化合物

Chiral ligand-exchange chromatography is one of the basic chromatography method for enantiomer separation, in which chiral ligands and metal ions are two essential elements to determine the chiral selectivity.

手性配体交换色谱法是分离手性化合物的基本方法之一，其中手性配体和金属离子是决定手性化合物分离选择性的根本因素。

The crystal structures of them show the photochromism is due to the photoisomerization only from enol form to keto form. According to the results of structure analyses, the intermolecular proton transfer mechanism is proposed for photochromism. We also observed their acidichromism in solution.

采用单晶XRD法得到了这五种化合物的结构，根据结构解析，推测四种光致变色化合物的变色机理可能是分子间质子转移，即吡唑啉酮由烯醇式结构变为酮式结构。

As stated previously, we have assumed that all MCs are equipotent and we are treating them as a group of compounds and not as single compounds.

如前所述，我们认为，所有主持人都equipotent ，我们对待他们作为一个群体的化合物，而不是单一的化合物。

Based on the previous literatures, the following major innovation works were carried out in this dissertation:(1) The derivatization reaction conditions of ephedrine and pseudoephedrine with sensitive derivation reagent in aqueous system were studied and two new methods were developed for the assay of them by microemulsion electrokinetic chromatography and micellar electrokinetic chromatography with LIF detection. The sensitivity and analysis times were greatly improved compared with the previous reports;(2) A new method of CZE with indirect LIF detection was developed for the simultaneous determination of six coumarin compounds (esculin, esculetin, isofraxidin, genistein, naringin and sophoricoside) with fluorescein as the probe. The proposed method enlarges the application range of LIF detector, and provides new approach for the analysis of certain compounds difficult to derivatize;(3) Based on the above research, an MEKC with indirect LIF detection method for the simultaneous determination of adenine and guanine in DNA extracts from fungus, maize and soybean was established;(4) A new method for the investigation of the complexes formed between human serum albumin and ampicillin sodium under the simulated physiology conditions using laser light scattering technique was developed.

该论文在综述前人工作的基础上，开展了如下未见文献报道的创新性的研究工作：(1)使用灵敏的衍生试剂对麻黄碱和伪麻黄碱在水体系中的衍生反应条件进行了系统研究，建立了微乳电动色谱-激光诱导荧光检测法和胶束电动色谱—激光诱导荧光检测法测定麻黄碱和伪麻黄碱的灵敏分析新方法，与以前的报道相比，灵敏度和分析时间均有很大改善；(2)使用荧光素钠作为背景荧光试剂，建立了同时分析测定六种黄酮类化合物(秦皮甲素、秦皮乙素、异秦皮定、染料木素、柚皮苷和槐角苷)的毛细管区带电泳—间接激光诱导荧光检测新方法，扩大了激光诱导荧光检测的应用范围，对难衍生化合物的分离分析提供了一种新思路和新途径；(3)以荧光素钠作为背景荧光试剂，建立了一种用于同时测定食品提取DNA中的腺嘌呤和鸟嘌呤含量的胶束电动色谱—间接激光诱导荧光检测新方法；(4)用动态和静态激光散射法研究了模拟生理条件下人血清白蛋白与氨比西林钠盐相互作用所形成的复合物，为药物分子与蛋白质的相互作用、药代动力学等的研究提供了一种新思路。

Selected the best cultivate condition by cultivated on four different media under different conditions; Observated morphology perperties; Studied on biology perperties by germ tube testing, Carbohydrate fermentation testing, Tween testing and Esculin dissociation; lysis testing.

