化

Our idea of easy dimensional driving includes mainiy:(1) a driving mechanism of construction constraints and dimensional constraints,(2) automatic graphic recognition of constraints,(3) a bothway cross dimensional linked list for storing dimension sparse matrices and for recalling them,(4) a reasonable method of constraint consistence checking,(5) the linking of movement of 2D views,(6) a method for creating a sequence graphic library.

随着二维与三维设计技术的交叉发展，目前的参数化设计主要有两个分支：①面向纯二维的图形参数化，其特点是二维图形为多拓扑环的复杂图形；②面向三维的基于CSG特征造型的参数化，用于拉伸扫描的单拓扑环的二维图形参数化及空间任意曲面的参数化是其特点。

Except heptanoyl chitin, four of them,i.e.acetyl chitin,propionyl chitin,butyryl chitin and hexanoyl chitin,had high degree of substitution(from 1.5 to 2.0)and exhibited lyotropic liquid crystalline behavior and cholesteric phase.

文摘：四种羧酰化甲壳素即乙酰化、丙酰化、丁酰化和己酰化甲壳素在二氯乙酸溶液中均呈现胆甾型溶致液晶相。

The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以克拉霉素为起始原料，经水解、乙酰化、环碳酸酯化、氧化、脱碳酸酯化、酰化、环氨基甲酸酯化和环合等反应合成目标化合物。

Many literatures focus on preterm prediction study and evaluate every predictor. The predictors include cervical length and the size of some of fetal organs measured by ultrasound; the level of fFN, IGFBP-1, IL investigated in cervicovaginal fluid, serum relaxin, CRP and HbA1c in mother's blood, MMP-8, MCP-1 and ITAC in amniotic fluid which correlated with infection.

早产的预测是研究热点，大量文献分别从超声测量学角度，包括宫颈长度，胎儿某内脏的测量；宫颈阴道分泌物中多项指标，如胎儿纤维结合蛋白、磷酸化及脱磷酸化胰岛素样生长因子连接蛋白-1、白细胞介素的测定；血生化分析，如血清松弛肽、C反应蛋白、糖化血红蛋白含量的变化及羊水化验与感染有关的一些因子，如快速基质金属蛋白酶8、单核细胞趋化蛋白-1、γ干扰素诱导T细胞α趋化因子等，阐述各指标对早产的预测价值。

Although the biological significance of DNA methylation has been recognized to some extent, the mechanisms of DNA methylation regulation and of the establishment of tissue-specific DNA methylation pattern in somatic cells are still unclear, since the knowledge of the enzymes responsible for de novo DNA methylation and demethylation of DNA is very limited and up to now only two functional DNA methyltransferases in mammals have been cloned.

目前，虽然对DNA甲基化的作用已有一定认识，但DNA甲基化的调节以及发育过程中组织特异的DNA甲基化谱的建立机制还不清楚。问题主要在于对催化重新甲基化和去甲基化反应的酶的了解很少。至今仅克隆出两种有功能的哺乳动物DNA甲基转移酶。

In chapter four, the preperation of ytterbium diiodide was examined. The reductive cleavage of Se-Se bond and S-S bond induced by ytterbium diiodide was investigated. The reaction of diselenides and disulfides with allylic bromide promoted by ytterbium diiodide was also examined. The intermolecular Barbier-type reaction induced by ytterbium diiodide was studied. In the last section of this chapter, the intermolecular reductive coupling of nitriles with azides induced by samarium diiodide was investigated.

第四章，研究了二碘化镱的制备方法，以及二碘化镱作为一种优良的单电子转移试剂在有机合成中的应用：二硒醚的Se--Se键和二硫醚S-S键的还原断裂，及其在合成烯丙基硒醚，硒代酯和烯丙基硫醚，硫代酯中的应用，实验结果表明二碘化镱也能促进分子间的Barbier反应，而文献认为二碘化镱不能促进分子间的Barbier反应；最后研究了二碘化钐促进的叠氮化合物与腈的交叉还原偶联反应，一步高收率地制备脒的方法。

Two important routes currently being used to improve molybdenum disilicide mechanical property and oxidation are the alloying approach and the doping approach.

介绍了二硅化钼合金化及掺杂改性的研究进展，对几种重要合金化元素和掺杂元素改性的二硅化钼材料进行了评述，并在此基础上提出了高性能二硅化钼材料研究开发的重点和方向。

The hypermethylation of 5 CpG in promoter region serves as a mechanism of the inactivation of RASSF1A gene. This mechanism has been widely confirmed in multiple tumorgenesis including prostate carcinoma cell line DU145. Object Our study is to disclose the epigenic mechanism of the carcinogenesis of prostate cancer. Including: 1. We use demethylation agents in combination with chemotherapeutic drugs, to disclose whether demethylation agents can enhance the anticancer effect of chemotherapeutic drugs. 2. to study whether demethylation drugs can affect the methylation level of RASSF1A gene in.

目的 本研究旨在探讨前列腺癌的表遗传学发生发展机制，包括： 1、甲基化抑制剂与多种化疗药物联合应用，探讨二者间的协同作用，增强化疗药物疗效； 2、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因甲基化水平的影响； 3、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因及蛋白表达的影响，以期为进一步深入探索通过改变抑癌基因的甲基化而为前列腺癌发生机制和基因治疗提供有意义的数据和理论依据。

The alternative method of O-demethylation,methane sulfonic acid/DL-methionine and hydrobromic acid were investigated.

方法在以蒂巴因为原料，经氧化、氢化、酰化、氰化、去氧甲基、水解、N-烯丙基化得到纳洛酮的合成路线中，分别采用甲磺酸/DL-甲硫氨酸和氢溴酸代替三溴化硼进行去氧甲基化和后续水解反应。

Our main products are oilfield chemicals—Calcium Bromide、 Zinc Bromide、Sodium Bromide; Pharmaceutical and Photographic Grade Potassium Bromide、 Ammonium Bromide、Hydrobromic Acid、 Lithium Bromide as well as organic bromine flame retardants including Tetrabromobisphenol A and so on.

主要生产油田化学品---溴化钙、溴化锌、溴化钠；医药及照相用溴化钾、溴化铵、氢溴酸、溴化锂及有机溴系阻燃剂四溴双酚A等。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。