化学制剂

We Investigated the species of diseases and insect pests, species of natural enemies, distribution and dominant species in export vegetable bases in Shandong Province. Dynamics of main diseases and insect pests were studied.2. We investigated the main control technologies for diseases and insect pests, types and application methods of pesticides.3. Effects of crop varieties, fertilities and cultivation on diseases and insect pests, production and pesticide residues were examined.4. Control effects and application technologies of frequency trembler grid lamps, greenhouse ozone machine and insect-proof net were tested.5. By research, seven biological preparations and twelve chemical pesticides with high activity, low toxicity and low residue were screened.

主要结果如下：1查清了山东省出口蔬菜基地蔬菜病虫害发生种类，天敌种类、分布、并评价上风种；探明了主要病虫发生消长规律。2查清了山东省出口蔬菜基地目前病虫害防治的主要应用技术、施药种类及主要施药方式。3明确了作物品种、肥力、栽培方式等农业措施对病虫发生、产量和农残的影响。4明确了频振式杀虫灯、温室病害臭氧防治机、防虫网等物理措施防治效果及其应用技术。5通过实验，筛选出7种生物制剂和12种安全有效低毒低残留化学农药品种。

Natural alcohol series products are suitable for making vanishing cream etc..

本品作为主要的制剂和助剂用于洗涤剂等日用化学领域。

DESCRIPTION】the ingredients of the product comes from abyssopelagic fishes of special pure and clean sea areas, adopting Limited Enzymic Degraded Technology, a self-owned intellectual property, that is using compound bioenzyme preparations at a low temperature to extract active ingredients through a special low-temperature extraction process and specific sheared protein to ensure the bioactivity of Collagen.

本品原料来自纯净、无污染的特定海域中的深海鱼类，采用具有自主知识产权的限制性酶切制备多肽技术（Limited Enzymic Degraded Technology），在低温下使用复合生物酶制剂，通过特殊低温萃取工艺提取有效成分，通过特异性的剪切蛋白质，保证了胶原蛋白原有的生物活性，并将原分子量为30万左右的胶原蛋白分子降解成3500左右的胶原蛋白多肽（约含30个左右的氨基酸残基），其分子长度降至30—50nm，集中度达到99.5%以上，呈白色或淡黄色，无异味，无杂物，不添加任何激素和化学物质，没有任何毒副作用。

Compounds 2-4 were isolated from the plants of Chloranthaceae for the first time.The antibacterial activities of these six compounds were tested for the first time.Some compounds may have potential for future study and development as plant-derived oral antibacterial agents.

化合物1为1个新的天然产物，化合物2~4为首次从金粟兰科植物中分离得到，首次测定了6种香豆精类化学成分的抗菌活性，一些化合物具有进一步研究开发成为抑制口腔细菌的天然药用植物制剂的潜力。

CYP and P-gp mediated PP-CD interactions and the research methods have been discussed in this review.

本文综述了药物代谢酶CYP及药物转运蛋白P-gp介导的植物制剂—化学药物的相互作用及常用的研究方法。

Atorvastatin calcium, the substance known by the chemical name (R--2 -(4-fluorophenyl)-b, ddihydorxy-5 -(1-methylethyl)-3-phenyl-4 -(phenylamino carbonyl-1H -pyrrole-1 -heptanoic acid hemi calcium salt is known as HMG-CoA reductase inhibitor and is used as an antihypercholesterolemic agent.

阿托伐他汀钙，已知化学名为(R--2-(4-氟苯基)-b，d-二羟基-5-(1-甲基乙基)-3-苯基-4-(苯基氨基羰基-1H-吡咯-1-庚酸半钙盐的物质，已知其为HMG-CoA还原酶抑制剂，并用作抗高胆固醇药。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

II. The State practices the special-purpose control system with respect to the production, management, use and export of ephedrine (including extracts from ephedra grass and chemically synthesized, laevorotatory and dextrotatory) as well as their saline categories such as ephedrine hydrochloride, ephedrine oxalic, ephedrine sulphate and raw products of ephedrine (including ephedrine extracts, ephedrine extract powder and ephedra powder), ephedrine derivatives and prescribed preparations made with ephedrine as the raw material.

二、国家对麻黄素(含从麻黄草提取和化学合成的，包括左、右旋)及其盐类如盐酸麻黄素、草酸麻黄素、硫酸麻黄素和麻黄素粗品(含麻黄浸膏、麻黄浸膏粉、麻黄草粉)、麻黄素衍生物以及以麻黄素为原料生产的单方制剂等的生产、经营、使用、出口实行专项管理制度。

The State practices the special-purpose control system with respect to the production, management, use and export of ephedrine (including extracts from ephedra grass and chemically synthesized, laevorotatory and dextrotatory) as well as their saline categories such as ephedrine hydrochloride, ephedrine oxalic, ephedrine sulphate and raw products of ephedrine (including ephedrine extracts, ephedrine extract powder and ephedra powder), ephedrine derivatives and prescribed preparations made with ephedrine as the raw material.

二、国家对麻黄素(含从麻黄草提取和化学合成的，包括左、右旋)及其盐类如盐酸麻黄素、草酸麻黄素、硫酸麻黄素和麻黄素粗品(含麻黄浸膏、麻黄浸膏粉、麻黄草粉)、麻黄素衍生物以及以麻黄素为原料生产的单方制剂等的生产、经营、使用、出口实行专项管理制度。

The State practices the special-purpose control system with respect to the production, management, use and export of ep hedrine (including extracts from ep hedra grass and chemically synthesized, laevorotatory and dextrotatory) as well as their saline categories such as ep hedrine hydrochloride, ep hedrine oxalic, ep hedrine sulphate and raw products of ep hedrine (including ep hedrine extracts, ep hedrine extract powder and ep hedra powder), ep hedrine derivatives and prescribed pr ep arations made with ep

国家对麻黄素(含从麻黄草提取和化学合成的，包括左、右旋)及其盐类如盐酸麻黄素、草酸麻黄素、硫酸麻黄素和麻黄素粗品(含麻黄浸膏、麻黄浸膏粉、麻黄草粉)、麻黄素衍生物以及以麻黄素为原料生产的单方制剂等的生产、经营、使用、出口实行专项管理制度。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。