选择四种不同的培养基分别在不同温度条件下培养，选出最优培养条件；通过光学显微镜、电子显微镜观察菌落及菌体的形态学特点；通过芽管试验、碳水化合物发酵试验、碳水化合物同化试验、沙堡培养基生长试验、过氧化氢酶试验、七叶苷分解试验、吐温试验研究该菌的生理、生化学特征；应用PCR技术通过特异性的引物扩增得到菌属特异性的片段，最后测定扩增片段的核苷酸序列，从而进行菌种的分析、鉴定。

A better understanding of the role of PPAR in insulin action system will be critical in developing more efficacious and safe agent s that act on PPAR and benefit patients with type 2 diabetes. The main content is followed: Synthesis and analysis of 1,3-dicarbonyl compounds. Make use of easily available cheap reagent such as 2-naphthol, 6-hydroxyquinoline, 1,2-dibromoethane, 4- hydroxybenzaldehyde, dimethyl malonate, 2-{4- [(2-napthoxy)ethoxyl] benzyl} malonates and 2-{4 [(1,2,3,4-tetrahydro-6 -quinolinoxy)ethoxyl] benzyl } malonates were synthesized through 6-8 steps in virtue of Williamson, Knoevenagel reaction, Pd/C catalyzed hydrogenation with mild conditions and high yield. The total yield of 40-50%.

本论文的主要内容和研究结果如下： 1，3-二羰基类化合物的合成及分析，采用2-萘酚、6-羟基喹啉、1 ，2二溴乙烷、对羟基苯甲醛、丙二酸二甲酯等常见易得试剂，利用Williamson反应、Knoevenagel反应、钯碳加氢等条件温和且收率高的方法，分别合成了2-{4- [(2-萘氧)乙氧基]苄基}丙二酸衍生物和2-{4 [(1，2，3，4-四氢-6-喹啉氧基)乙氧基]苄基}丙二酸衍生物两个系列8个化合物，经6-8步反应，总收率为40-50%，具有一定绿色化学特性。

In this paper, we provided biomimetic synthetic methods for tetrahydroisoquinoline by using the benzimidazoline as a new tetrahydrofolate coenzyme model with 2-(3, 4-dimethoxyphenyl)ethylamine as nucleophile reagents under the condition of acid.

在心血管用药中，某些四氢异喹啉类化合物及其衍生物对心律失常、心肌缺血、高血压和心力衰竭有显著的治疗作用，对四氢异喹啉类化合物及其衍生物进行结构改造，进而发展成为药品成为当今医药的研发重点。

Three series of liquid crystals were synthesized in this study. In the first part of this study, a rectangular liquid crystal, compound 8, with two ethynyl groups and two oxymethylene groups used to link to phenyl groups and biphenyl groups with the central phenyl core respectively exhibits smetic phases.

本研究成功合成出三系列化合物：第一系列为合成以二炔基二亚甲氧基为中心之盘状液晶，并在二亚甲氧基尾端引入可进行光聚合反应之二丙烯酸酯基，得到层列型液晶化合物8，其液晶相温度范围在46.1~74.8℃，且单体8对光与热之稳定性较差，高温下容易自行聚合。

In this study, main chain of 4,4'-Biphenol combine different side chains to discuss polymer ~ polymer which synthesizes by the difference of structure of 1-Bromobutane、1-Bromoocatane、1-Bromododecane.To examinate luminance property and judge the correction for the structure of polymer ~ polymer by FT-IR、NMR-1H、UV、PL, in the meanwhile,to investigate into radiation wavelength under the condition of different side chains.

中文摘要 1。本实验是利用4，4'-Biphenol为起始物，与Allyl bromide反应，产生丙烯基芳基醚化合物，再利用克莱森重排反应将丙烯基转至邻位，然后在将OH基转变为不同链长的烷基醚合成出聚合物耤I），以FT-IR、NMR-1H、UV、PL测定其发光性质及判断产物结构是否正确，并探讨化合物在不同侧链之条件下，比较其放射波长。

We found compound 35 exhibited charge transfer fluorescence, but 36 showed the major emission from local excited state.

我们发现化合物(35)有电荷转移的放光产生，而化合物(36)主要的放光则来自於区域性的激态。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。