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动脉缩窄

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METHODS: Ameroid constrictors were placed on the proximal left circumflex coronary artery in 14 pigs.

Ameroid 缩窄器被放置在最接近的左方的降声调符号上在14 头猪的花冠的动脉。

Objective To explore a new method of interventional therapy for coarctation of aorta complicated by patent ductus arteriosus.

目的 探讨主动脉缩窄合并动脉导管未闭介入治疗新方法。

METHODS:Hypertrophy model was established using renal artery coarctation.

应用肾动脉缩窄术复制Wistar大鼠心肌肥厚的动物模型。

Pale and edematous papilla was found in 46% of the involved eyes at admission.

眼底检查 46%的患眼视盘呈现苍白性水肿,67 5 %伴有动脉缩窄

The Sprague-Dawley rats (220-250g) were anesthetized with sodium Phenobarbital (60mg/kg, i. p.). The left renal artery was separated and clipped with a 0.3 mm silver clip.

在SD大鼠,通过用银夹缩窄左肾动脉,建立两肾一夹型大鼠高血压模型。

The pleural superficial blood vessels were smooth, while the constrictions of smooth muscle cells and round imprints of endothelial nuclei occurred on the surface of the subpleural and parenchymal arteriole and venule.

肺胸膜面浅层微血管的铸型表面光滑,胸膜下和肺实质内微动脉和微静脉的铸型表面可见平滑肌细胞形成的缩窄,以及圆形内皮细胞核的压痕。

METHODS 24 patients diagnosed coarctation of aorta or interrupted aortic arch with congenital heart defects, aged 6 to 197 days average (78±58)days,weighed 2.3 to 5.6 kg average (4.0±0.8)kg,were randomly divided into DHCA group(n=15) and SACP group(n=9).Continuous SACP was established via the innominate artery cannulation after reaching target temperature, the flow rate was kept 15-30 ml/.

动脉缩窄或主动脉弓中断合并心内畸形患儿24例,其中男20例,女4例,年龄6~197 (78±58)d,体重2.3~5.6(4.0±0.8)kg,随机分为DHCA组(15例)和SACP组(9例),后者在降至目标温度后经无名动脉顺行插管行持续性SACP,灌注流量15~30 ml/。

In present study, the model of the low shear stress in carotid or hypertension was established by the ligation of partial distal branches of the left common carotid or the coarctation of aorta in SD rats respectively. In some rats the low shear stress in carotid was accompanied by the hypertension. The media and intimal thickness, as well as the ratio of vessel thickness to inner diameter were determined by morphometrical approach.

本文通过腹主动脉缩窄、结扎左颈总动脉的部分分支建立了高血压、左颈总动脉低切应力、以及高血压伴有低切应力大鼠动物模型;几何形态学方法观测左颈总动脉的壁厚及壁厚/内径比的变化;金属蛋白酶谱法分析MMP-2活性;免疫印迹法检测信号通路分子p-Akt、p-38分子以及Rho GDIα的表达变化。

The pleural superficial blood vessels were smooth, while the round imprints of endothelial nuclei along the vascular axis and circular constrictions were found on the subpleural arteriole and the terminal arteriole.

胸膜面浅层的微血管铸型表面比较光滑,胸膜下微动脉和终末微动脉表面可以看到沿血管长轴排列的呈圆形的内皮细胞核的压痕,以及规律分布的环状缩窄。

METHODS: Left ventriclar pressure overload hypertrophy in rats was produced by abdominal aorta banding between bilateral renal aortas for 12 weeks.

采用缩窄大鼠肾动脉间腹主动脉的方法造成后负荷过载所致的左心室肥厚模型。

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