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化学合成

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With its unique molecular structure and outstanding bio-activities, qinghaosu has been proven as a worthy subject for in-depth studies with profound influence, not only for pharmacy, but also for phytochemistry, biogenetic synthesis and organic synthetic chemistry, chemical biology, etc. A great amount of work has been done in the last 30 years, with a lot more issues to be explored. Researchers need to seize the opportunity and make more achievements.

青蒿素以其独特的分子结构和杰出的生物活性显示出它是一有深远影响的研究对象,不仅对于药学,而且对于植物化学、生源合成、有机合成化学、化学生物学等学科都是一个可以大有作为的课题。30年来国内外已做了不少工作,但是还有更多的问题有待探索,机不可失,时不再来,期待着在綻放青蒿素的故土上结出更多的果实。

Chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; pheromone biosynthesis-activating neuropeptide; PBAN; pheromone-binding protein; scent gland; scents; scent marking behavior; territorial behavior

化学感官;化学感受;化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学线索;化学感知;信息素生物合成激活肽;PBAN;信息素-结合蛋白;臭腺;气味;臭迹的行为;区域性行为

Chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; pheromones; pheromone receptors; pheromone biosynthesis-activating neuropeptide; PBAN; pheromone-binding protein

化学感官;化学感受;化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学线索;化学感知;信息素;信息素受体;信息素生物合成激活肽;PBAN;信息素结合蛋白

Chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; pheromones; pheromone receptors; pheromone biosynthesis-activating neuropeptide; PBAN; pheromone-binding protein; pheromone glands

化学感官;化学感受;化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学线索;化学感知;信息素;信息素受体;信息素生物合成激活肽;PBAN;信息素结合蛋白;信息素腺

Review articles only; chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; vomeronasal organ; vomeronasal epithelium; vomeromodulin; pheromone-binding protein; pheromone biosynthesis-activating neuropeptide; PBAN; Dufour's gland; scent gland; scents; scent marking behavior; territorial behavior; trail following behavior; feeding behavior; mating behavior; reproductive behavior

唯一综述;化学知觉;化学感受;化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学因子;化学感觉;梨鼻器;犁鼻骨上皮;vomeromodulin;信息素-结合蛋白;信息素生物合成-激活神经肽;PBAN;杜氏腺;臭腺;气味;臭迹状态;区域性行为;踪迹跟随行为;摄食行为;交配行为;生殖行为

Chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; pheromone-binding protein; pheromone biosynthesis-activating neuropeptide; PBAN; Dufour's gland; oviposition deterring; queen pheromone

化学感官;化学感受;化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学线索;化学感知;信息素结合蛋白;信息素生物合成激活肽;PBAN;杜氏腺;产卵阻止;母蜂信息素

Chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; vomeronasal organ; vomeronasal epithelium; vomeromodulin; pheromone-binding protein; pheromone biosynthesis-activating neuropeptide; PBAN; Dufour's gland; scent gland; scents; scent marking behavior; territorial behavior; feeding behavior; mating behavior; reproductive behavior; trail following behavior

化学知觉;化学感受化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学因子;化学感觉;梨鼻器;犁鼻骨上皮;vomeromodulin;信息素-结合蛋白;信息素生物合成-激活神经肽;PBAN;杜氏腺;臭腺;气味;臭迹行为;区域性行为;摄食行为;交配行为;生殖行为;踪迹跟随行为

Chemical senses; chemoreception; chemoreceptors; infochemicals; semiochemicals; chemical stimuli; chemical communication; chemical cues; chemical perception; pheromones; pheromone receptors; pheromone traps; pheromone emission; pheromone biosynthesis-activating neuropeptide; PBAN; pheromone-binding protein; pheromone glands; Dufour's gland; scent gland; scents; scent marking behavior; territorial behavior; trail following behavior; trail pheromone; aggregation pheromone; alarm pheromone; marking pheromone; oviposition deterring; queen pheromone; sex pheromone

化学感官;化学感受;化学接受体;信息化学;化学信息素;化学刺激物;化学通讯;化学线索;化学感知;信息素;信息素受体;信息素诱骗;信息素发射;信息素生物合成激活肽;PBAN;信息素结合蛋白;信息素腺;杜氏腺;臭腺;气味;臭迹行为;区域性行为;踪迹跟随行为;追踪信息素;群集信息素;报警信息素;标记信息素;产卵阻止;母蜂信息素;性信息素

Combinatorial chemistry is a type of synthetic strategy which systematically connects a set of"building blocks"such as amino acids, nucleotide and small organic molecules to yield a large array of diverse molecular entities described as a combinatorial library. It also refers to the process of screening the compounds with the expective activity from the library.

组合化学是将诸如氨基酸、核苷酸、有机小分子等构建单元按某种组合方式连接起来,合成出包含大量化合物的化学库,并从中筛选出具有某种物理、化学或药理活性化合物的一套合成策略和筛选方案。

In the thesis, a series of novel single and multi-armed oxadiazole bridging ligands and pyridyl-4, 5-imidazole dicarboxylic acid ligands have been synthesized. The coordination chemistry of these novel ligands with transition metal ions was investigated. In addition, two 1, 3, 4-oxadiazole bridging ligands end-capped by chelating Schiff-base coordination sites have been designed and synthesized. The coordination chemistry based on one of the two ligands with metal ions was primarily investigated.

本文报道了一系列新颖的含1, 3, 4-Oxadiazole杂环的单臂及多臂有机配体,研究了它们与过渡金属离子的配位反应化学;合成了吡啶基-4,5-咪唑二羧酸有机配体,研究了它们在水热条件下与过渡金属离子的配位反应化学;另外,还合成了1, 3, 4-Oxadiazloe杂环桥联的双Schiff-base有机配体,初步探讨了其与过渡金属离子的配位反应化学。

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