化

The inhibitor for DNA methyltransferase, 5-azacytidine (5-azaC), can demethylate the methylated DNA and restore transcription of genes. High dose homocystine can mediat DNA methylation and suppress gene expression.

应用甲基转移酶抑制剂5-氮杂胞苷(5-azacytidine， 5-azaC)可以使甲基化的启动子去甲基化，启动基因重新转录；高浓度同型半胱氨酸(homocystine， Hcy)可以介导基因甲基化而抑制其表达。

The constitution mode and inclusion information of assembly drawings has been analyzed according to the expression contents and demand of rolling mill assembly drawings. The dendriform assembly model has been setup to express the assembly drawings contents. Under AutoCAD graphic environment, assembly drawings are realized with parts consolidation technology. Generating of local view, dimensioning, technical requirement, expression of list and title panel has been realized too. Generating of parts has been discussed and processing strategy of parametric drawings has been pointed out.

根据轧机装配图的表达的内容和要求，分析装配图的构成方式和应包含的信息，提出了建立树状装配模型来表达装配图的内容，基于AutoCAD图形环境，采用了用零件图拼装实现装配图生成的解决方案，并实现了装配图中有关局部视图的生成、尺寸标注、技术要求、标题栏和明细表的表达，并讨论了零件图的生成问题，提出了参数化绘图数据的处理策略，即利用PDB可编程对话框工具，设计了零部件的参数化编程框架，完成了工作辊、支承辊、机架等零部件的参数化编程。

In recent years, the electronic equipment goes toward to little size and constantly improves on high efficiency. However, to microminiaturize and densify the electronic device / chip will lead to the result of increasing heat capacity transition.

近年来，电子设备不断在缩小化及高效能上精进，然而在元件缩小化且密集化的同时，亦增加了热传量。

The effect of N-phosphoamino acids on plant cells'membrane permeability was investigated by osmotic method. It was found that in all N-phosphoamino acids, only some phosphoryl polar amino acids such as DIPPSer, DIPPThr, DIPPHis, DIPPAsp, DIPPGlu, DIPPAsn and free serine, threonine could increase the water permeability in plant cell membrane. For example, after 20min. treatment by 1. 5mM DIPPSer, the deplasmolysis time of onion cells was shortened 50%.

三、通过透性实验研究了N-磷酰化氨基酸对洋葱、豌豆等植物细胞膜水透性及溶质透性的影响，发现在所有的N-磷酰化氨基酸及自由氨基酸中，仅有部分N-磷酰极性氨基酸和自由的丝、苏氨酸对植物细胞膜上水透性有增强作用，如1.5mM N-磷酰化丝氨酸可使洋葱细胞质壁复原时间缩短一半以上。

A sample-pretreated method of ether-extraction-precolumn-derivation was established, and the chromatographic conditions, which was used for determinating the derivant of extracted UDCA, were decided to be Hypersil C_(18) column(250×4.6mm, 10μm), acetonitrile-methol-0.005mol·L~(-1) phosphoric buffer-triethylamine(50:27:42:0.25, adjusted to pH3.0±0.1 by phosphoric acid) as mobile phase with detective UV wavelength at 247nm and column temperature at 35℃.

建立了乙醚提取-柱前衍生化血浆样品预处理方法，采用Hypersil C_(18)柱(250×4.6mm，10μm)，乙腈-甲醇-0.005mol·L~(-1)NaH_2PO_4缓冲液-三乙胺(50：27：42：0.25，磷酸调节pH3.0±0.1)为流动相的HPLC法，以溴苯乙酮为衍生化试剂，在247nm处测定家兔血浆中熊去氧胆酸衍生化产物。

Establishing experimental animal model of immunized fibrosis could contribute to research on extracellular matri and cytokine. they turns out that the ingredient of Desmodium pulchellum can relieve extra growth and deposit of ECM and adjust the level of relative cytokine, such as TGF-β1 and IFN-γ, benefit to effect of hepatic anti-fibrosis.

结果证明排钱草生物碱类成分能减轻肝纤维化的基本病理改变即减少肝细胞外基质的过度增生和沉积，调节与肝纤维化密切相关的TGF-β1、IFN-γ等细胞因子水平，向着有利于减轻肝纤维化的方向发展。

Based on reviewing of functionalization of saturated carbon by catalytic oxidation with metalloporphyrins and metal phthalocyanines as a mimic of the enzyme cytochrome P-450, two reaction systems of which one was the preparation of 4, 4'-dinitrostilbene-2, 2'-disulfonic acid from 4-nitrotoluene2-sulfonic acid and the other was the preparation of 4, 4'-bis (dimethylamino -diphenyl) phenylmethanol from 4, 4'-bis (dimethylamino-diphenyl) phenyl methane , were specifically studied as carfunctionalization and oxyfunctionalization of saturated carbon.

本文在全面综述金属卟啉和金属酞菁类模拟细胞色素P-450酶催化剂催化氧化饱和碳原子功能化的基础上，选择由4-硝基甲苯-2-磺酸制取4，4'-二硝基二苯乙烯-2，2'-二磺酸和由4，4'-二苯基甲烷制取4，4'-二苯基甲醇两个反应体系进行饱和碳原子碳功能化和氧功能化的具体研究。

For the models by MMFI is a nonlinear differential equation with variable coefficients and the 'nonlinearity' brings discommodiousness to analyse the nature and quantification of a control system, it applies brim linearization method to better MMFI. By transforming 'triangle wave' membership functions of the base elements into 'rectangle wave' membership functions, we get three models which represent different aspect respectively. By simulating second order system and analysing the errors of the results, a conclusion is drawn, that is, the model obtained by brim linearization method has a good precision in contrast with the real model.

由于模糊推理建模法得到的模型是变系数非线性微分方程，这种&非线性&对该控制系统的某些定性或定量分析带来不便，因此应用边缘线性化方法对模糊推理建模法进行改进，将基元的隶属函数由&三角波&改成&矩形波&，从而得到了三个模型，这三个模型各有侧重，通过对二阶系统进行仿真，分析仿真结果，从而给出了关于边缘线性化方法的结论，即由边缘线性化方法得到的系统模型对该系统的真实模型有较高的逼近精度。

In order to realize double configuration of control and protection system of HV electric power system,based on the doubling of protection system,the double configuration of disconnector operating circuit is synchronistically made.

为实现高压系统控制与保护系统的双重化配置，电力系统在保护双重化的基础上，同步进行了断路器操作回路的双重化配置，在操作箱及断路器的更换过程中，遇到了诸如压力闭锁、防跳、非全相跳闸等相关回路的配置等问题，对实际工作值得分析以及进行相应的处理。

Said cathode material is compound material consisting of copper and selenonium, especially having different chemical element proportional of copper - selenium compound: copper diselenide, copper selenide, cuprous selenide.

该阴极材料是由铜和硒组成的化合物材料，具体为含有不同化学元素比例的铜-硒化合物：二硒化铜、硒化铜、硒化亚铜。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。