动质

Twenty-seven differential proteins were tested by MALDI-TOF-MS, and 16 were identified. Of the 16 proteins, 13 were up-regulated in patients with HCC, including heat-shock protein 27, member RAS oncogene family (RAB14), actin, alpha 1 antitrypsin, RNA-binding protein regulatory subunit and so on. By contrast, the levels of proteins such as PDX6, HSPA8 and MnSOD were significantly reduced in HCC patients.

对27个差异蛋白质点进行了质谱分析，鉴定出16个蛋白质，在HBV相关性HCC患者PBMC中表达明显增强的有热休克蛋白质27、ras癌基因家族(RAB14)、肌动蛋白、α1-抗胰蛋白及RNA结合蛋白调节亚基等13个蛋白点；而PDX6、HSPA8及锰超氧化物歧化酶在HCC患者PBMC中低表达。

RESULTS: A well-resolved and reproducible 2-DE pattern of PBMC was obtained from patients with HBV associated HCC or LC. For HCC, the mean number of protein spots was 1186±43, with an average matching rate of 91.6%, and for LC, the mean number of protein spots was 1013±41, with an average matching rate of 90.2%. Twenty-seven differential proteins were tested by MALDI-TOFMS, and 16 were identified. Of the 16 proteins, 13 were up-regulated in patients with HCC, including heat-shock protein 27, member RAS oncogene family (RAB14), actin, alpha 1 antitrypsin, RNAbinding protein regulatory subunit and so on. By contrast, the levels of proteins such as PDX6, HSPA8 and MnSOD were significantly reduced in HCC patients.

结果：得到了分辨率较高、重复性较好的HBV相关性HCC及LC患者PBMC双向凝胶电泳图谱，HBV相关性HCC及LC患者PBMC凝胶的平均蛋白质点数分别为1186±43及1013±41；组内的平均匹配率分别为91.6%，90.20%对27个差异蛋白质点进行了质谱分析，鉴定出16个蛋白质，在HBV相关性HCC患者PBMC中表达明显增强的有热休克蛋白质27、ras癌基因家族(RAB14)、肌动蛋白、α1-抗胰蛋白及RNA结合蛋白调节亚基等13个蛋白点；而PDX6、HSPA8及锰超氧化物歧化酶在HCC患者PBMC中低表达。

Methods Dietary-induced hyperlipidemia were induced in female SD rats by given 4% cholesterol and 1% cholic acid diet for 16 weeks.

用含4%胆固醇和1%胆酸钠的高脂饲料饲喂大鼠建立高脂模型，观察大鼠血脂、24h尿蛋白、血肌酥和肾小管间质病理改变，免疫组化法检测肾小管上皮细胞巢蛋白和α-平滑肌肌动蛋白表达。

However, at the beginning of PVR process, stimulated and activated by the initiative factors, RPE begin to dislocate from Bruchs membrane , migrate, proliferate, dedifferentiate, transdifferentiate and secrete provisinal extracellular matrix proteins, followed by membrane formation and contraction on both surfaces of the neuroretina and in the vitreous body, resulted in tractional retinal detachment.

PVR发生后，RPE受到始动因素的刺激，开始活化，脱离原位，去分化，移行、增生、发生表型转化等，并分泌细胞外基质(extracellular matrix， ECM)，最终在视网膜前后表面和玻璃体内形成具有收缩能力的增生膜，造成牵拉性视网膜脱离。

On the basis of the information obtained through field geological survey and indoor integrated petrological and petrochemical studies, it has been found that there is a clear and sharp pulsatory intrusive contact between various rock units of the rock body and a number of dark dioritic microinclusions are present. The rocks are characterized by a relatively low total REE content, relative enrichment in K, Rb, Ba and Th and relative depletion in Cr, Ti, Nb, Sr and P.

根据野外地质调查资料和室内的岩石学、岩石化学等特征的综合研究成果，发现该岩体各单元之间呈脉动式侵入接触，接触界线清晰，且含有较多暗色闪长质微粒包体；稀土总量较低，K、Rb、Ba、Th元素相对富集，Cr、Ti、Nb、 Sr、Zr、P元素相对亏损。

The solid-phase microextraction technique was evaluated for the determination of furoic acid and creatinine in urine. For furoic acid, the alkaline hydrolysis step was first performed to hydrolyze the furoic acid-glycine conjugate to free furoic acid.

本研究利用固相微萃取(solid-phase microextraction， SPME)动与气相层析质谱仪之结合，建立尿中呋喃甲酸与肌酸酊的分析技术，以提供评估呋喃甲醛暴露之生物侦测工具。

The range of mental disease is very wide, include implement qualitative sex disease, if old age is gawkish, much,move paralysis of disease, head to wait, and functional sex disease, like angst disease, depressed disease, schizophrenia, wait into addiction.

精神疾病的范围很广，包括器质性疾病，如老年痴呆、多动症、脑瘫等，以及功能性疾病，如焦虑症、抑郁症、精神分裂症、成瘾等。

The detection rates of methicillin-resistant S. aureus and penicillin-nonsusceptible S. pneumoniae were 15.9% and 84.3%, respectively. The prevalence of ESBLs-producing strains in Klebsiella pneumoniae, Escherichia coli, Serratia spp and Enterobacter cloacae were 31.2%, 46.2%, 94.8% and 16.8% respectively. The resistance rates of Hemophilus influenzae and Hemophilus parainfluenzae to ampicilin were 40% and 36% respectively.

耐甲氧西林金黄色葡萄球菌检出率为15.9%；对青霉素不敏感的肺炎链球菌（包括PISP和PRSP）检出率为84.3%；肺炎克雷伯菌、大肠埃希菌、粘质沙雷菌和阴沟肠杆菌产ESBLs的检出率分别为31.2%、46.2%、94.8%和16.8%；流感嗜血杆菌和副流感嗜血杆菌对氨苄西林的耐药率为36%和40%；铜绿假单胞菌和鲍曼复合不动杆菌对亚胺培南的耐药率分别为10.7%和13.2%。

Study Design. An animal study to achieve posterolateral intertransverse process spine fusion using mesenchymal stem cell.

研究设计，在动物体上行腰椎后路融合术，术中使用骨髓间充质干细胞。

Signalling through CXCR4 mediates actin polymerization and pseudopodia formation in cells, and induces chemotactic and migration to target organs. In addition, CXCR4-SDF-1 axis can promote tumor angiogenesis and growth.

CXCR4在肿瘤组织中的表达明显高于正常组织，而肿瘤常见转移部位均为CXCR4的配体基质细胞衍生因子-1(stromal cell derived factor-1，SDF-1)表达丰富的器官，SDF-1与CXCR4结合后可使细胞肌动蛋白丝聚合，形成伪足，从而定向诱导肿瘤细胞迁移到特定的靶器官；此外，CXCR4与其配体SDF-1相互作用可以促进局部新生血管作用，利于肿瘤生长。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。