化学生物学

With its unique molecular structure and outstanding bio-activities, qinghaosu has been proven as a worthy subject for in-depth studies with profound influence, not only for pharmacy, but also for phytochemistry, biogenetic synthesis and organic synthetic chemistry, chemical biology, etc. A great amount of work has been done in the last 30 years, with a lot more issues to be explored. Researchers need to seize the opportunity and make more achievements.

青蒿素以其独特的分子结构和杰出的生物活性显示出它是一有深远影响的研究对象，不仅对于药学，而且对于植物化学、生源合成、有机合成化学、化学生物学等学科都是一个可以大有作为的课题。30年来国内外已做了不少工作，但是还有更多的问题有待探索，机不可失，时不再来，期待着在綻放青蒿素的故土上结出更多的果实。

objective to isolate and purify the antimicrobial peptides with anti-toxoplasma gondii activity isolated from the haemlymph of musca domestica larvae.methods the antimicrobial peptides of musca domestica larvae were induced by infection and injury were isolated and purified by trituration,centrifugalization and column chromatography.then the antimicrobial peptides with anti-toxoplasma activity were sieved by mtt colorimetric method and haemacytometry.results it was found that two antimicrobial peptides had anti-toxoplasma activity through resource s cationic column chromatography and superdex g75 gel column chromatography.conclusion the two antimicrobial peptides with anti-toxoplasma activity existing in the haemlymph of musca domestica larvae had different anti-toxoplasma effect.

作者单位：山西医科大学寄生虫教研室，太原 030001；化学生物学与分子工程教育部重点实验室山西大学生物技术研究所目的从家蝇幼虫血淋巴中分离纯化具有抗弓形虫作用的抗菌肽。方法通过损伤加感染的方法诱导家蝇幼虫大量表达抗菌肽，然后经过研磨、离心和层析等过程，将家蝇幼虫抗菌肽进行分离纯化，采用四甲基偶氮噻唑蓝比色法和血细胞计数法筛选对弓形虫速殖子有抑制作用的抗菌肽。结果经resource s阳离子柱和superdex g75凝胶柱层析后，筛选出2种对弓形虫速殖子有杀伤作用的抗菌肽。结论家蝇幼虫血淋巴中存在抗弓形虫作用的抗菌肽，而且不止一种，但其效果有所不同。

The main points were as follows:Influence of exogenous Fe3+, Fe2+ on LOX catalysis was studied as viewed from chemicobiology for the first time.

具体研究内容、实验主要结果及结论为：首次从化学生物学视角研究外源Fe2+、Fe3+等对LOX结构及其催化进程的影响。

Department of Chemical Biology,School of Pharmaceutical Sciences, Perking University,Beijing(100083);Department of Chemistry,Xinjiang University,Ulumqi830046

北京大学药学院化学生物学系。北京(100083)；新疆大学化学系，乌鲁木齐 830046

Covering the chemistry of liquid-phase oxidation of organic compounds, this book includes the results of analysis with the parabolic model as applied to reactions of peroxyl radicals with C-H bond of different organic compounds.

在有机化学和生物学方面的氧化和抗氧化剂有機化学と生物学の面でのアンチオキダントと酸化します包括有机化合物的液相氧化的化学，这本书象适用于peroxyl 激进主义者与不同的有机化合物的C-H 契约的反应的那样用抛物线的模型包括分析的结果。

It has also been discovered that the inhibition of GAPDH attenuates the diabetic disease symptom in model animals.

这一研究在最新一期自然。化学生物学杂志上有所报道。

By now, the development of caging groups for photon switch has become an interesting research area.

迄今，发展和用于光敏开关的光敏剂已成为化学生物学研究的重要方向。

Chemical biology is rapidly establishing itself as an important interdisciplinary field through cross\|link and fusion.

化学生物学正在成为一个重要的新兴交叉学科，它是化学与生物学和医学等学科领域相互交叉、相互渗透的产物。

This includes: clinical radiotherapy, combined modality treatment, experimental work in radiobiology, chemobiology, hyperthermia and tumour biology, as well as physical aspects relevant to oncology, particularly in the field of imaging, dosimetry and radiation therapy planning.

它刊登于放射肿瘤学感兴趣领域，这些领域包括：临床放射治疗学，肿瘤多学科治疗方案，放射生物学的实验性研究，化学生物学，热疗学和肿瘤生物学，以及与肿瘤有关的物理学领域，尤其是影像学，剂量学和放射治疗计划。

It covers areas of interests relating to radiation oncology, including clinical radiotherapy, combined modality treatment, experimental work in radiobiology, chemobiology, hyperthermia and tumour biology, as well as physical aspects relevant to oncology, particularly in the field of imaging, dosimetry and radiation therapy planning.

该杂志发表研究论文和评论，涵盖了和放射肿瘤学相关的领域，包括临床放疗法，综合治疗，放射生物学实验工作，化学生物学，高热与肿瘤生物学以及和肿瘤学相关的物理方面，尤其是影像、放射剂量测定以及放射疗法计划等领域。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。