobin and improves quality of life, thus representing "good anemia management," the researchers concluded.

许多其它的墙报研究同样证实每周投予一次红血球生成素是有效的，虽然其它研究中未使用比较组；另两项比较红血球生成素阿法临床试验结果的综合分析，一项是由Pere Gascon医师与其来自西班牙巴塞隆纳大学的同事，收纳了4，296位各种肿瘤种类病患的研究；另一篇是来自Luxembourg医学中心Mario Dicato医师，收纳2，019位乳癌病患的研究，这两项研究的结论都是40，000单位的红血球生成素阿法同样有效、且耐受性佳；该疗法降低化学疗法对血红素的不良影响，且改善了生活质量，因此可以说为是「良好贫血处理」的标竿。

The rationals of anti-angiogenesis are the following: the therapeutic target is tumor endothelial cells which are more genetically stable, more homogeneous, and with lower mutation rate; the anti-angiogenesis drugs can contact endothelial cells directly, with higher potency and lower drug barriers and side effects; the aim of anti-angiogenesis therapy is to block the oxygen and nutrition supply from vessels, instead of killing tumor r ells per se; the aim of anti-angiogenesis is to reduce tumor size instead of eradicate tumor which are different from traditional chemotherapy.

使用抗血管新生疗法根据的理论基础为以肿瘤血管的内皮细胞为治疗药物的攻击标的；肿瘤血管的内皮细胞基因比较稳定、同质性高、而且突变率低；投与的药物可以直接接触内皮细胞，减少投与药物屏障，因此增加有效投与药物的能力及减少药物副作用；以截断供应肿瘤氧气养分的血管为目标：以减小肿瘤的体积大小为目的，与传统化学疗法以根除肿瘤的目标不同。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。